“highly significant”

The highly significant positive slope ( p < 0.0001) of relative amplitude squared on relative period further strengthens the prediction that coupling is present, as seen in the existing three families of clock models 34 , 35 .

A highly significant increase in anti-zEDIII IgG was verified in mice immunized with the IQB80 (10 μg) when compared with mice immunized with zEDIII without adjuvant ( p < 0.0001).

Of these, 3 were highly significant ( p < 0.0001) and were ultimately retained ( Table 3 ; Figure 2 ).

G2 also showed improvement, from 1.54 ± 0.61 at T0 (range 1–3) to 0.97 ± 0.62 at T1 (range 0–3), with a highly significant change (p < 0.0001).

Moreover, a highly significant difference in the number of resin tags was observed between the groups ( P < 0.0001).

The total SUPPS-P Impulsivity Score was lower in smokers (50.2) than in non-smokers (53.3), and the difference was highly significant (p<0.0001), suggesting overall greater impulsivity among non-smokers.

All correlations were highly significant ( P < .0001).

Despite age, sex, and procedural differences there was remarkable consistency in that in all 29 subjects, PAPP‐A levels in the conditioned medium of epicardial preadipocytes greatly exceeded those of subcutaneous preadipocytes, resulting in a highly significant 15‐fold difference by paired t ‐test ( P < 0.0001).

We observed that higher TSC correlated strongly with poorer outcomes and was highly significant with regard to disease progression when dichotomized at the median (median OS: 13 months vs 136, p < 0.0001 and median PFS: 5 months vs 85 months, p < 0.0001) ( Fig. 4 A and 4 B). p16-positive OPSCC have a proportionally smaller tumor stroma contact surface compared with p16-negative OPSCC We observed that the TSC was significantly higher in p16-negative OPSCC as compared to their p16-positive counterparts.

The results presented in Figure 1B–C clearly support our hypothesis: antibody treatment did not significantly impact tumor growth in B16.F10 challenged mice ( P = 0.1850); whereas the effect on B16.F10-GP challenged mice were highly significant ( P <0.0001).

However, there was a highly significant intra-subject correlation between pre- and post-treatment irisin concentrations (R = 0.82, P<0.0001).

The differences are highly significant ( P < 0.0001), except for class 2,2, probably because of its low incidence, as shown by χ 2 statistical analysis with Bonferroni correction.

This difference in the survival rate was highly significant in comparison to both the control Vehicle treated group (p<0.0001) and the PLX-Mat group (p<0.005).

Statistical analyses showed highly significant positive correlations (p<0.0001) between all of the units/titers measured in the different antibody assays ( Table 2 ).

Differences were highly significant in the chi-square test (P<0.0001).

We observed a highly significant correlation between both assays (r = 0.78, p<0.0001, Fig 2D ), indicating that HIV-Flow and mRNA Flow FISH provide similar estimates of the size of the translation competent reservoir in clinical samples.

Results The difference between ages of the two groups was highly significant ( P < 0.0001).

The effect of ever having been diagnosed with a mental health condition was highly significant as a main effect (p<0.0001) but did not differ significantly by ethnicity or age.

The chi-square analysis indicated a highly significant association between gender and cancer prevalence (χ 2 (1) = 27.535, p < 0.0001), with a higher prevalence observed among females (18.2%) compared to males (15%) in our sample.

These changes were highly significant at the first three stations ( P ≤0.0001) and marginally not significant at the latter station ( P = 0.08; probably because it did not include data for 2004–2010). 2.

Good overall model fit was confirmed by a Hosmer–Lemeshow statistic of 7.175 ( p > 0.05), and a highly significant likelihood ratio test (Wald χ 2 = 51.467, df = 7, p < 0.0001).

The mean numbers of SA and SU residues per molecule of FSH and LH in serum showed four different patterns during the cycle, all with highly significant ( P < 0.0001) differences between levels at different phases of the cycle.

Migration assays revealed that PRF caused a highly significant ( P < 0.0001) and higher than 15-fold increase (19.3-fold for DF, 18-fold for PDL, and 17.1-fold for AB) in the number of migrated cells when compared to DMEM medium, while platelet-poor plasma (PPP) only caused a moderate 5–10-fold increase in the number of migrated cells (7.8-fold for DF, 5-fold for PDL, and 7.1-fold for AB). 3.3.

At the end of 3 weeks; WOMAC score showed highly significant difference within ( P < 0.0001) and significant difference between groups ( P = 0.040) also by Time × group interaction ( P = 0.024), VAS showed highly significant difference within groups ( P < 0.0001).

A lower number of migrated cells can be observed in LIPUS-stimulated cells, and this difference was highly significant at 6 h ( p < 0.0001) (Fig. 4 C).