“highly significant”

This difference remained highly significant after formal statistical comparison (Mann–Whitney U test, p < 0.0001) ( Figure 7 ).

A highly significant association between the presence of p53 gene mutation and nuclear accumulation of p53 protein was found ( P < 0,0001).

A one-way ANOVA revealed a highly significant difference in Ki-67 expression among the four treatment groups (F = 41.40, p < 0.0001), with a large effect size (R 2 = 0.8923), indicating that approximately 89.2% of the total variance in Ki-67 expression was attributable to treatment effects.

The deviations between the torsional spaces covered are highly significant for almost all maps (p-value < 0.0001), with significantly higher mean distance-to-centroid for all MD maps (see also Additional file 1 : Table S4).

Wilcoxon signed rank testing revealed no significant difference between the A1 and O1 groups (P = 0.1810) but a highly significant difference between the A2 and O2 groups (P < 0.0001).

The evaluation of the diagnosis showed A highly significant tendency (P < 0.0001 *) to: Gartland I Conservative conduct 87.2% and surgical Conduct-Gartland III 74.2% ( Table 2 ).

Again, seasonality had a highly significant effect on both metrics ( P < 0.0001), while the health status was non-significant ( Table 1 ).

The statistical analysis showed that the determined values of the contact angle and roughness for all the samples are highly significant ( p < 0.0001).

Statistical analysis revealed highly significant differences between the control and diabetic groups ( p = 0.0001) and between the control and diabetic nephropathy groups ( p < 0.0001).

Strikingly, the activity in lymphoblasts showed a highly significant positive correlation with levels of DHRSX protein in this cell line (see Figure 1 J) (NADH: R 2 = 0.9667; p < 0.0001, NADPH: R 2 = 0.9910; p < 0.0001; Figure 3 E).

Treatment was highly significant for TMAO concentrations ( P < 0.0001) and yields ( P < 0.0001), where colostrum from both CHOL45 and CHOL30 cows had greater concentrations (both comparisons, P < 0.0001) and yields (both comparisons, P < 0.01) than CON.

The Kruskal–Wallis test indicated a highly significant difference in plasma PlGF concentrations (P < 0.0001; Figure 2 ) between groups.

The stage factor remained highly significant in all cases [F(2,54) = 70.63; p < 0.0001], reflecting the expected general progression of seizures.

ANOVA showed a highly significant effect of genotype (F 1,54 = 206.8, p<0.0001), but no significant effects of treatment (F 1,54 = 0.07, p=0.80) or genotype x treatment interaction (F 1,54 = 0.31, p=0.58).

In general I-PTH and Bio-PTH showed highly significant correlation (r = 0.952, p < 0.0001).

Between-treatment differences remained highly significant at the 24-hour time point regardless of baseline WHO/ECOG performance status (performance status ≤2: 0.87 vs 17.79 hours; P < 0.0001; performance status >2: 1.46 vs >24 hours; P < 0.0001) ( Figure 2 B).

Whereas the original data analysis reported a highly significant effect ( P < 0.0001), generalized mixed-effects models with a random effect for name indicates that the effect is not robust, neither with the data from the general public (b = −0.108 [log odd units], z = −1.712, P = 0.087) nor with the data from elected officials (b = −0.065, z = −1.432, P = 0.155). * While this does not mean that we should accept the null hypothesis, it shows that the study is underpowered.

A highly significant difference (p < 0001, by unpaired t -test) was observed between ThT fluorescence before and after fibril formation, and this difference was greater than 4 fold for both fibril types tested.

A highly significant correlation was found between NIHSS and FIM ( p < 0.0001), confirming that NIHSS scores are a good predictor of stroke disability in terms of FIM and functional gain. 50 One study also found that there was a significant association between NIHSS and upper extremity impairment and stroke severity. 51 This may explain why there was a significant correlation between NIHSS and ARAT scores for assessing arm function in stroke patients in the present study.

Pearson’s correlation analysis ( n = 45) showed a powerful and highly significant positive correlation between daily As intake and the hazard index (r = 0.97, p < 0.0001), indicating that arsenic is the primary contributor to HI from the consumption of these dietary supplements.

In particular, the variable methanol % exhibited a highly significant ( p < 0.0001) influence on TPC yield.

10.1136/bmjgh-2019-001837.supp2 Supplementary data Correlations of anaemia between children and women Despite the fact that the prevalence of anaemia in women was much lower than in children, the prevalence of total anaemia, moderate+severe anaemia and mean haemoglobin concentration between children and women showed a highly significant, strong positive correlation (0.80, 0.76, 0.79, respectively; p<0.0001 for all).

The difference between total mortality of treated and control groups was highly significant (P= 0.0001) ( Jalilnavaz et al. 2016 ).

A highly significant decrease ( P value = 0.0001) in the expressions of miRNA-106a and miRNA-20a was reported in COVID-19 patients compared to controls.

One-way ANOVA revealed a highly significant overall difference among groups (F(8,81) = 177.509; P < 0.0001; Tukey HSD = 8.786 MPa).