“highly significant”

S2 , where we show that the number of gene pairs remaining after thresholding the ASD list (1168 gene pairs) is highly significant ( p < 10 −4 ).

The effect og age on mortality was highly significant, as only 10/538 deaths occurred below the age of 42, as opposed to 67/528 above the age of 42, p = 0.0001.

Results The logistic regression model used to predict the lifetime diagnosis of hypocalcaemia in adults with 22q11·2DS was highly significant (likelihood ratio test: χ 2 = 38·2, df = 7, P < 0·0001).

The Role of HSP70 in ADC and SCC Patients' Diagnosis In this study, we analyzed the role of HSP70 in adenocarcinoma (ADC) and squamous carcinoma (SCC) patients' diagnosis; the results indicated that plasma HSP70 levels of ADC and SCC were highly significant lower than that of the healthy controls ( P < 0.0001) ( Figure 2 ).

The intra-subject repeatability of the sputum calgranulin A/B was highly significant (p <0.0001).

The results revealed considerable heterogeneity ( I 2 = 80.93%, τ 2 = 0.1160), confirmed by a highly significant heterogeneity test ( Q (7) = 34.0977, p < 0.0001), indicating that variability across studies exceeded what would be expected from sampling error alone.

Overall, zymosan treatment which was used for positive control resulted in a highly significant increase of both types of NETs, i.e., “cell free”- and “anchored”-NETs in bovine PMN ( p < 0.0001; Figures 3E–H ).

Global respiratory system compliance Comparing C rs (PEEP wave) to the reference values, we found a highly significant correlation with the reference value C rs (low-flow) ( r = 0.80; P <0.0001; C rs (PEEP wave) = 0.73 × C rs (low-flow) +21).

Indeed, there was a highly significant correlation between MMSE scores and educational level (r=0.601, p<0.0001; data nor shown).

The results shows that when analyzing all lung cancer patients versus healthy controls the diagnostic power of C1M, and VICM individually were highly significant with an AUROC of 0.97 and 0.85, respectively ( P < 0.0001).

Pooled left and right arm data were then compared between megachiropterans and microchiropterans and showed highly significant differences (T = - 8.77, P = 0.0001); and clear separation of measurements between the groups ( Fig 2C ).

However, there was a highly significant interaction between temperature and drought strategy ( F 1,124 = 41.77, P ≤ 0.0001), indicating that these groups of species responded to the experimental heat treatments differently.

Despite the variations between species within both groups, there is a large average difference between them and this difference between the groups is statistically highly significant ( P < 0.0001).

Conversely, Z1 degranulated MCs showed marked elevation in chronic periodontitis (4.69 ± 2.09) compared to healthy gingiva (1.63 ± 0.74), with highly significant intergroup differences (p = 0.0001).

The log-rank test revealed a highly significant difference in survival between the two groups (chi-square = 42.56, p < 0.0001).

The difference between self and others was highly significant (p<0.0001), but note the high variance induced in “other” condition using pinv.

Pairwise comparison between groups at each time revealed that all the test compounds induced a highly significant ( p < 0.0001) reduction in BGL comparable with the standard drug rosiglitazone.

Comparing the significant hypermethylated probes from CBCS cluster 3 with those from the `methyl deviator' signature, each identified from the 1505 CpG-probe GoldenGate background, we observed a highly significant correlation ( P <0.0001, Fisher's exact test), even though different algorithms were employed to derive each of these signatures.

There was a significant heterogeneity among studies I 2 = 88.7% (95% CI: 76.3–94.6%), τ 2 = 17.32, and a highly significant Q -test ( p < 0.0001) ( 14 , 17–20 ).

This was supported by statistical analysis that revealed that the frequency of polarization in HIV-1-infected T cells was highly significant compared to contacts formed between two uninfected T cells (odds ratio [OR] at 10 min, 1; OR at 20 min, 9; OR at 60 min, 17.9; Fisher's exact test, P < 0.0001) ( Fig. 1C ).

We found a highly significant interaction between the occurrence of native versus non-native amphipods and upstream distance ( Chi 2 value = 16.03, p value <0.0001; Fig. 1 ), reflecting that non-native species were mostly present at the outlet, while the native species were mostly present at the further upstream sites.

The results indicated that there was a highly significant association between PD-L2 and PD-L1 in these tumors ( p < 0.0001) [ 107 ].

Nevertheless, important differences in plasma cytokine levels were observed in HAT patients as compared to endemic, uninfected controls, with highly significant differences (p<0.0001) for IL1β, IL2, IL4, and IL10 and to a lesser extent for INFγ (p = 0.01).

For azimuthal error, the Mann–Whitney test revealed a highly significant effect (U = 205,723.5, p < 0.0001) with a large rank-biserial correlation (r a = −0.6425).

Results: At week-twelve, the respective values of area under the ROC curves of the studied biomarkers for pooled experimental cohorts were 0.928, 0.907, 0.908, 0.927, and 0.988 having the significance of accuracy (R-square):66.28%, 47.25%, 70.39%, 65.13%, and 68.00%, indicating a satisfactory treatment policy, their mean± SD, and risk ratio, all exhibited highly significant differences (p<0.0001) and KOA-gradation was upgraded between≥2 and ≥3 from≥4 as per the Kellgren-Lawrence scale compared to the control.