The estimated coefficient of the PEV period (beta = 0.18, SE = 0.06) was highly significant (p = 0.003), indicating that the PEV period was associated with an 18 percentage-point increase in cases showing a >1 month lag in presentation to a health facility.
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The presence of significant arrhythmias in the first phase was associated with 5 times higher mortality, and even with this small study we were able to show a highly significant difference in outcomes. 19 This association was even stronger (HR = 6.04, p = 0.003) to the cumulative incidence of SCD and VT/VF events ( n = 12).
48% of subjects who rated their health as very good or excellent exercised regularly, while it was a much smaller percentage in the "poorer" group (5.6%), with an OR of 15.69 which was highly significant (p = 0.003).
Marked heterogeneity was observed with an I 2 value of 82.84% and a highly significant Q-test value of 11.66 ( p = 0.003), suggesting poor comparability between the different social skills measures used in the original studies.
The difference in methylation phenotypes between mice that had no past paternal transmission and those that did was highly significant (P<0.003; one-tailed Fisher's exact test).
Sample concordance between capture and indirect assays was highly significant (p = 0.003).
The deficiency of female fetuses was not statistically significant in the AI group (p = 0.20) but was highly significant in the IVP group (p < 0.003) when compared to the binomial distribution with the expected 1:1 sex ratio.
Relative AP threshold, defined as the difference between absolute AP threshold and resting potential, showed a highly significant negative correlation with mean AP frequency (Pearson’s correlation coefficient r = −0.41, p = 0.003; Figure 5 B).
After Holm correction for multiple comparisons, the between-group difference at the immediate postoperative time point (CrH0) reached nominal significance (adjusted p = 0.030), whereas differences at 24, 48, and 72 h were highly significant (CrH24: adjusted p = 0.003; CrH48: adjusted p = 0.002; CrH72: adjusted p = 0.002), suggesting that the divergence between MHR groups became more pronounced and sustained from 24 h onward.
The difference remained highly significant after adjustment for the other clinical variables listed in the Supplementary data online , Table S3 , with an odds ratio of 9.8 (95% CI 2.8–34; P = .003).
These three markers also showed highly significant associations with spot blotch resistance ( P = 0.003–0.006).
The effect of interaction by ejection fraction (EF) was highly significant: HF with preserved EF (≥40%) was significantly associated with inadequate FI with adverse outcomes (HR 4.95; 95% CI 1.71 to 14.36; p=0.003) but HF with reduced EF (<40%) was not (HR 0.77; 95% CI 0.31 to 1.95; p=0.590).
Differentiation in phylogenetic diversity was highly significant across groups (Faith’s PD, p = 0.003), with 32nd St being phylogenetically more diverse than all other sites ( p = 0.04), save for a marginal difference with Dalla ( p = 0.08).
1 upper), for all head pitch angles the mean responses were directed forwards with cathodal stimuli and backwards with anodal stimuli giving rise to a highly significant effect of polarity ( F (1,6) = 22.381; P = 0.003).
6 There was a highly significant strong positive correlation ( r = 0.655 and p = 0.003), confirming the role of placement support mechanisms in student satisfaction with their placement experience.
These associations were not affected when adjusting for smoking and duration of symptoms ( table 4 ) or in trend tests where the associations were highly significant (p=0.003).
This is a highly significant change ( p = 0.003, paired two-tailed t -test), and the difference from baseline after switch-on is also highly significant ( p = 0.008, paired two-tailed t -test).
trachomatis infection at multiple time points ( Table S2 ), and linear modeling of log 2 [IFNα2] with SNP and 70 h post-infection burden as covariates revealed the SNP effect was much larger (regression coefficient = −0.623 versus 0.017 for burden) and was highly significant, with a p value of 1.87 × 10 −13 (versus p = 0.003 for burden) ( Table S3 ).
CAEP Waveforms Figures 5A–C show exemplar sets of waveforms for three participants for whom both signals were audible at the initial test level (15 to 20 dB SL) and for whom all responses were highly significant ( p < 0.003) according to HT 2 .
The omega-3 index turned out to be a highly significant predictor of VF during the course of a first-time AMI with an OR of 0.42 (95% CI; 0.24–0.75, p = 0.003).
Using the mentioned macronutrients and questionnaire derived intake variables as covariates in the analysis of disease‐associated shifts in microbial beta‐diversity yielded no significant associations ( P > 0.05, respectively) and also revealed only minor effects on the still highly significant change in community composition associated with PSC ( P = 0.003, R 2 = 0.019). 4 DISCUSSION It is unclear, to which extent reported single centre microbiota studies in PSC were influenced by environmental factors and whether reported associations would remain significant across different geographical regions.
Repeated measurements on the extracted data show that there was a highly significant interaction between acupuncture mode (verum vs. sham) and time (across all three treatment sessions) for cortical thickness of left pMPFC (F(2,24) = 7.519, p = 0.003).
When we performed a bootstrap analysis with 10 000 repetitions of the difference in C statistics between the traditional risk factors and the model that included 5 metabolites together with the traditional risk factors, the mean difference across the subsamples was close to the calculation in the total sample, with a 95% CI being highly significant (bootstrapped mean C statistic difference between models 0.0391 [95% CI, 0.0134–0.0649]; P =0.003).
The difference between the two groups was highly significant, p = 0.003.
Meanwhile, there was a highly significant variation among different age groups (P < 0.003) ( Table 1 ).