“highly significant”

Conclusion From the above concrete observations, it can be hypothesized that AHCC is promoting proliferation and differentiation of leukocytes (multipotent stem cells), as it is seen that the genes responsible for these such as LAT, FLRT2, GIT-1, and so forth, as seen in Figure 5 , are upregulated and highly significant ( P < 0.0005).

The exponential model on a log e H vs Y scale also demonstrated a highly significant linear relationship (F 1,5 = 137.08, P < 0.0005, R 2 = 0.97), with a slope of −0.1635 (95%CI -0.1994 to −0.1276) and an intercept of 333.1882 (95%CI 261.1155 to 405.2608).

The correlations between “behavioral apathy” scores and signal change as P (yes) increased were still highly significant after controlling for individuals akaike information criterion (partial correlations, SMA: r = 0.562, P < 0.0005; ccz: r = 0.555, P < 0.0005; and M1: r = 0.489, P = 0.002).

In contrast, PMA triggered a much larger increase in the C/N ratio of eERK-KTR1.2/emiRFP670, from ∼0.7 to ∼1.7, which was highly significant ( p = 5 × 10 −4 ).

A highly significant reduction in interleukins-6 (IL-6) (standardised mean difference (SMD) = 1.32 (95% confidence interval (CI): 0.58, 2.06), Z = 3.48, P = 0.0005), a significant reduction in tumor necrosis factor-alpha (TNF-α) (SMD = 1.29 (95% CI: 0.19, 2.39), Z = 2.30, P = 0.02) but no change in overall C-reactive protein (CRP) (SMD = 0.40 (95% CI: -0.26, 1.07), Z = 1.19, P = 0.23) levels were observed by using the random-effects model.

For the ADH3 gene, the ethanol and galactose media were highly significant (each p ≤ 0.0005) in comparison to glucose, which has zero effect by parametrization.

In all figures, we marked the permutation test results as follows: If the number of failures was, for example, 1 in 10,000 ( p = 0.0001) or less, it was marked as highly significant (***), 5 in 10,000 ( p = 0.0005) or less, as significant (**), and 10 in 10,000 ( p = 0.001) or less, as weakly significant (*).

Considering the influence of drinking water source, reduction in Campylobacter occurrence for using tube-well water in comparison to river water was observed to be highly significant (p < 0.0005) in cloacal swab samples and significant (p < 0.005) in egg surface swab and drinking water samples but insignificant for soil samples (Fig. 4 B).

In the second 5-minute bin (5–10 min), ordinary one-way ANOVA showed a highly significant effect (F (3,22) =8.825; *** p=0.0005).

For all tumors, there was a highly significant association between the Immunotype Score and the expression of PTPRC (r = 0.32, p = 0.0005, Fig. 2 A, Table 1 ).

The difference between MAE and BAE genes remained highly significant ( π = 6.2×10 –4 ±4.8×10 –5 for MAE genes in the global population, 5.1×10 –4 ±3.5×10 –5 for BAE genes, p < 5×10 –4 , see Fig.1c ).

A highly significant binomial GLMM (χ 2 ML = 33.24, N obs = 196, P < 0.0005; Table 1 ) revealed that, while controlling for the potentially confounding effects of age, sex, group size, the number of zoos a subject had lived in, and task identity, Sumatran subjects were significantly more likely to solve a task than their Bornean congeners (B = 1.934, SE = 0.74, z = 2.63, P < 0.01, Fig. 1 , Table 1 ).

Differences were highly significant ( P < 0.0005).

An initial overall confounder-adjusted MANOVA test for expression in 13 immunity genes revealed a highly significant difference (main effect) between wild and mesocosm fishes ( F 14,256 = 3.72, P <0.0005).

CIN showed a higher abundance on protein level in every cell line cultured under serum-free conditions and the difference in protein levels between the culture conditions was highly significant (Fig. 1f , p < 0.0005).

The difference in level of relatedness between breeding pairs and random pairs was estimated at 0.07 and was highly significant (10,000 simulations, one-sided p -value = 0.0005).

For MCP 0 in the sMRI‐sFNC pair, all of the comparisons are highly significant compared to the other clusters: MCP 1 ( p < 0.0005) and MCP 2 ( p < 0.0005).

Results obtained from PLS-DA ( Figure 2A ) revealed that metabolic features formed distinct clusters (15 cells in each group), and this difference was highly significant ( p = 5 × 10 -4 ; permutation test in Metaboanalyst 3.0).

The np-MANOVA based on the first two coordinates of individuals in MDS clearly demonstrated highly significant differences between sexes ( F = 175.89, P = 0.0005) and marginally significant differences among populations ( F = 1.95, P = 0.07).

Serum MDA levels were found to be higher (6.846 ± 1.5) than controls (4.588 ± 1.17) while SOD levels were found to be lower in women with miscarriage (2.26 ± 0.66) than that of control group (3.16 ± 1.13) and difference were found to be highly significant ( P = 0.0005, <0.0001), respectively.

In contrast, selection for the BCDO2 locus became highly significant ( s = 0.0060, P = 0.0005) in models without migration, confirming that unaccounted gene flow can cause spurious effects in selection analyses.

The age adjustment was highly significant (p<0.0005), with an estimated mortality increase of 13.7% (95% CI 7.4% to 20.3%) for each 1% increase in %≥65.

6 ) and PLS-DA model validation by permutation tests was highly significant (p < 5e-04).

Using the cohorts from PARIS and Canada and the ExAC data set, the enrichment of rare CNTN6 variants in individuals with ASD compared with the general population was highly significant (ASD: 18/501; 3.59% controls: 535/33 480; 1.6% P =0.0005) and with an achieved power to observe such a difference of 87%.

GSH was proven to enhance the sensitivities of the bare SPCEs towards Cd 2+ statistically at a highly significant level ( p = 0.0005). 33 Intriguingly, however, the sensitivities to Pb 2+ and Cu 2+ did not show any significant difference.