“highly significant”

The estimated pooled OR for both 2 trials shows a highly significant reduction of the risk of recurrence for patients receiving adoptive immunotherapy (OR = 0.35; 95% CI, 0.17 to 0.71; p = 0.003; Fig. 2 ).

They proposed a quantitative parameter that characterizes this curve slope based on in vivo strain measurements, which showed highly significant ( p = 0.003) differences between rat models of acute bowel inflammation and chronic bowel fibrosis. 9 These US strain elastography findings have been translated to humans in 3 studies in a total of 40 CD patients scheduled for bowel resection.

Multivariate RDA analysis showed highly significant differences in microbiota composition at a phylum level ( P = 0.003) between the 4 groups with no significant difference by Salmonella ( P = 0.263) but with a significant effect of OA blend as a factor ( P = 0.014).

Interactions between sex and the age components transformed in the spline basis were introduced but only the parameter for the interaction with the third component was highly significant ( p- value = .003) and was retained in the final model (denoted by γ i ).

4 b), and a strong, highly significant negative correlation between peak firing rate and swap frequency (r = −0.41, p = 0.003; Fig. 4 c).

trachomatis infection at multiple time points ( Table S2 ), and linear modeling of log 2 [IFNα2] with SNP and 70 h post-infection burden as covariates revealed the SNP effect was much larger (regression coefficient = −0.623 versus 0.017 for burden) and was highly significant, with a p value of 1.87 × 10 −13 (versus p = 0.003 for burden) ( Table S3 ).

In female patients with breast cancer, there was a strong positive relationship and highly significant correlation between HMTV and BRCA1 as well as BRCA2 (r = 0.443, p = 0.003 and r = 0.58, p = 0.006, respectively; p < 0.01).

The association is highly significant ( x 3 2 = 19.5, P = 0.003).

parapsilosis isolates from RTT subjects induced highly significant levels of IL-10 compared to HC C. parapsilosis isolates and RTT C. albicans isolates ( p < 0.003, Wilcoxon rank-sum test; Fig. 3 ) suggesting an increased fungal tolerance towards these C. parapsilosis isolates, potentially favouring fungal persistence within the host.

Among the 663 patients with TNBC, pCR rates were 39.3% with bevacizumab vs 27.9% in controls, and the difference was highly significant (odds ratio [OR] 1.67, 95% CI 1.21–2.31, P =0.003).

The difference was highly significant between non-infected women and those with infection at the first trimester ( P = 0.003), while there were no differences when non-infected women were compared with infected ones occurring in the second and third trimesters (Fig. 4 C).

After the first interim analysis (performed, in accordance with the protocol after 40% (n=34) patients completed 6 months follow-up), the DSMB recommended to stop further enrolment as the analysis showed a highly significant result (p=0.003) in favour of the active treatment arm.

Notably, hiNs containing both RIN3 mutations (RQPS) showed a highly significant elevation in active RAB5* levels ( n = 3, P = 0.003) compared to the R427Q mutation, possibly synergistically, in the presence of the P477S mutation.

The effect of the odorous stimuli was, however, highly significant (GLMM, R 2 M = 0.10, R 2 C = 0.21, χ 2 = 13.618, P = 0.003) whereas we did not find a significant effect of season (χ 2 = 0.845, P = 0.358).

When these two variables were entered in a regression model, the overall model was highly significant [F(2,16) = 8.4, p = .003), explaining a large proportion of variance in social QoL (r 2 = 0.51).

We found that 18% of capsids were present outside RC-like inclusions in DMSO-treated cells compared to 6% in LatA-treated cells (3-fold decrease), and this difference was highly significant ( P = 0.003).

The difference in H o among the populations from the three zones was highly significant ( P = 0.003), as were differences for F is ( P = 0.002) and R elc ( P = 0.005).

Analysis of individual within-group activation revealed highly significant activation of the right hippocampus [ t (14) = 3.74, p = 0.003] and right parahippocampal gyrus [ t (14) = 3.51, p = 0.006] and significant activation of the left hippocampus [ t (14) = 3.21, p = 0.021]and left parahippocampal gyrus [ t (14) = 3.14, p = 0.014] in controls, again for the main effect of task.

The post-intervention program revealed a highly significant improvement (with a highly significant difference, p < 0.003) in HbA1c post-intervention levels, which showed a significant improvement among the study group compared to the control group.

When β-catenin expression was scored in these same colon cancers, a highly significant inverse correlation between the level of SIRT1 expression and nuclear β-catenin localization became apparent (p≤0.003, odds ratio 0.24 with 95% confidence interval 0.093–0.63) ( Fig. 5A, B ).

Comparison of individual groups with the control group showed that resistance, now highly significant at both radiation doses (P = 0.003), was confined to the mutation carriers (groups B and C).

While using the Cochran–Mantel–Haenszel test, which analyzes the correlation between the variables, the correlation appears highly significant (p = 0.003).

These three markers also showed highly significant associations with spot blotch resistance ( P = 0.003–0.006).

The level of statistical significance was set as follows: p > 0.050: not significant (NS) p < 0.050: significant (S) p ≤ 0.001: highly significant (HS) Results Upon comparing the demographic data of the two groups, a significant disparity was observed in sex, with a larger prevalence of men in group II ( p = 0.003).

As shown in Figure 6 , group B showed a highly significant clinical success IKDC score (p=0.003).