As shown, the OS difference between ARID1A‐loss GC patients with ACT and ARID1A‐loss GC patients without ACT remained highly significant after adjusting for age, TNM classification, grade, and TCGA subtype (TCGA: HR, 0.39, 95% CI, 0.22–0.71, p = 0.002, Table S7 ; ZSHS: HR, 0.07, 95% CI, 0.02–0.21, p < 0.001, Table S8 ).
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T-tests on changes from baseline show that, at all time points throughout the study, the HDL/TC improvement from baseline was highly significant (p < 0.002).
Cumulative disease burden (an approximation of lesion volume) on MRI showed a highly significant effect of high dose IFNβ-1b compared to placebo (p = 0.002).
In addition, the relationship between arm vascular conductance and deep venous plasma [ATP] during heating was highly significant ( r 2 = 0.49, P = 0.002).
In our study, we could see a highly significant rise in salivary ALP levels in gingivitis ( P =0.002**) and periodontitis patients (P=0.001**) as compared to the healthy controls [ Table 1 ], thereby, indicating the pathological changes occurring in the underlying periodontal tissues.
Highly significant improvements were found in sprint 1 ( p = 0.002, 95% CI [0.032, 0.132], ηp 2 = 0.195), sprint 2 ( p = 0.001, 95% CI [0.018, 0.064], ηp 2 = 0.029), sprint 4 ( p = 0.000, 95% CI [0.097, 0.225], ηp 2 = 0.353), dribbling layup time ( p = 0.009, 95% CI [0.019, 0.124], ηp 2 = 0.152) and total completion time ( p = 0.000, 95% CI [0.446, 0.785], ηp 2 = 0.366). 3.3.2.
Survival was lower, but not significantly so, in the STn-positive group (P = 0.07), but this effect was highly significant for patients with node-positive disease (P < 0.002), the curves for node-negative disease being coincident (P = 0.31).
Both current smoking rate and cessation rate remained to be highly significant even after controlling for age, education, occupation, and living apartment (p = 0.002 for current smoking rate and p = 0.004 for cessation rate).
However, between McGrath MAC and Macintosh and Truview and Macintosh groups, the difference was highly significant ( P = 0.002 for each).
Comparative analysis of these two pooled datasets showed a highly significant difference in insect feeding preference, with tissue infiltrated with non-trichome-inducing Agrobacterium strains preferentially eaten (P = 0.002, Student’s t-test) ( Figure 4B ).
A highly significant difference (p = 0.002) was present in the mean fear score concerning the number of family members with a higher score among those who had fewer than four family members (25.90 ± 5.91).
Nevertheless, the changes in the Fs-LASIK group are more predictable at 3 months postop, because the intergroup differences in the correlation coefficients for the J0 vector were highly significant (P=.002).
An interesting additional result of subgroup analysis was a highly significant difference between the patients who underwent resection after PET staging versus patients who underwent resection without PET staging (Fig. 4 , p =0.002).
Interactions between soil inoculum, inoculum sterilization, and seed type affect biomass A highly significant three-way interaction between inoculum origin, inoculum sterilization, and A. millefolium seed type ( Table 2 A; P = 0.002) ( Fig. 3 ) revealed a complex response of naïve and experienced A. millefolium to inoculum treatments.
The difference in the occurrence of systemic amyloidosis between the two groups was highly significant (25% of HP variants patients versus 0% of LP variants patients, p = 0.002).
A runs test ( Horn et al., 1984 ) shows that the grouping of channel activity is highly significant ( P < 0.002), even in this experiment where pulses were delivered at 5-s intervals.
Highly significant difference in muscle-epithelial distance was seen between controls as compared to early ( p -value =0.002), moderately advanced ( p -value = 0.001) and advanced OSF ( p -value = 0.001.
As can be inferred from the distributions shown as semi-violin plots in Figure 2 , this difference of 6.6% was statistically highly significant ( p = 0.002, one-tailed permutation test) and corresponds to a large effect size (Cohen's d = 2.96) demonstrating that an injection of ketamine indeed reduced susceptibility to the Chubb illusion.
Notably, 2 GOs of 111 gene sets, regulation of apoptotic signaling pathway and regulation of inflammatory response, were found to include 5 of those 14 genes and showed highly significant associations ( P = 0.002, Fig. 5 ).
The age and sex adjusted interaction between DM and CVD in predicting mortality was highly significant (p = 0.002) and persisted after accounting for comorbidities and treatment factors (p = 0.006).
Each comparison between adjacent deviant levels was also found to be highly significant (paired t -tests, P < 0.002 for all comparisons).
The gender check indicated a highly significant difference in wound infection in the male patients following fistulotomy with marsupialization procedure (10.1%) and conventional fistulectomy (24.1%) (p=0.002).
This between-group difference was highly significant ( p = 0.002) ( Table 2 and Figure 2 ).
Case–control differences in allele frequencies Apart from the highly significant lower B2 allele in the Chinese CAD + cases compared to the controls (p = 0.002), the allele frequencies for both the promoter and Taq1B polymorphisms are not significantly different between CAD + cases and controls in all the ethnic groups.
As shown in Figure 3 , in a PAR 2 -LRP6 co-transfected cells, SLIGKV peptide activationfor 5 min induces a highly significant ( p =0.002) maximal increment in BRET ratio.