Both the EFS and OS were highly significant across the three risk groups ( p = 0.008 and p = 0.004, respectively).
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The association with ventricle laterality was highly significant ( P = 0.008): Looping class 4 is only associated with normal D-LOOP, as well as most of class 2 ( Fig. 1G ).
This also led to similar conclusions with a highly significant interaction between time and treatment for CFQ (p = 0.008) and similar estimates for change from baseline to 3 months (−5.5 [-10.1,-0.9] and −17.2 [-22.6, −11.8] in intervention and control group respectively). 5.
The difference in the short sclerotic line measured on the anteroposterior shoulder radiograph was highly significant ( p = 0.008), with 16.2 mm (range, 6.64–28.26) in the PASTA compared to of 13.1 mm (range, 8.27–23.87) in the BURSA group.
Highly significant simple principal effects of background noise [F (2,36)=4.73, p=0.008] and reverberation [F (2,36)=6.31, p=0.006] were observed.
Results A highly significant association was found between the homozygous CXCR2 (+ 1208) TT genotype (adjusted OR = 2.89; P = 0.008) and breast carcinoma.
Here, we found a highly significant effect of reward [ F 1,19 = 8.86, p = 0.008], indicating that subjects were more likely to sustain effort in the late reward period when a high, as compared with a low, reward was at stake (placebo: t 19 = 3.68, p = 0.002; levodopa: t 19 = 2.87, p = 0.010; haloperidol: t 19 = 1.87, p = 0.076).
Two-way ANOVAs revealed a highly significant FEMALExSTIMULUS interaction in almost all the regions analyzed: PrL-IL (F 1,26 = 8.341, p = 0.008; see Figure 3 A); BLA (F 1,26 = 23.660, p < 0.001; Figure 3 B); AcbSh (F 1,26 = 18.882, p < 0.001; Figure 3 C); AcbC (F 1,26 = 56.418, p < 0.001; Figure 3 D); VTAp (F 1,26 = 15.897, p < 0.001; Figure 3 F).
Corresponding to the results from the TCGA cohort, we found that the deep stroma score was a highly significant prognosticator for OS (HR 1.63 [1.14–2.33], p = 0.008), DSS (HR 2.29 [1.5–3.48], p = 0.0004), and RFS (HR 1.92 [1.34–2.76], p = 0.0004) in these patients ( Fig 6 ).
By the period of 2004–2008, significant RER’s continued to exist for, stomach, colorectal, liver, lung, breast, prostate cancers, while RER variations in cervical and uterine cancers became highly significant ( p = 0.008 and 0.001 respectively).
Quantification of TLR4 transcripts in PBMCs exposed to 50 μg/ml of ES for 2 h (ES 50 2 h) showed a highly significant up-regulation ( P =0.008) ( Fig. 1B ).
Influence of associated cofactors on the outcome The comparison of the average initial displacement of fractures with good and poor radiological results shows a highly significant difference (11.4mm (0-39mm) vs. 17.8mm (8-37mm), p = 0.008).
With HCs and SRs pooled together, the association of D5 and chronic HBV infection was highly significant ( P = 0.008, OR = 2.81, 95% CI = 1.32–6.00) (Table 3 ).
However, there was a significant increase in the progress of audits whose durations extended to more than 6 months (p = 0.024) and a highly significant association for those carried out for longer than one year (p = 0.008).
Interestingly, despite the fact that the actual target of selection is not known, the clinal frequency change is highly significant ( p < 0.008) based on Student’s t test for 10,000 random sets of SNPs generated by jackknifing 21 SNPs out of the 197 SNPs segregating in the region of interest (3R: 4,239,638-4,271,390, Additional file 1 : Figure S15).
The mean baseline acuity was 20/494 (log Mar=1.338±0.455) and the mean acuity at three months following the second intravitreal injection was 20/295 (log Mar=1.094±0.254), a difference that was highly significant ( P =0.008).
There was a highly significant ( P = 0.008) improvement in survival on day 180 in the day 1–3 plus day 31–45 treatment groups (60% versus 10% in the control group).
Finally, during the follow-up, the frailty index in the intervention group was 1.80 ± 1.13, whereas it was 3.08 ± 1.19 in the control group, with highly significant differences ( p = 0.008**).
Further decomposition of factor effects revealed that differences among the three plots (R, S, and W) had a highly significant influence on community variation ( R 2 = 11.89%, P = 0.008), indicating substantial differences in community composition between the R, S, and W blocks.
While none of the tests returned correlations above 0.3, we can see that (throw) came the closest with 0.220 (and also showed a highly significant correlation with p = 0.008) followed by (our), r = 0.203, p = 0.015).
A highly significant difference (TOC higher when compared to TATE) was found for primary tumors ( P = 0.008), liver ( P = 0.000) and lymph node ( P = 0.000) metastases, while uptake of 68 Ga-DOTATOC was significantly higher in bone metastases ( P = 0.011).
However, a similar association with changes in CSF anti-IgLON5 IgG4 was highly significant ( p = 0.008, Figure 4C , right panel), confirming CSF anti-IgLON5 IgG as the major influence on zQ IgLON5-IgG4 .
The increase in the risk of a second generation is highly significant (Wilcoxon rank-sum test, n = 10, W = 19, P = 0.008).
Strikingly, this neural dissociation between threat levels showed a highly significant relationship to both subjective anxiety reports during the task ( r = .552, p = .008) and trait anxiety ( r = −.503, p = .017) in female participants, but not in male participants ( r = −.082, p = .753 and r = −.290, p = .259, respectively).
In post hoc secondary analyses, similar results were found using ANCOVA with baseline score as covariate, except that the difference between groups in SPARCC MRI spine index (23-DVU) at week 6 was highly significant when using ANCOVA (P=0.008) ( figure 3 ).