“highly significant”

For the bivariate associations (controlling for clustering within state) all the associations (tested using design based F-statistic) were highly significant (P < 0.0001) except ownership (public versus private) and region.

A one-way ANOVA test conducted across all transformer-based models yielded a highly significant result (F = 163, p < 0.0001), clearly indicating that model performance in terms of accuracy was not uniform.

The most substantial impact on elastase inhibition, as indicated by the IC 50 value, was attributed to temperature (B), which exhibited a regression coefficient of 12.87 and a highly significant p -value ( p < 0.0001).

Pairwise comparisons showed highly significant differences (p<0.0001) between protected and unprotected lands, as well as between partially protected and unprotected lands.

Highly significant ( P < 0.0001) differences in susceptibilities to the disease were detected among the evaluated germplasm.

total and stage I+II ovarian cancer is highly significant (P<0.0001) but negligible for healthy vs. stages III+IV cancer (P = 0.043); in contrast for the more important differentiation between benign vs. ovarian cancer, the difference between CA125 and the panel is missing for benign vs. total and stage I+II ovarian cancer and rather better for benign vs. stage III+IV ovarian cancer (P = 0.045).

Group 2 showed highly significant difference in leakage values in comparison to group 1 ( P value<.0001).

Correlations of the HR with ambient temperature and heat index were also negative and very highly significant ( P < 0.0001) in both sexes of the AGRs.

The significant effect of irrigation on stem length was observed only at later growth stages, with significance emerging at 3 MAT ( p<0.01 ) and becoming highly significant at 4 MAT (p<0.0001) .

Thus, as on Day 0, there was a highly significant (p < .0001) effect of time of day on each day (1–11) with elevated levels occurring at the same ZT times as on pre-shift Day 0.

Transfer of CD4 + CD25 + T cells resulted in a highly significant amelioration of EAE signs (ANOVA: P < 0.0001).

There were highly significant ( p < 0.0001) associations between the abnormal expression of E-cadherin and Vimentin, E-cadherin and β-catenin, Vimentin and β-catenin, SMAD4 and E-cadherin, and a significant association between SMAD4 and Vimentin ( p = 0.0003), and SMAD4 and β-catenin ( p = 0.001) as shown in Table 1 .

Generally, a p -value less than 0.05 indicates that the corresponding factor is significant. Therefore, the quadratic polynomial model established in this experiment is highly significant ( p < 0.0001). 55 The model’s R 2 is 0.9757, and the adjusted R 2 is 0.9514, indicating a good fit with minimal experimental error.

After statistical analysis, the F -value of the APS of the lignin nanoparticles model is 230.57, all of which are highly significant ( p -value < 0.0001), and the p -value of the lack-of-fit term is not significant ( p > 0.05), suggesting that the model is accurate and reliable.

Whereas centrosomal pT676 staining in cells expressing GFP alone was essentially the same as in untransfected cells (the median value of F pT676 (GFP+)/ F pT676 (GFP–) was close to 1), there was a twofold reduction in centrosomal pT676 in cells expressing GFP-Cetn3 ( Figure 10B ), and the difference between GFP and GFP-Cetn3 was highly significant ( p < 0.0001).

This difference was highly significant (p-value < 0.0001).

Establishment of Regression Equation Model and Significance Test Response-surface analysis ( Tables S2 and S3 ) yielded a highly significant model ( p < 0.0001) with non-significant lack of fit ( p = 0.1273), indicating that only random error contributed to residuals.

Among both British and Scandinavian populations, LD-based estimates of effective population size were similar to census population sizes and showed a highly significant relationship ( F 1,33 = 37.12, p < 0.0001; Fig. 3 ; data are presented in Supplementary Table S8 ).

In Group 4 one patient died from peritonitis while in CR, one from complications of paraplegia while in relapse, one from multiple system failure with minimal hepatic HD and one patient who died at home while in relapse. Excluding the patients above re-analysis of survival still showed a highly significant trend (P<0.0001) for atopic strata.

Both nuisance factors were highly significant (sample size: X 2 = 58.407, df = 1, p < 0.0001; mean quality of fixes: X 2 = 11.268, df = 1, p = 0.0008), indicating that these factors play an important role in determining home range size using 95% KDE and that it is justified to account for them in our models.

Similarly, the p -values remained highly significant ( p < 0.0001 for uncorrected and corrected), further confirming the strong correlation between temperature and uptake rate constants in both cases.

The AR(1) (−0.690582) and MA(2) (−2.00298) coefficients were also highly significant ( p < 0.0001), confirming the autoregressive structure of the model.

A negative, highly significant correlation was found between AQP1 abundance and the D/P Crea ( r = −0.76, p < 0.0001). 4.

There was no statistical significant difference in the evolution of the HHS between the three groups (Table 2 ). Viscosupplementation provided a highly significant pain reduction in the Adant-group ( P < 0.0001), a significant pain reduction in the Synocrom-group ( P < 0.05) and a pain reduction that did not reach significance in the Synvisc-group ( P > 0.05).

GAS6/AXL pathway-related parameters GAS6 and AXL levels showed a highly significant decrease in the DN group than in the DM group, which, in turn, showed a significant decrease than in the controls at p < 0.0001.