“highly significant”

Treatment was highly significant for TMAO concentrations ( P < 0.0001) and yields ( P < 0.0001), where colostrum from both CHOL45 and CHOL30 cows had greater concentrations (both comparisons, P < 0.0001) and yields (both comparisons, P < 0.01) than CON.

ANOVA results ( Supplementary material 1 , Table S5 ) indicated that the model was highly significant (P < 0.0001), while the lack-of-fit was not significant (P = 0.102 > 0.05), supporting good model adequacy within the studied region.

Actual renal clearance during subnormothermic machine perfusion, however, yielded a much closer and highly significant correlation ( r 2 = 0·82; P = 0·0001) with ulterior kidney function upon reperfusion.

Single‐sample analysis The paired t ‐test analysis revealed highly significant differences ( p < 0.0001) when comparing scores before and after the prosection activity.

The effect of adapting speed was highly significant in ANOVA (F(2,8) = 142.57; p < 0.0001; effect size η 2 p = 0.97).

Linear regression analysis revealed a highly significant positive correlation ( r = 0.2426, P < 0.0001).

The linear regressions between the available energy and the measured energy fluxes were all highly significant ( P < 0.0001).

This demonstrated that the lipolysis/plasma lipid relationships were still highly significant ( P <0.0001) after correction for sex; age; body mass index; waist circumference; waist-to-hip ratio; nicotine use; treatment of type 2 diabetes mellitus, hypertension, or hyperlipidemia; and fat cell size.

Robustness Analysis FDR-adjusted analyses confirmed the stability of the main findings: several group-level effects remained highly significant after correction—most prominently the AI of lobules V, VI, VIIIB, and IX (e.g., Lobule IX Volume Asymmetry: F(1,95)=17.53, P < .0001, q = 0.0012, partial η 2 = 0.156) and the left-sided thickness and volume of Lobule IX (F(1,95) = 10.28, P = .0018, q = 0.0198, partial η 2 = 0.098).

A paired t -test across languages showed that, in both cases, the difference was highly significant in the predicted direction ( p < 10 −4 ).

When conservation of N- acetylated CysLys pairs relative to non-acetylated CysLys pairs was plotted against the maximum lifespan of 52 mammal and bird species, there was a highly significant negative correlation (p < 0.0001) and no significant correlation for N- acetylated cytosolic SerLys pairs (p = 0.32; Figure S3 A).

6 e) that the PDA@Pt-LFIA catalytic mode showed a highly significant negative correlation with qPCR results ( r = -0.968, P < 0.0001), indicating that LFIA in the catalytic mode has clinical quantitative diagnostic potential equivalent to that of qPCR.

Highly significant differences ( p < 0.0001) were found among thermal oxidation times across the 0.5–2.5 THz range.

As shown in Fig 1A and 1B , a highly significant effect (p < 0.0001) was found in different PL concentration ranges tested in MM-231 and MM-468 cells.

A first study including 229 PCOS patients and 150 controls reported a highly significant association of Gln223Arg SNP in the LEPR gene with the development of PCOS ( p < 0.0001) [ 129 ].

These observations were supported by highly significant effects of Period (F (1,17) = 89.00 P < 0.0001), Session (F (7,119) = 28.51, P < 0.0001) and of the Session X Period interaction (F (7,119) = 11.69, P < 0.0001).

65,66 Statistical analysis confirmed these reductions were highly significant ( p < 0.0001) compared with the EAC control.

The size differences between the colonoids treated with tofacitinib and budesonide were highly significant ( P = 0.0001) for all donors at both 2 and 20% oxygen (Fig. 3 a-b).

Significance levels were categorized as follows: p > 0.05 (ns) for non-significant, p ≤ 0.05 (*) for statistical significance, p ≤ 0.01 (**) for very significant, p ≤ 0.001 (***) for highly significant, and p ≤ 0.0001 (****) for extremely significant, respectively.

All vaccinated groups showed 0% mortality when challenged, which was highly significant compared to the non-vaccinated controls (40 and 28% mortality eight and twenty-six weeks post vaccination (wpv), respectively) (P<0.0001).

Only regions that showed a highly significant univariate heritability ( h 2 SNP p <0.0001) for both schizophrenia and the cardiac trait were tested for local genetic correlation.

LVEF ≤ 0.45 was the single independent and highly significant predictor of early CHF among other clinical and echocardiographic variables (odds ratio 17.0; [95% CI 4.1 - 70.8]; p < 0.0001).

We found a highly significant lower frequency of SARS-CoV-2-specific TNF+CD4+ and CD8+ T cells ( p < 0.0001) correlated with increasing BMI category (Supplementary Table 11 ; ANOVA for general linear models with adjustment for covariates), as well as trends of lower SARS-CoV-2-specific IL-2+CD4+T cells and higher CRP ( p ≤ 0.014, q < 0.156).

While there was no difference in baseline compliance among the two groups (14.58% compared to 12.43%), there was a significant difference when measured at follow-up (32.03% compared to 23.05%) and the magnitude of improvement (17.45% versus 10.62%) was also highly significant ( P <0.0001).

3c ), highly significant effects in paired two-way t tests (weakest effect: p = 0.0001), indicating that our experimental conditions do give rise to the so-called stereo-movement suppression phenomenon.