Highly significant differences were seen in plasmacytoid DCs (pDCs) (mock primed: 56.4±1.6; ArmΔGPC primed: 30.2±1.7, p = 0.00003), macrophages/monocytes (mock primed: 11.4±1.6; ArmΔGPC primed: 2.1±0.6, p = 0.0017) and FRCs (mock primed: 9.0±0.4; ArmΔGPC primed: 1.7±0.3, p = 0.000007) from primed and mock primed Cl13 infected mice ( Fig. 6A ).
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In all cases, there was a clear bias of propagation in one orientation, which was highly significant ( P < 3 * 10 −5 ; 12 retinas aged P4–6; data not illustrated).
Furthermore, we also confirmed there was a highly significant correlation between MM and GS in this module (Cor = 0.47, p =3 e − 05) ( Figure 3(d) ).
Within the case group, a Jonckheere–Terpstra test for trend (based on 100,000 permutations) revealed a highly significant increasing trend across the three age strata (puppy, juvenile, adult; JT = 166.5, p = 3 × 10 −5 ) with the median VBI increased from 0.48 (puppy) to 0.55 (juvenile) and 0.57 (adult).
Symptom prevalence The most frequently reported symptom among patients with uterine isthmocele was AUB, observed in 45 cases (78%), which showed a highly significant association (p = 0.00003).
The dust sheet test 2–3 h showed the highest correlation with the reference method with the data points scattered closely around the regression line and the slope being highly significant ( p = 0.00003).
When we compare SO 2 values with HbO 2 double peaks the difference was highly significant ( P = 0.00003).
The difference in the GPi cell firing frequency across the groups was highly significant ( figure 2 C p=0.00003).
This highly significant enrichment of S-aromatic motifs within the low-reactivity group (p-value = 3 × 10 −5 ), allows us to conclude that the involved methionines exhibit a much lower reactivity than their non-interacting counterparts.
In particular, CM-CF showed highly significant differences compared with U-CF ( P value = 0.00003), indicating a positive effect of the combination of mercerization and coating on CF stiffness.
This difference is highly significant ( P = 0.00003), calculated using a χ 2 test. 10 Financial disclosures are summarized in Table 1 .
In these pairs, a slightly smaller but still highly significant difference was found, again with the luteus coding sequences associated with higher redness ( t = 4.4855, df = 65, p = 3.03 × 10 −5 ).
Serum FSH was elevated about two-fold (from 88 to 208 ng/ml) with a highly significant p-value (p = 3.07 x 10 −5 ), and LH was elevated about eight-fold (from 0.35 to 2.6 ng/ml), also with a significant p-value (p = 0.014; Fig 10C and 10D ).
In ER-positive patients, highly significant differences between patients with high vs. low CYP19A1 expression were observed with respect to OS ( P = 3.1 × 10 −5 ; Fig. 4 d), DFS ( P = 2.1 × 10 −4 ; Fig. 4 e), and MFS ( P = 1.5 × 10 −6 ; Fig. 4 f).
4a , the difference between groups was highly significant (Kruskal-Wallis, P = 3.107e-05).
This represents highly significant enrichment compared to such variants from gnomAD v2.1 (23 of 958 variants; one-sided Fisher’s Exact Test p -value = 3.15 × 10 –5 , odds ratio = 39.8).
By the 45th day, the group administered with a low dose exhibited significantly elevated L-carnitine levels relative to the control group ( p = 0.0129), whereas the high-dose group not only exceeded the low-dose group ( p = 0.013) but also demonstrated highly significant differences to the control group ( p = 3.15 × 10 −5 ). 3.2.
In the itpr mutant condition 50 down-regulated genes cluster in the mitochondrion ( Fig 2 ; CC) and a highly significant number (P = 3.2E−5) have the molecular function (MF) of oxido-reduction.
The assigned thresholds were then validated by examining the association between immunostaining scores of the HER-2 gene (HercepTest, DAKO, DK-2600, Glostrup, Denmark) and copy number states, that is, gains, no change and deletions, which was found to be highly significant (Pearson's correlation, r = 0.53, P = 3.2 × 10 -5 ).
The difference of S nontrem between pretreatment (−0.097) and at 4 years and beyond (1.197) was highly significant ( p = 3.22e‐05), whereas that of S trem was not (0.017 vs. 0.068; p = 0.73).
The difference is highly significant ( P = 3.3 × 10 −5 , Poisson distribution).
This highly significant overlap (odds ratio = 45.9, P < 3.3 × 10 −5 , permutation test, 30,000 times) provides an independent confirmation of our results.
Nevertheless, the association of rs1363713 with AF trait was highly significant ( P =3.34 × 10 −5 ), but not as significant as the CNV.
When the number of trophic niches occupied by members of clades was used in this model in place of the number of habitat types, we again found a highly significant result (multiple PGLS, p = 3.365 × 10 −5 , F = 14.62 on 2 & 29 d.f., adj.R 2 = 0.4523, N = 34).
rubidus collected from dung quadrats than those lacking dung, a highly significant difference ( p = 0.0000339, W = 4.15, df = 1, p < 0.01).