“highly significant”

Two-way ANOVA showed highly significant effects of treatment, cell death state, and their interaction (F (15,48) = 1810.36, p < 0.0001), confirming that treatment-dependent differences varied strongly across states.

Baseline CSF apoB levels showed highly significant associations with t‐tau and P‐tau ( R 2 = 0.23 and 0.28, both P < .0001, Figure 2 ).

There were strong and highly significant associations (p < 0.0001) between Fe NO and sputum eosinophils, regardless of whether the data was expressed as percentage differential or cell count.

Tiger caregivers in private facilities all had direct contact with the young tigers provided for the tourists, whereas none of the caregivers in government facilities had direct contact with tigers: a highly significant difference despite the small number of tiger caregivers ( p < 0.0001).

By one-way ANOVA, the main effect of genotype on all four genes was highly significant (p<0.0001), and for each gene, at least four of the six pairwise genotype comparisons showed significant differences in expression ( Supplementary file 3 ).

We found a highly significant relationship to IgM RF ( r = 0.45, P < 0.0001) (Figure 1 B), with a much weaker relationship to IgG ACPA ( r = 0.17, P = 0.03) (Figure 1 D).

When patient antibodies were correlated to the JADI-A scores, we found a highly significant association to the number of antibodies detected (p = 0.0001).

This improvement was highly significant ( p < 0.0001) in terms of the paired comparison of AUC between the two versions of the tool.

Three marker haplotype analyses revealed highly significant differences between CD patients and control subjects ( χ 2 = 29.9, df = 7, P = .0001) and UC cases and controls ( χ 2 = 46.3, df = 7, P < .0001).

This doubling of prevalence was highly significant with a difference of 3.7% ( z = 4.10, p < 0.0001).

An analysis of variance of the factor score variances was statistically highly significant ( P < 0.0001) indicating that a large amount of the periodic variability could be explained by the variances in the physiochemical attribute factor scores.

At 30 days post-injury, B cell-treated animals showed highly significant improvement in Y maze performance (p < 0.0001), with better alternation scores as compared to saline-treated ICH controls and values similar to sham-injured controls ( Fig. 2 E).

Target density, cull capacity, and cull radius were highly significant main effects by county, culled animals, culled farms, and epidemic length according to Type I and Type III analyses of likelihood ratios ( χ 2 , P < 0.0001).

The mortality was not significantly different between patients with and without complications ( P = 0.52), while there was a highly significant difference in LOS between subjects with and without complications (median, 6 versus 18 days, respectively, P < 0.0001).

In all three studies, the primary endpoint was achieved, with a highly significant reduction in PANSS total score from baseline to endpoint (p < 0.0001).

Body mass index reductions after LSG were highly significant compared to baseline values at all time points over 10 years ( p = 0.0001) and remained significantly lower for up to 7 years post-KT.

Also, the random effects were not centered on 0, with highly significant deviations ( p < 0.0001) for the apparent central volume of distribution (V2/F), the apparent peripheral volume of distribution (V3/F), and T lag ; and the largest deviation corresponding to a 43% higher V2/F.

We found a direct and highly significant correlation (gRVLP: R 2 = 0.794, p < 0.0001; LVLP: R 2 = 0.857, p < 0.0001; egRVLP: R 2 = 0.830, p < 0.0001) between GE efficiencies and Cas9 amounts for each of the three VLP types.

However, when all plasma melatonin concentrations ( n = 141) on Day 3 were correlated with GA, the Spearman correlation coefficient of 0.53 was found to be highly significant ( p < 0.0001, Figure 2 ).

There was no significant effect of insect group on feeding duration (ANOVA: F 2 , 225 = 0.077; P = 0.926), whereas waveform type had a highly significant effect ( F 5 , 225 = 1,598.35; P < 0.0001), confirming that time allocation differed strongly among feeding activities but not among insect groups.

Cadmium The Kruskal–Wallis test revealed highly significant differences (Kruskal–Wallis χ 2 = 27.00, p < 0.0001) between medians.

As shown in Supplementary Table S3 , A (Time) were significant ( p = 0.0018); B (Temperature) and C (Kinds of acid) was highly significant ( p < 0.0001).

All patients provided informed consent (IRB University of Freiburg #514/18) to the study (DRKS-ID: DRKS00020522) We found a highly significant correlation of both on-site and shipped DBS samples with serum samples (n=100, Figure 1A and B; p < 0.0001) as well as within non-shipped and shipped DBS samples (n=100, Figure 1C; p < 0.0001).

This approach allowed for the identification of the individual and interactive influence of each variable on the response, providing a predictive model to optimize the formulation, as shown: ST red = 31.291 + 0.134A − 0.519B + 0.154C + 3.409D − 1.149AB + 0.595AC + 1.810AD − 1.433BC − 1.981BD + 0.766CD − 0.316A 2 + 0.065B 2 + 0.102C 2 − 0.597D 2 , (7) The analysis of variance (ANOVA) for the quadratic model of surface tension reduction (ST red ) is presented in Table 3 and revealed that the model was highly significant, with an F-value of 14.78 and p < 0.0001, indicating a strong fit to the experimental data.

Our measurements showed that MCF-10A had a small, yet highly significant, preference to grow on 2D conditions compared to control 3D ECMs (1.1 fold, with P < 0.0001) or tumor-associated 3D ECMs (1.3 fold, P < 0.0001).