“highly significant”

A significant effect of the co-culture conditions revealed that culture of hBM-MSCs in tumour spheroids with MDA-MB-231s and T47Ds had a highly significant effect on the spheroid size of hBM-MSCs across 5 days (hBM-MSCs alone, +MDA-MB-231s or +T47Ds; F (2,6) = 357.792, p = 0.001).

This mixed model revealed a highly significant main effect for time, F (7 463.7) = 75.54, p < 0.001, f 2 = 0.38.

Considering the iAUC for serum leptin in the 0–4 h postprandial lap, this difference among the study groups became highly significant ( p < 0.001) ( Figure 2 B).

Rasburicase produced a highly significant (p < 0.001) decrease in UAL within 24 hrs after the first injection (group 1: 0.51 ± 0.39 mg/dL, group 2:1.83 ± 1.07 mg/dL) with a response rate of 100% and 93% respectively.

The reduction of exploratory visits in the VPA group was robust and highly significant (GLM, p < 0.001) throughout acclimation, nose-poke- and side preference learning phases (VPA group −55% vs. control; Figure 2B ).

A subgroup analysis of the number of ADR reports finally revealed that the increment in ADR-reporting was solely and highly significant (P < 0.001) related to ADRs of non CAM drugs.

5A , the suppressive effect of AIBP on HIV replication was significantly lower in cells from HLA-B*35 donors on day 3 postinfection and had completely disappeared by day 5 p.i., whereas AIBP-mediated suppression was still highly significant ( P < 0.001) in two other donors with non-B*35 genotype.

different = 2), as an additional level 1 predictor in a second step produced a highly significant effect for this variable, β = 34.21, t = 9.30, p < 0.001, and it rendered the effect for the CL variable non-significant, β = 0.59, t = 0.28, p = 0.78.

Baseline analysis showed that among categorical variables, the smoking rate was 46.667% in the POAG 1 group and 34.807% in the POAG 0 group with no significant difference (χ 2 = 1.838, P = 0.175), alcohol drinkers accounted for 6.667% in POAG 1 and 6.265% in POAG 0 with no significant difference (χ 2 = 0.008, P = 0.928), and males constituted 53.333% of POAG 1 and 44.556% of POAG 0 with no significant difference (χ 2 = 0.926, P = 0.336); however, the positivity rate of vb001_s1 was significantly lower in POAG 1 (30.000%) than in POAG 0 (84.556%) with a highly significant difference (χ 2 = 65.820, P < 0.001).

These differences were highly significant (Mann-Whitney rank sum test, P < 0.001 for both segments).

Falls were highly significant among boys in all age groups ( p < 0.001) with the exception of infants (≤ 1 year old).

The differences between groups of CPR and mortality at 30 days were all highly significant (p< .001) before adjusting for patient specific factors.

2 ), which was highly significant in patients without RSWA in all sleep periods ( p < 0.001 for total and NREM sleep periods, p = 0.001 for REM sleep periods).

The correlation between final adherence and MPR was highly significant (Spearman-Rho test; r = 0.62; p ≤ 0.001).

Multiple comparisons Tuckey tests showed that there was a substantial increase in surface microhardness of the CESP group ( p < 0.05) and a highly significant increase ( p < 0.001) recorded by the UDD group when compared to the -ve CTL group.

Statistical analysis shows highly significant statistical correlation between miR-34a and miR-125b expression levels with P value <0.001* ( Figure 1 ).

Across all four fields, a highly significant correlation was observed universally between the community composition of the Green cluster and the PCS severity (JD: R 2 = 0.87, P < 0.001; JF: R 2 = 0.78, P < 0.001; TX: R 2 = 0.81, P < 0.001; JF: R 2 = 0.79, P < 0.001) (Fig. 3C ).

Though the differences were small, they were statistically highly significant ( P < 0.001).

The increase in exhaled breath condensate hydrogen concentration was highly significant (0.86 ± 0.28 μM; 95% CI, 0.74-0.98; P < 0.001) after 4 weeks of treatment with dapson.

Although the age differences are highly significant ( P < 0.001), they have no clinical relevance.

7 The higher-order interaction Relevant Stimulus × Duration × Experiment was highly significant, F (1, 58) = 17.1, p < .001, η p 2 = .228, confirming the significant difference between Experiments 1 and 2 in RT data with regard to S-S binding.

The bivariate correlation analyses revealed a highly significant negative correlation between serum spermidine levels and age ( p < 0.001) (Fig. 3 ).

Gender played a vital role, with females exhibiting higher acceptance (n = 166) compared to males (n = 72), which was a highly significant difference (p < 0.001).

However, there are virtually equal frequencies of balanced and unbalanced products at second metaphase, which represent highly significant differences with regard to the expected frequency of balanced cells according to the metaphase I orientations (table I) (x 2 = 10.17, P = 0.001).

MoH/AA monitoring data found a highly significant response ( p < 0.001) for water treatment by December 2014 with a 50% increase (37 to 87%) before and after training which rose to 91%, before dropping slightly to 89% by 2017 (Table 5 ).