“highly significant”

The OR per standard deviation went from 1.75 to 1.44 as age increased from the 40s to 70s and that this trend was highly significant (p=3.44 × 10 −10 ) [ 152 ].

Linear regression analysis revealed a highly significant association between the number of siderophore loci carried by an isolate and its intracellular growth ( P = 3.51 × 10−10).

These two highly significant SNPs were rs1005277 near the ZNF25 gene (OR = 1.45, 95% CI, 1.29–1.62, p = 3.68 × 10 −10 ) and rs12417758 in a long non-coding RNA (lncRNA) gene, RP11-867G23.13 (OR = 1.22, 95% CI, 1.11–1.34, p = 3.66 × 10 −5 ).

We perform whole-exome or genome sequencing of 146 kindreds with sporadic (n = 138) or familial (n = 8) CFM, identifying a highly significant burden of loss of function variants in SF3B2 (P = 3.8 × 10 −10 ), a component of the U2 small nuclear ribonucleoprotein complex, in probands.

Furthermore, highly significant enrichments in biological functions have been observed to be related to the immune system; for example, inflammatory response ( P <3.84E10 −20 –1.53E10 −5 ), immunological disease ( P <8.93E10 −16 –1.65E10 −5 ), hematopoiesis ( P <3.09E10 −14 –4.98E10 −6 ) were frequently encountered.

However, linear regression analysis also demonstrated a highly significant overall correlation between cell loss and the vulnerability module scores (p-value = 3.89e-10), even when the input clusters were excluded from analysis ( Figure 6—figure supplement 1C ).

For the whole group of 253 students, the increase in net score means were 7.85% after SR, and 3.95% after CM; both were highly significant: P < 0.4 × 10 -9 for SR and P < 0.1 × 10 -3 for CM.

Finally, we found a highly significant overlap ( p = 4.08 e –10) of 20 DEGs between Mp spirrig and Atspirrig ( Supplementary Table S5 ).

Yield strength represents the stress required to initiate plastic deformation and is a key indicator of a material’s load-bearing capacity. Statistical analysis ( Table S3b ) again confirmed a highly significant effect of processing method ( p = 4.10 × 10 –10 ), but no significant effect of HEC concentration ( p = 0.925).

As a result, and despite the limited number of points in the regression, we obtained a highly significant negative correlation ( P = 4.1 × 10 − 10 and R = −0.99), as in the example in Fig. 2d –f.

Predictive value of the dichotomous score in risk subgroups When applying the cutoff defined in our previous study, PS29MRCdic was highly significant in the prediction of treatment failure (OR, 4.81; 95% CI, 2.95-7.93; P = 4.15 × 10 −10 ).

After this correction, residual SCC dissimilarity was still much higher for natural than for LL-synthetic stimuli and highly significant ( t test, P = 4.17e-10, t = 6.26, df = 7,468).

This enrichment was highly significant (OR, 227.55; 95% CI, 41.43–1,249.71; P = 4.23 × 10 –10 ).

Similarly, hypomethylation in PD cases can be observed for two highly significant CpGs in immune-related genes cg04772575 in ABCB9 ( p = 4.3 × 10 –10 ) and cg11334709 in C1orf200 ( p = 7.5 × 10 –10 ).

We also performed a Mann–Whitney U -test between the results of the two models that were highly significant, U = 2587.5, n1 = n2 = 56, p = 4.3 × 10 −10 two-tailed, median of the sensor model = 0.77, and median of the baseline model = 0.64.

6 d), with the TG association remaining highly significant even after adjustment for these metabolites (p = 4.4E−10).

This disproportion is highly significant statistically (χ 2 test, P = 4.4 × 10 −10 ).

This difference is highly significant ( P = 4.4 × 10 −10 in a one-tail z test).

GWAS Genome wide association analyses of IL-10 levels ( S3 Table ) resulted in one highly significant peak on chromosome 9 in the ACS patient cohort (top SNP: rs676457, P = 4.44*10 −10 ), and another borderline significant SNP on chromosome 6 in the healthy controls (rs11961593, P = 1.80 × 10 −7 ) ( Fig 1 ).

The other two highly significant markers 3173785|F|0–51:A > T-51:A > T on A09 ( -log 10(P) = 9.33) and 3105087|F|0–23:C > A-23:C > A on A09 associated with RE revealed normal monogenic segregation ratio ( χ2 : 4.08 to 4.38, P = 0.111 to 0.129) (Table S9 d).

The results suggested highly significant differences in KDM4A levels between normal mesothelial and MPM tissue specimens ( p = 4.74 × 10 –10 ).

Repeated measure ANOVA demonstrated a highly significant effect of the group factor (good/bad learners: F 1;36 = 85.3, p = 4.9 × 10 −10 ) and the effect of the sex factor (male/female: F 1;36 = 64.4, p = 1.5 × 10 −9 ) on the reaction time.

In the families, we obtained a highly significant result for the pathway of eight genes for the quantitative trait Q1 ( p = 4.9 × 10 −10 ).

Increases in the number of active licks across the test sessions was statistically highly significant [ F (1,19) = 133.5, p = 4.9 × 10 -10 ).

For peptides detected in both iTRAQ 4-plex as well as iTRAQ 8-plex labeled form, the median Mascot ions score was 53.9 for 4-plex and 45.6 for 8-plex, and a paired t test was highly significant at p < 5 × 10 −10 .