“highly significant”

The analysis revealed that TSV induced less than 5% toxicity at 0.05 μg/mL, while toxicity exceeded 98% at 100 μg/mL, with a highly significant increase in toxicity across concentrations ( p < 0.0001).

In addition, when comparing delta values of both groups, we observed in MTZ-treated patients a highly significant reduction (i.e., clinical improvement) for both RCSS ( p < 0.0001, Mann-Whitney; Fig. 4 b) and MBAS values ( p < 0.0001, Mann-Whitney; Fig. 4 d) with respect to the untreated group.

Moreover, our results showed that the overall average resistance of Salmonella isolated from M-hatcheries was higher than that of L-hatcheries ( p = 0.0013), while statistical analysis performed by using two-way ordinary ANOVA, showed that the difference in resistance to the individual antimicrobial was statistically highly significant ( p < 0.0001) ( Figure 3 ).

The father-offspring correlation was highly significant (P < 0.0001), in contrast to mother-offspring (P < 0.361).

Interestingly, our formulation was capable of inducing a 1.65-fold higher immune response in rabbits than in cattle (i.e., a 65% increase); this difference was highly significant (p<0.0001; Figure-3a and b ).

A chi-square test comparing these seven entirely non-compliant staff to the 705 who wore at least one protective item yielded a highly significant result (χ2 = 684.28, p < 0.0001), indicating that complete non-compliance was far less common than expected by chance.

Also, a highly significant positive correlation ( p value <0.0001) between IV and PUFAs (Linolenic (C18 : 3) ( r 2 = 0.990) and Linoleic (C18 : 2) ( r 2 = 0.994)) was observed.

Exercise tolerance There was a highly significant variance in the exercise duration (expressed as percent compared to baseline) in the five groups (F = 93.3, P < 0.0001, Fig. 5 ).

There was a highly significant correlation of serum and saliva scores ( P < 0.0001) and the Spearman correlation coefficient of ρ = 0.602 indicated a moderate positive correlation [ 34 ].

Using a DD of 0.1 μg/ml of TBZ in the EHT seems a good alternative to the in vivo method since the levels of resistance measured by both tests were quite similar and comparable in our study, with a highly significant level of correlation ( r = 0.77; P < 0.0001).

Conversely, TSH and Cys-C showed a highly significant positive correlation ( p < 0.0001; Figure 2 d).

In Tg mice treated with LM11A-31, no difference in spine density between Tg and Ntg mice could be detected in either apical or basal spines, consistent with a highly significant drug effect (p < 0.0001).

The mean severity of glistening based on subjective assessment was 0.57 ± 0.60 in the Z-Flex, and 1.82 ± 0.90 in the Acrysof IQ group, and the difference was highly significant (p<0.0001).

The interaction between the time course and genotype was highly significant (p≤0.0001), the effect of genotype alone was also significant (p = 0.0026) ( Fig 6F ), and in post hoc tests multiple time points differed between heterozygotes versus homozygotes.

Gender was highly significant for all tested beverages ( p < 0.0001), with women consuming fewer alcoholic beverages than men.

The difference in agreement between the two conditions was highly significant ( t ⁢ ( 198 ) = 22.28 , p < .0001 , d = 3.15 ).

Effects on Periodontal Clinical Parameters As seen in Table 2 and Figure 2 , oral hygiene instructions led to a highly significant decrease of PISA and mean BOP (%) values ( p < 0.0001) in former and non-smokers but in not in current smokers ( p = 0.94).

The linear regressions between the available energy and the measured energy fluxes were all highly significant ( P < 0.0001).

These effects were highly significant when compiled across multiple experiments ( Fig. 3 C ) ( P < 0.0001).

The improvement with training from the first two sessions (0.75) to the last two sessions (0.83) is highly significant ( p < 0.0001).

The interaction effect between them was highly significant ( p ≤ 0.0001).

Most importantly, the LC3-II/LC3-I ratio, which measures autophagy activity, showed a highly significant increase in the iridocorneal region of the aging mice ( 4 months: 1.106 ± 0.21, n = 5; 18 months: 2.178 ± 0.10, n = 4; P < 0.0001, t -test) ( Fig. 2 C).

Nonparametric one-way ANOVA with repeated measures design by ranks (Friedman tests) revealed highly significant changes during the oGTT (AcG: p < 0.0001; UnG: p = 0.0007; ratio: p = 0.0087), but as specified by post-hoc Dunn’s Tests, in contrast to our expectations, we did not observe a strong decrease in circulating ghrelin levels after glucose ingestion.

500 nM Aβ 1–42 ), 23.1 ± 2.4% (mean ± SEM; n = 23) of wild type dendritic spines were associated with amyloid-β-immunoreactive puncta, whereas in contrast spines from p75 NTR ko neurons showed a colocalization ratio of only 6.9 ± 1.1% (mean ± SEM; n = 24), a difference that was statistically highly significant (p < 0.0001).

Moreover, the effect of anticoagulation became more pronounced when we analyzed single miRNA ∆Cq levels over time ( Figure 3 B), resulting in a highly significant ( p < 0.0001) difference between CTAD and EDTA plasma for the miRNAs miR-191-5p, miR-320a, miR-126-3p, and miR-21-5p.