“highly significant”

The measure of population differentiation, F ST , among the subgroups was 0.15 highly significant at P < 0.0001.

For the primary variable GIS the difference between placebo and verum after 28 days of treatment showed a highly significant (p < 0.0001) difference between placebo and verum (6.7 resp. 4.7 points).

While this makes logical sense, a closer look at table 2 and figure 3 shows that global longitudinal strain (GLS) has a highly significant correlation (r = 0.61, P = .0001).

The association between mortality and socioeconomic patterns was highly significant ( p -value <0.0001).

The overall KMO values (ranging from 0.53 to 0.64) were within the acceptable range for EFA in exploratory environmental studies, and Bartlett’s test was highly significant ( p < 0.0001), indicating that the data were appropriate for factor extraction.

A highly significant correlation ( ρ 0.43, p < 0.0001) between cyclin D1 mRNA and protein expression has also been reported [ 29 ].

The separation in the survival distributions for those with perfusion defects and those without perfusion defects was highly significant (log-rank p = 0.0001).

Quantification of Gag clusters at the ventral PM of DMSO (n = 27) or rCD1 treated (n = 26) cells revealed a pronounced (80%) and highly significant (p<0.0001) reduction of Gag clusters in PM PI(4,5)P 2 depleted cells compared to control cells ( Figure 1F ).

According to analysis of inferred metagenomic functional content using PICRUSt algorithm, a highly significant discrepancy in metabolism and immune functions ( P < 0.0001) was predicted in the obese group.

Two-way ANOVA showed that both HLA-DRB1*01 and HLA-DRB1*03 were associated with anti-CII levels (p<0.0001 for both), with a highly significant interaction (p<0.0001).

Although there were no significant across population differences in mean observed heterozygosities (Ho) in both years (Friedman test: χ 2 0.05,5,17 = 5.662 , P = 0.340 for yr 1; yr 2 was similar), differences in allele composition and manner of pairing were evident from the highly significant genic and genotypic differentiation all P << 0.0001 .

All other comparisons between treatments across species are highly significant ( t 72 > 5.492, p < 0.0001).

In contrast, zoledronic acid exhibited highly significant correlations for cell inhibition and TNF-α stimulation (r = 0.454, p < 0.0001), cell inhibition and RAP1A inhibition (r = 0.556, p < 0.0001), and TNF-α stimulation and RAP1A inhibition (r = 0.499, p < 0.0001).

This difference was found to be highly significant ( χ 2 = 285.32, p < 0.0001).

As illustrated in Figure 1B , in the mixed ANOVA run on mean correct RTs, the critical interaction between alignment and congruency was highly significant, F (1,127) = 14.6, p < 0.0001, η 2 = 0.10, MSE = 174.

Variance analyses showed that the effects of population, photoperiod treatment and population × photoperiod treatment interaction on days to bolting, days to flowering, rosette leaf number, and flower stem length were highly significant ( P ≤ 0.0001; Supplementary Table S2 ).

In the overall analysis of patients who received MPS and IVMP, there was a highly significant difference (3.9 ± 1 vs. 2.4 ± 1 p < 0.0001).

A highly significant stimulatory effect on the number of buds per polyp was observed under increasing feeding regimes in both species ( A . coerulea : F (2, 168) = 223.21, P<0.0001; A . relicta : F (1, 158) = 130.39, P<0.0001; Table 2 ).

The MANOVA test (Table 2A ) yields a highly significant p-value for both the 2 independent variables (p < 10 -4 ).

In rats (n = 4), four out of five studies with one study reported on VLDL level instead of LDL level, reveal a highly significant reduction in LDL (SMD = − 4.847, p < 0.0001) and CI for this effect ranges from − 5.693 to − 4.002.

The logistic regression model was highly significant (p < 0.0001, R square = 0.1).

When the two time curves were compared over the period 0–16 h, differences determined by two-way ANOVA were highly significant (p<0.0001); Figure 2B shows the significances of the differences in cell death determined after 2 h of observation using multiple comparison two-way ANOVA (p<0.0001: control/Vac; p<0.0001: Vac/Vac+ATP).

Both platform and nozzle temperatures were highly significant ( p < 0.0001), and multiple interaction terms (X 1 X 2 , X 1 X 3 ) were significant, demonstrating a non-linear coupling between thermal boundary conditions and dose accuracy.

For the northern strain, the analyses showed a highly significant dependency of diapause on day length, when different constants were estimated for each T-cycle treatment (Fig. 2 a, b; n = 24, df = 18, dev. = 103.79, p < 0.0001).

Both discriminant functions resulted to be highly significant (P < 0.0001) and the percentage of variation accounted for by the first discriminant function was 63.6% of the variance in the grouping variable.