“highly significant”

Taken together, the BoAstV CH13/NeuroS1 infection that we detected by ISH and IHC in approximately 1/3 of cattle diagnosed with non-suppurative encephalitis, while negative controls remained unstained, clearly shows a correlation with the disease, which is supported by an extremely highly significant statistical correlation (two-tailed p < 0.0001). 3.2.

3.2 Menopause rating scale and menopause-specific quality of life questionnaire The individual change for the domains (psychological and urogenital) in week 4 was also highly significant ( p < 0.0001).

agulhensis had a negative and highly significant Fu's F S test (−22.82, P<0.0001); C. sinicus was also negative and significant (−7.29, P = 0.008).

For qPCR validation, we selected genes representing different functional categories within the WGCNA red module: (1) TIMP1—the hub gene identified by machine learning; (2) HCLS1 and C5AR1—two of the five candidate genes with known immune regulatory functions; (3) THBS4 (Thrombospondin 4)—although not among the final five candidate genes, THBS4 was a highly significant DEG (log2FC = 8.36, p < 0.0001) within the red module with established roles in extracellular matrix remodeling and cardiac fibrosis ( 28 ).

For the constructs with from 2 to 7 rrn operons, the relationship between the lag and the number of rrn operons is roughly linear, with a highly significant slope ( P < 0.00010), for 188 degrees of freedom: P (−17.0 < ρ < −13.6) = 0.95.

This represents a highly significant overlap (odds ratio (OR) = 10.45, p < 0.0001, and OR = 18.74, p < 0.0001, respectively; Figure 2 ) which could explain some of the synergistic/additive effects of LMP1 and LMP2A observed in mouse B cells described above.

Results The statistical association between predicted TKV at the time of a 30% decline of eGFR and that at the time of end-stage renal disease were both highly significant ( P < 0.0001).

However, we noted a 20-fold increase in the frequency of H2AX −/− bouquet-stage nuclei ( H2AX −/− , 6%; wild-type, 0.4%; based on 2,567 mutant and 2,772 wild-type spermatogenic nuclei), with the differences being highly significant (P < 0.0001; χ 2 and Fisher test; Fig. 2 B).

The results from GLMMs model showed a highly significant relationship ( p < 0.0001) of both water temperature and light attenuation coefficient to Chl a concentration ( Figure 5 ).

One-factor ANOVA revealed a highly significant effect of orientation, F (3, 51) = 85.06; p < .0001.

* indicates p‐value 0.01 to 0.05 (significant) ** indicates p‐value 0.001 to 0.01 (very significant) *** indicates p < 0.001 (highly significant) **** indicates p < 0.0001 (extremely significant) 4.14.

On meta-regression analysis, the combined impact of all covariates in the model explained at least some of the variance in effect size (Q = 16.21, df = 6, P= 0.0127), and the proportion of variance explained by covariates on comparing the model with and without the covariates was 73 % and highly significant (Tau2 = 0.1100, Tau = 0.3317, I2 = 86.5%, Q = .99, df = 10, P<0.0001) (R2 = 0.73).

Urea, creatinine, MDA and TNF-α levels increased markedly after TAA treatment and showed highly significant difference when compared to the control ( P <0.0001 for all).

A highly significant correlation (r = 0.74, p < 0.0001) between the LAST and the short version of the Token Test indicated good external validity of the scale.

By contrast, in NT animals, the success rate following the US stimulation of their visual cortex dropped to 38.1 ± 18.5% (s.d.), and the difference with the success rate following LS on the fourth day was highly significant ( p < 0.0001) (Fig. 6d and Extended Data Fig. 6 ).

alocis exhibited a highly significant association with HbA1c (r = 0.80; p < 0.0001), reinforcing its dependence on metabolic dysregulation, whereas P. gingivalis demonstrated moderate positive correlations with both PPD (r = 0.38; p = 0.04) and CAL (r = 0.38; p = 0.04), reflecting its role in progressive tissue destruction, alongside a persistent correlation with HbA1c (r = 0.57; p = 0.001).

Between-treatment differences remained highly significant at the 24-hour time point regardless of baseline WHO/ECOG performance status (performance status ≤2: 0.87 vs 17.79 hours; P < 0.0001; performance status >2: 1.46 vs >24 hours; P < 0.0001) ( Figure 2 B).

Highly significant (p < 0.0001) and close (Spearman r = -0.91) correlation between binding affinities determined by SPR and the mol% binding determined in the pull-down assays was observed for the interactions of both wild-type (closed symbols) and ΔH C loop-mutant (open symbols) H C B (triangles), H C DC (squares), and H C G (circles).

The model was highly significant ( F = 11.979, df = 2102; p < 0.0001) and is shown in Table 2 .

The two approaches showed very strong agreement, with a highly significant correlation ( p < 0.0001, r = 0.99).

There was a highly significant progression towards more complexity, with lower Bloom's scores in Cycle 1 relative to Cycle 2 (mean difference = 0.42, Wilcoxon rank sum test W = 2044567, P < .0001), and lower in Cycle 2 compared to Cycle 3 (mean difference = 0.84, W = 120920, P < .0001).

The data indicate that the regression model is highly significant ( p < 0.0001), with a non-significant lack-of-fit term ( P = 0.9490 > 0.05), demonstrating a good fit and low experimental error.

We obtained highly significant differences ( P < 0.0001), indicating a clear batch effect.

Copulsatility of the GH and GHRH hormone series was highly significant in both patients ( P < 0.0001).

MSR gene sets increased most at weeks 1 and 2 in all strains but the CAST/EiJ, and this difference between strains was highly significant (adjusted P < 0.0001).