“highly significant”

The average angle variance between the fibers from both groups was highly significant (p value < 0.0001), suggesting that TGF-β activated the LX-2 cells to successfully remodel and align collagen fibers as seen in ECM dense fibrotic tissues ( Baiocchini et al., 2016 ; Lee and Friedman, 2011 ).

Using physical exposure as a continuous variable, the exposure–response association was highly significant (trend test p<0.0001).

The main effect of domain was not significant (F(1,156) = 0.44, p = 0.51, partial_eta 2 = 0.0027), but the main effect of method was highly significant (F(1,156) = 57.51, p<0.0001, partial_eta 2 = 0.2610), and the 2x2 interaction also came out significant (F(1,156) = 5.9, p = 0.0163, partial_eta 2 = 0.0349).

Across nine sessions over three weeks, PBMT-sMF treatment led to a highly significant reduction in tender points and improved clinical impact scores ( p < 0.0001), with no adverse events.

The model is highly significant ( F 74/45 = 2.86, P = 0.0001, r 2 = 0.824), yielding a grand mean RR = 1.97 cM/Mb (Table S9).

All these final selected variables showed a highly significant negative relationship with the infection rate (p < 0.0001; Tmin r = − 0.25, AP r = − 0.23, RH r = − 0.21).

Highly significant differences ( P < 0.0001) could be determined between three sampling time points: preoperative, postoperative after clinical improvement and after six months and in comparison to the healthy control group (animal experiment number: 33.8‐42 502‐05‐18A290).

Cox regression detected a highly significant constant temperature effect on post-storage germination (Wald χ 2 = 36.69, p < 0.0001).

Correlation between profiling and individual qPCR technical validation for three miRNAs in the top 50 was highly significant ( p < 0.0001; R squared between 0.6344 and 0.8644; Supplementary Figure S1 ).

The correlations between R-values for filaments of different sizes, as well as between gratings of different sizes, were positive and highly significant ( p < 0.0001).

It can be seen from Table 2 that the selected model was highly significant ( p < 0.0001).

Note that all these correlations depicted in Figure 5 were statistically highly significant (all p < 0.0001).

At 3 months the Kruskal–Wallis test indicated a highly significant difference among treatment groups (Kruskal–Wallis H 3 = 23.42; 4 groups, n = 32, p < 0.0001).

Keywords Femoroacetabular impingement hip hyaluronic acid viscosupplementation Particularly, the slopes with respect to time for the variables VAS, HHS, Lequesne ( Figure 4 ) and NSAIDs monthly intake ( Figure 5 ) were highly significant ( p < .0001; p < .0001; p < .0001; p = .0003).

This was tested, with the results presented in Table 4 , where the likelihood ratio, score and Wald tests were all highly significant ( p -value < 0.0001), which means that at least one of the parameters is not equal to zero.

A paired t -test across languages showed that, in both cases, the difference was highly significant in the predicted direction ( p < 10 −4 ).

Furthermore, when this was combined with pre-treatment of cells with cisplatin, the correlation became stronger (median R = 0.70) and this change was statistically highly significant ( P -value < 0.0001; Figure 7A ).

Although differences in peak glucose time were observed (30 min for capillary blood and 45 min for CGM), the correlations between capillary and CGM values at both 30 and 45 min were strong and highly significant ( r 2 = 0.728 and r 2 = 0.806, p < 0.0001, respectively).

These results are further corroborated by a meta-analysis carried out by the Cholesterol Treatment Trialist’s Collaboration, in which more versus less intensive statin therapy was associated with a highly significant 15% (95% CI = 11 to 18; P <0.0001) further reduction in major vascular events [ 6 ].

Only regions that showed a highly significant univariate heritability ( h 2 SNP p <0.0001) for both schizophrenia and the cardiac trait were tested for local genetic correlation.

The concordance between direct microscopy and culture was highly significant, moderate for dogs ( p < 0.0001; kappa value: k = 0.53), but highly significant and perfect for cats ( p < 0.0001; k = 1.00) ( Table 1 ). 3.3.

From a quantitative standpoint, the ANOVA test showed a highly significant difference among groups for the overall scores (F = 19.14, p < 0.0001).

7 A), a remarkable and highly significant increase in NfL levels was observed in the PTX group ( P < 0.0001) and this increase persisted after 2 weeks of follow-up (Fig. 7 B) and until the end of the follow-up period (Fig. 7 C) ( P < 0.0001 and P < 0.05, respectively). 3.7.2.

There was a highly significant ( p = 0.0001) decrease in reticulated hemoglobin level in anemic patients of both sexes, in comparison to non-anemic patients, but the reticulocyte count did not show any significant difference.

Based on the hypothesis that the response to radiation could associate proteins or p-sites involved in the same molecular pathway, we submitted all statistically highly significant candidates (R>0.5 or <-0,5 and P<0.0001) to STRING analysis 30 .