“highly significant”

In addition, a highly significant association ( p <0.0001) was observed between weight gain and the number of cigarette-free days.

The enrichment of the identified proteins with oxidoreductase activity or involvement in cell redox homeostasis as determined using the ProfCom database was statistically highly significant (p<0.0001).

All group comparisons were highly significant ( p <0.0001).

Differences in VSRQ scores across clinical severity groups were highly significant (p < 0.0001).

As shown in Figure 4 b, analysis of the GAAATT motif in the promoters of these genes by POBO shows that enrichment of this motif is highly significant (p-value < 0.0001) [ 31 ]. qPCR confirmed that expression of all cluster members was induced in response to infection with Pma ES4326, this induction was significantly suppressed in the cbp60g sard1 mutant for AGP5 , At5g52760 and CML47 ; CML46 expression was lower in the double mutant but with a high p-value of 0.097 (Figure 4 c).

This was supported by highly significant group × trial interactions (path lengths: F 160,3360 = 1.69, p < 0.0001; search preference: F 40,840 = 2.28, p < 0.0001).

For human genes, highly significant differences were found between G1 and G2 (F = 1.29; p <0.0001), G1 and G3 (F = 1.33; p <0.0001), or G1 and G4 exons (F = 1.33; p <0.0001), while none was found between G2 and G3 (F = 1.04; p = 0.4254), G2 and G4 (F = 1.03; p = 0.4285), or G3 and G4 exons (F = 1.00; p = 0.9243).

Mc Neman concordance between tests P < 0.0001 and Kappa index gives us a highly significant concordance P < 0.0001.

Highly significant improvements (p < 0.0001) were noted on all efficacy measures over the study period.

Through statistical analysis using Student’s t-test, we observed highly significant differences in anti-Xa assay results between bleeding and non-bleeding groups ( p < 0.0001) at both peak and trough times.

To test for the scalar invariance of the controlling-behavior items, the ∆CFI between the configural model and the scalar model was not within its recommended range of ≤ 0.002 [ 34 ], and the χ 2 difference test comparing the nested scalar model with the configural model was highly significant, at p <.0001.

All these effects were highly significant (p < 0.0001).

Moreover, the study revealed a highly significant correlation between SNOT-12 and SNOT-22 ( P = .0001).

In this analysis, group differences in subjective pain scores were highly significant before controlling for the effect of anterior cingulate cortex activation ( F = 38.0, P <0.0001); a finding that was reversed ( F = 1.8, P = 0.195) when removing (regressing out) this effect.

The correlation between CXR results at autopsy and gross lung PA scores as calculated by non-parametric Spearman's rho (Rs) was strong (Rs = 0.75) and highly significant (p<0.0001) ( Figure 4A ).

Both of these variables were highly significant predictors of BU (p<0.0001).

The difference between the frail group and the others is highly significant [ p < 0.0001 by Mann–Whitney U -test (MWU)].

These trends, for both stage and grade, were highly significant ( p <0.0001 and p <0.0001, respectively).

The TMAO concentrations showed a highly significant difference between patients with CKD and healthy controls ( p < 0.0001).

While there was a highly significant main effect of dose (F[2,153] = 30.2; P <0.0001; Figure 2F ), there was no main effect of genotype (F[2,153] = 0.045; P = 0.96), nor was there an interaction between genotype and dose (F[2,153] = 0.085; P = 0.99).

A Mantels test for matrix correspondence between pair-wise genetic ( D AS ) and geographic distance (km) revealed a highly significant positive correlation between these two measures (R XY = 0.394, p<0.0001, Figure 3 ).

In fact, it was observed a highly significant (p < 0.0001) difference between the controls and MM or between MGUS and MM, while no significance was found between controls and MGUS groups (p = 0.95) by means of a two by two comparison of the three groups (controls, MGUS and MM) concerning the distribution of K- ras gene mutation, Interestingly, significant increases (P = 0.02) of serum bFGF levels were observed in patients showing K- ras gene mutation (median = 4.6 pg/ml; range = 1.2–19.6 pg/ml) as compared with those in which the gene was in the wild type form (median = 2.2 pg/ml; range = 1.0–20.8 pg/ml).

The differences where highly significant in the Wilcoxon test (z = -3,79; p < 0,0001).

In subadult and adult females, after the upward trend from the 1980s to 2010s, the decrease in body mass in the 2020s was less pronounced than in males but still highly significant (F 4,846 = 12.8, p < 0.0001 and F 4,1029 = 4.6, p < 0.002, respectively).

Similarly, all non-constant terms in a cubic regression of onset age on number of repeats were highly significant (p<0.0001), and the overall F-test for comparing the cubic model to a constant-age-of-onset model had a p-value of 4.4e-15.