Superoxide dismutase, glutathione peroxidase and catalase activities were highly significant ( p < 0.0001) in the treatment groups compared to the control.
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Highly significant correlations for GPI-AP deficiency were found within one cell lineage ( r 2 = 0.61–0.95, p < 0.0001) and between the different cell lineages ( r 2 = 0.49–0.88, p < 0.0001).
In contrast, PD-1 blockade resulted in highly significant tumor growth delay ( p < 0.0001) in all mice bearing Nedd8 KO EO771 tumors (Fig. 6b ).
There was a highly significant correlation between baseline and P3 ( p < 0001).
For logistic regression, both HC1 (estimate: 0.631, SE: 0.117, p < 0.0001) and HC2 were highly significant (estimate: −0.686, SE: 0.097, p < 0.0001).
The Q-test for heterogeneity was highly significant (P<0.0001).
This revealed a highly significant interaction [ F (4,240) = 26.42, P < .0001], indicating that the lateralization of shared processing depends on frequency band ( Fig. 2 ).
Attending to their age we can consider two groups, one comprised by those with ages under 40 ky (R0, R5, R7 and R8) and the other with ages above 40 ky (R6, R30, R31, U, JT) with highly significant differences ( p < 0.0001) between the mean age of each group, 36.8 ± 1.59 and 53.4 ± 2.69 ky respectively.
The high chi-square value indicating a highly significant association (p < 0.0001) between the two variables.
Our results showed a highly significant anti-correlation between CD2AP and Synapsin-1 (p < 0.0001, Figure 7D ), and other human Synapsin paralogs ( Figure S11 ).
This improvement was highly significant ( P < 0.0001).
This effect was not seen in Ewing's sarcoma; ch14.18/CHO had minimal cytotoxicity at the same concentration against Ewing's sarcoma irrespective of GD2 expression; the difference between the killing of Kelly or LAN1 and GD2 bright DC-ES6, was highly significant ( p =<0.0001).
A Hotelling’s T 2 test confirmed that this difference was highly significant ( T 2 = 685.25, P < 0.0001).
Statistical analysis using the Student’s t -test for related samples showed a highly significant difference between pre- and post-test scores ( p < 0.0001), indicating a strong effect of the intervention on stress reduction.
With regard to the relationship between mismatch repair (MMR) status and cancer stage, this was associated with a highly significant difference in stage distribution between dMMR cases ( n = 148) and all MMR cases ( n = 893) ( χ 2 (4) = 38.25, p < 0.0001).
Using a degree‐constrained method of permutation to test the null ( H 0 ) versus alternative hypothesis ( H 1 ) of whether the number and degree distribution of disease‐causing genes account for the number of disease subnetworks, in each case the observed number of disease subnetworks is highly significant ( P < 10 −4 ; Supp.
At the level of Ct values of our extraction methods, a highly significant, very strong positive correlation was demonstrated between the miRNeasy kit and the TRIzol and Universal kits (miRNeasy/Universal p < 0.0001, r = 0.980; TRIzol/miRNeasy p < 0.0001 r = 0.959), and a highly significant, very strong positive correlation was found between the TRIzol and Universal kits (TRIzol/Universal p = <0.0001, r = 0.965) ( Figure 3 ). 3.2.
Both of the main effects, sample and clone, are highly significant (both P < 0.0001).
This interaction between potato type and combination status was highly significant ( p -value < 0.0001); mixing potatoes with MPACs leads to increased MPAC consumption when the potato type is the shaped potato face, but leads to decreased MPAC consumption when the potato type is diced potatoes.
The model exhibited a highly significant fit, with an F -value of 452.49 and a P -value < 0.0001.
With respect to X 0 , all variables were highly significant (P < 0.0001) and were therefore included in the final model (detailed in Supplementary information: model outputs).
The difference is highly significant using the Wilcoxon signed-rank test (Bonferroni corrected, p<0.0001).
Results Our data showed strong, highly significant correlation between arterial and peripheral venous lactate levels (r = 0.880, P < 0.0001), between arterial and central venous blood lactate (r = 0.898, P < 0.0001) and between central and peripheral venous blood lactate (r = 0.941, P < 0.0001).
This highly significant increase (ANOVA, p < 0.0001, followed by a Tukey-Kramer HSD) in the total number of niche cells in the absence of an increase in the number of S phase cells, may also suggest that the 1 st -generation neuronal precursor cells in the crayfish niche are not self-renewing because their numbers can increase without additional cell divisions among the niche cells.
The two primary questions that we addressed in this study were (1) are there differences in the relative expression among the five AQPs within the amnion and (2) do AQP mRNA and protein levels correlate with IMA rate when IMA rate is experimentally altered? With respect to the first question, the recalculation indicated that in the control group, the highly significant difference in AQP mRNA levels ( P < 0.0001) remained with the added result that the difference in mRNA levels between AQP3 and AQP9 reached statistical significance.