“highly significant”

The differences in miRNA expressions between AMD patients with and without congenital hemochromatosis and the controls were highly significant (expression was not observed in controls) (p<0.0001).

The ANOVA indicated highly significant differences between the Chatino, Chontal, and Chinanteco groups regarding the number of mushrooms they know and use ( F = 10.9, p < 0.0001).

For both genotypes, delta power in both baseline and recovery from SD could be reliably predicted on the basis of sleep-wake history (Figure 1 ), which is underscored by the highly significant correlations between empirical and simulated data (r = 0.91 and 0.87 for cry1,2 +/+ and cry1,2 -/- , respectively, P < 0.0001 for both genotypes).

They found a small, but highly significant, decline in the strength of reported correlations with publication date (best model: P < .0001; R = -0.133) and with sample size (best model: P < 0.002; R = -0.188).

Indeed, permanent expression of LMP1 in the BJAB-tTA-LMP1 cell line induces significant down-regulation of telomere repeat binding factor 1 (TRF1), TRF2 and protection of telomere 1 (POT1) at both the transcriptional and translational level (the most impressive down-regulation (>60%) was observed in TRF2), resulting in a highly significant increase of multinucleated, LMP1+ RS-like cells ( p < 0.0001) on days 14 and 21 [ 67 ].

As expected, the main effect of Load was highly significant, reflecting progressive APS decreases with increasing loads ( F (2,76) = 21.46, P = 0.0001).

Substance and alcohol abuse and supplement use Association with MD and alcohol use measured by RAPI was highly significant (Table 5 ) (p < 0.0001).

After 1 year of follow‐up, the overall prevalence of symptoms decreased to 49% among women and 33% among men, but the sex‐specific difference remained highly significant ( P <0.0001).

Differences between concentrations were highly significant (P < 0.0001; F 6,45 = 26.92).

It is of note, however, that our results still demonstrate high mortality when the TLR3 −/− strain was infected by a high viral amount of IAV, although the difference between this group and wild-type animals is highly significant ( p < 0.0001).

No protective habits were associated with the frequency of the outcome.- Among the different types of work, one is highly significant-forest work (RR= 1.43, 95% CI 1.22-1.69, p< 10-4).

The distribution of the correlation values was skewed towards positive values with a median of 0.17 and a most probable value of 0.4, results that show a highly significant deviation from randomness (Wilcoxon test, p < 0.0001).

Statistical analysis confirmed that the reduction in viability at concentrations ≥ 2.50% was highly significant (**** p < 0.0001).

While these effects were highly significant (overall p < 0.0001), the differences in intake were small and not clinically meaningful.

As shown in Table 1 , one-way ANOVA indicated a highly significant main effect of the immunization regimen on antibody titers ( F (3, 36) = 24.68, p < 0.0001).

Two-way ANOVA revealed highly significant main effects of both cell type (F 1,14 = 89.42, p < 0.0001) and ZnO concentration (F 3,14 = 11.00, p < 0.001), with no significant interaction effect (F 3,14 = 1.25, p = 0.326), indicating that the differential sensitivity pattern remains consistent across all tested concentrations.

ANOVA ( Table 4 ) revealed that the model was highly significant ( p < 0.0001).

[ 6 , 7 , 15 ] conducted a series of studies that revealed the prognosis for high-grade osteosarcoma of the extremities metastatic to the lung, with a 5-year EFS rate of 36% for patients with localized disease who later relapsed and 9% for patients with resectable lung metastases at presentation; the difference was highly significant ( P < 0.0001).

We found a highly significant correlation between the extent of intermingling and translocation frequency ( p < 0.0001; Figure 2 B), such that higher levels of CT intermingling increase the chances of double-strand breaks (DSBs) being involved in rearrangements with other chromosomes.

Body conformation indices of pelvic index, body index, transversal pelvic index and weight were highly significant ( p < 0.0001) among the studied districts.

This difference was highly significant (p < 0.0001).

The differences in gene-expression ratios corresponding to 1-, 1.5- and 3-fold dose changes on chromosome 2L are highly significant ( p << 10 -4 by ANOVA followed by Tukey HSD, Hodges-Lehmann, and Kolmogorov-Smirnov tests; see Materials and methods).

On average, only 4.9 ± 0.7% of proliferating normal epithelial cells in TDLUs simultaneously expressed ER-α, compared with 27.6 ± 2.2% in HELUs, which was also a highly significant difference ( P < 0.0001).

Using the same statistical procedure described for Figure 2 , this overlap between the experimental data and the theoretical prediction is highly significant ( P < 0.0001).

qPCR validation of a set of selected targets showed a highly significant correlation with the relative expression levels determined by RNA sequencing (Pearson R = 0.8955; P < 0.0001; Supplementary Figure S9 A).