“highly significant”

The test for residual heterogeneity (QE) remained highly significant (QE = 125.38, df = 29, p < 0.0001), confirming that substantial heterogeneity persisted even after adjusting for the included covariates.

This difference was highly significant, t(70.14) = 4.04, p = .0001 (degrees of freedom using Satterthwaite’s correction for unequal variance).

After adjusting for a range of other prognostic factors through recursive partitioning analysis, baseline nutrition support remained as a highly significant ( P <0.0001) risk factor for locoregional failure and death.

The blood glucose level estimation on the third day after streptozotocin (STZ) administration for the confirmation of induction of diabetes in the experimental animal groups revealed a highly significant (p<0.0001) increase in the blood glucose level (21.26 to 22.81 mmol/L) of all experimental groups except nondiabetic control ((6.53±0.2) mmol/L) and vehicle control ((6.66±0.15) mmol/L) groups.

We observed a highly significant difference (p value = 0.0001) between patients’ antibody response to P3/FUR/x3 based on their disease status.

A dispersed clustering was observed for both K . maduraiensis and K . varshneyi . The CDA showed a highly significant Wilks’ λ value (1.0 × 10 − 8 ), Pillai’s trace, Hotelling–Lawley Trace, and Roy’s greatest root ( P < 0.0001) ( Table 8 ).

Treatment-related differences were found to be highly significant ( P < .0001) in favor of Enterokind.

Despite this observed variability between immune responses at 7 days p.i., the difference in proliferative responses to viral and myelin antigens in infected and control groups was highly significant ( p <0.0001).

There was a highly significant interaction with age (p < 0.0001), such that the association was only observed for younger compared with older individuals: HR 1.27 (1.15-1.39) and HR 1.00 (0.92-1.09) in individuals ≤75 years and >75 years, respectively.

The comparison between SEA and MEA DEGs revealed 248 downregulated and 29 upregulated genes that are shared in both diseases, showing a highly significant concordance (Fisher’s exact test, p < 0.0001; Figure 3 ).

General combining ability (GCA) and specific combining ability (SCA) effects were highly significant ( P < 0.0001) for all traits.

In contrast, spheroids in the NAFLD group featured highly significant increases in expression of G6PC (6.2‐fold; P < .0001), PCK1 (6.1‐fold; P < .0001), and FASN (13.3‐fold; P < .0001).

In each of the three analyses, there was a negative, highly significant correlation between salmon stock development and watermill development (Period 1260–1940: declining stocks for periods without data: r = −0.813 and P < 0.0001; Period 1260–1940: constant stocks for periods without data: r = −0.828 and P < 0.0001; Period 1550–1940: declining stocks for periods without data: r = −0.903 and P < 0.0001).

CFR among partially vaccinated is four times more than the CFR in unvaccinated, and the difference is statistically highly significant (p = 0.0001) ( Table 1 ).

The differences in peak responses induced by a single C, M and P administration were highly significant ( P < 0.0001) (Kruskal-Wallis test), as was C vs P ( P < 0.0001) (Dunn’s multiple comparison test).

Consumption of 15 g alcohol or more per day was associated with a relative risk of 1.6 (95% CI, 1.3 to 2.0) and there was evidence of a highly significant increase in risk with increasing reported alcohol consumption (Mantel extension χ for linear trend = 4.2, P <0.0001).

However, Group B demonstrated greater improvement than Group A, with highly significant results (p<0.0001).

The 300 values of the RMS standard deviations (SD) associated with the three channels of the calibrated and non-calibrated orthophoto were compared by means of a paired Wilcoxon test for non-parametric distributions which reported a highly significant difference ( p < 0.0001) between the calibrated and non-calibrated images ( Table 3 ).

Results Analysis of the interventions indicated a highly significant ( P < 0.0001) mean reduction in attendances.

Statistical evaluation indicated that the difference in the staining intensity of the different populations of CD-immunoreactive cells was highly significant (one-way ANOVA, for CD34, F (18.306) = 389.861; P<0.0001 and for CD38, F (2.633) = 2573.162; P<0.0001).

Notably, responses to Question 3, which assessed processed food intake frequency, revealed a highly significant difference between the breast cancer and reproductive system cancer groups (χ 2 = 38.30, p < 0.0001), indicating a marked disparity in reported behaviors between these two populations.

The correlation of health practices related to vitamin D status with dental caries was highly significant ( p = 0.0001), and lesser exposure to sun was also significant ( p = 0.002) ( Table 2 ).

The relative proportion of C>T/G>A changes was highly significant compared to other nucleotide changes (p < 0.0001, Kruskal–Wallis one-way analysis of variance) and formed 32% of all nucleotide changes overall, a proportion that was double what was expected due to chance.

Dyspnea Two prospective intervention studies 28 , 29 evaluated dyspnea, showing highly significant results between before and after the exercise intervention (P < 0.0001 and P = 0.022, respectively).

In contrast, the relationship between the human and sloth SPDs is positive and highly significant ( r s = 0.35, P < 0.0001), suggesting those populations fluctuated together from extrinsic factors.