“highly significant”

There was also a highly significant (P<0.0001) difference in the IMA levels amongst the two types of malaria; falciparum (0.69 ± 0.05) and vivax (0.44 ± 0.06) ABSU ( Figure 2 ).

Importantly, a highly significant association was found between the G-allele and response to therapy in HCV genotype 1-infected patients (P<0.0001) but not in HCV genotype 3-infected patients.

1 e) and found a highly significant correlation (Spearman's r = 0.57 [95% confidence interval (CI): 0.54–0.60], p < 0.0001).

hsa-miR-93 displayed moderate up-regulation ( p= 0.064), while hsa-miR-106b, hsa-miR-221, and hsa-miR-222 exhibited highly significant overexpression ( p< 0.0001 for all).

The outcome of each statistical test was considered to be significant if p ≤ 0.05 and highly significant with p < 0.0001.

Quartile analyses confirmed minimal LPS effect in μG ( p = 0.1755), while differences between 1G and μG were highly significant ( p < 0.0001).

The relationship between APS2 and composite endpoint was highly significant (p < 0.0001), yet was not significantly different when stratified by age (p = 0.94) or sex (p = 0.337).

All regressions were highly significant (P-value < 0.0001), indicating that the relationships between Ct values and viral genome quantity were statistically robust.

Statistical analysis (ANOVA) showed highly significant effects between the groups ( P < 0.0001) on surface microhardness.

Results For all subjects analyzed, FEV 1 and FVC bronchodilator responses showed progressive and highly significant (p < 0.0001) declines over 4 years.

Similarly, Figure 4C,4D presents the analysis results of the entire TCGA dataset, showing highly significant differences in survival between the low- and high-risk groups (P<0.0001), consistent with previous results.

For the northern strain, the analyses showed a highly significant dependency of diapause on day length, when different constants were estimated for each T-cycle treatment (Fig. 2 a, b; n = 24, df = 18, dev. = 103.79, p < 0.0001).

Endpoint fluorescence quantification confirmed highly significant signals at concentrations of 10 6 to 10 3 copies/μL ( p < 0.0001) and statistically significant increases at 10 2 to 10 1 copies/μL compared with controls ( p < 0.01) (Fig. 5 G).

This observation was confirmed by the two-way PERMANOVA, which crossed swabbed region with health, stating that there were highly significant differences between regions and globally between health states (pseudo- F = 22.241, p -value = 0.0001, pseudo- F = 10.373, p -value = 0.0001, respectively) (Supplementary Table S1 ).

This regression was highly significant (standardized beta = 0.49 ± 0.002, t = 35.25, P < 0.0001, R 2 = 0.34; linear regression).

ANOVA demonstrated highly significant models for both responses (F = 130.35 and 92.02, respectively; p < 0.0001), with extraction solvent volume exerting the most pronounced influence on recovery (F = 315.12), followed by pH (F = 225.51) and disperser volume (F = 151.42) (Table 1 ).

In the presented patient cohorts the RFs reached highly significant predictions with an AUC of 0.8932±0.0052 ( p <0.0001 for NAFLD vs.

In all cases, the slope of the regression was highly significant ( p < 0.0001), and the R 2 was between 0.36 and 0.39.

PELNs intervention resulted in a statistically significant change in the Chao index ( p = 0.05) and a highly significant change in the Shannon index ( p < 0.0001).

In a model including both eyes, the effect of relative clause type does not reach significance ( β = 0.071, z = 1.46, p = 0.14), but we again find a highly significant interaction of RC type and item order ( β = −0.062, z = −4.07, p < 0.0001).

The values obtained are highly significant (P < 0.0001).

The TPC model was highly significant ( p < 0.0001), confirming that the selected factors substantially influence extraction yield.

Overall, the immunoglobulins evaluated increase after the first immunization and were maintained over time, showing highly significant differences when compared with the controls PBS+CFA and PBS+alum ( p < 0.0001).

A direct statistical comparison of genotype–phenotype profiles ( Supplementary Table S1 ) confirmed several highly significant associations. mecA -positive isolates exhibited a 16-fold increase in oxacillin MIC (median 4.00 vs. 0.25 μg/mL, p < 0.0001) and a 5.6-fold increase in penicillin MIC.

Multivariate modelling of global health status (EORTC QLQ C30) at 2 years indicated baseline quality of life as a highly significant factor (p < 0.0001).