“highly significant”

Normo-weighted subjects showed a highly significant decrease in periodontal inflammation (PISA index) (986.99 mm 2 ± 591.47 vs. 477.28 mm 2 ± 542.55, p = 0.0007) after periodontal treatment, shifting from a severe state of periodontitis to a mild state of periodontitis ( Figure 3 ).

Further the haplotype C/C/C/C/T/1 can be considered as an extended protective haplotype as it was found in 31.9% in the controls when compared to 11.6% in ESRD with highly significant P value ( P = 0.0007) [ Table 3 ].

The correlation was highly significant with a Pearson correlation coefficient ( r ) of −0.41 and p = 0.0007.

The caffeine–MoCA association remained highly significant in the E3/E3 homozygous subgroup ( n = 45, p = 0.0007), demonstrating robustness to genetic stratification and ruling out confounding by APOE -related differences in caffeine metabolism or cognition.

Although the interaction between baseline Ct and number of high Ct samples in the pool was not very strong ( P =0.014), the interaction between baseline Ct and number of low Ct samples in the pool was highly significant ( P =0.0007), as shown in Figure 2 .

For the multi-rate stimulus ([1234]; compare filled orange triangles), all participants, with the exception of MED06 and possibly MED05, assigned higher pitch ranks to the LD than to the SD version, and this difference was highly significant at the group level ( t (7) = 5.79, p = 0.0007**, d = 2.0).

However, while the differences in age effects between control and case piglets were highly significant ( p = 0.0007, 0.0001, 0.0004), the three estimated positive slope values for diarrhoeic piglets were not significantly greater than zero ( p = 0.11, 0.39, 0.12).

Postoperative visual analog scale score was 4.8 ± 1.12 in Group BN, and in Group BF, it was 3.86 ± 1.04 which was statistically highly significant ( P = 0.0007).

The interaction between AgNO 3 concentration and temperature (AD) was highly significant ( p = 0.0007, F = 16.35), suggesting a strong combined effect on ZP.

The study showed a highly significant reduction in recurrence ( p = 0.0007) without any adverse effects. 55 Although small, this trial provided early safety data and suggested potential efficacy, paving the way for larger investigations.

For TPC, the quadratic model was highly significant (F = 32.20, p = 0.0007; Table 2 ), indicating that the model adequately describes the relationship between extraction variables and phenolic recovery.

There was also a highly significant difference in the minimum CT values between the tumor recurrence and granuloma groups (15.67±5.113 vs. −17.17±4.826, P=0.0007) and in the floating range CT values (148.00±5.471 vs. 88.11±7.671, P<0.0001), respectively.

For instance, within the CPS ≥ 20 population, pembrolizumab monotherapy compared to EXTREME resulted in a net gain of 4.2 mo in terms of OS (14.9 mo vs 10.7 mo) with a highly significant 39% reduction in risk of death (HR = 0.61, P = 0.0007).

Further, in analyses of the GTEx (Genotype Tissue Expression) human post-mortem dataset containing samples from 53 non-diseased tissue sites for nearly 1000 individuals, we observed a highly significant correlation between GHR and MITF expression in sun-exposed (lower-leg; Pearson coefficient = 0.19, p = 0.00071) and not sun-exposed (suprapubic; Pearson coefficient = 0.25, p = 0.00011) normal human skin ( Figure 7 B).

There was no significant interaction of condition and night for the ON-OFF difference of all windows with more than two stimulations ( F cond x night (6,141.8) = 1.62, p = 0.15), the main factor condition was highly significant ( F cond(1,12.6) = 19.76, p = 7.1 × 10 −4 ) indicating that the lowSWA enhancement was persistent across 7 nights.

However, we noted a highly significant interaction between line and diet in terms of final body weight ( P = 7.10 –4 ), specific growth rate ( P = 8.10 –3 ) and voluntary feed intake ( P = 5.10 –7 ).

Interestingly T→C mutations show even stronger strand asymmetry among phenotypic mutations, and are over-represented to a highly significant degree in the sense strand (P = 0.00071), but are not over-represented among incidental mutations.

Subsequently, CYPRI_cor was applied to the same patient cohort and yielded markedly stronger results, showing a highly significant association with the outcome measure IMPACT_orig (SE = 0.22; p = 0.00072), suggesting that the revised score maintains and potentially strengthens the relationship between CYPRI and clinical impact ( Figure 4 ) compared to the original model ( p = 0.0267).

Moreover, miR-374b was found to have highly significant overall complementarity with the consensus sequence ( P <7.3e−04).

Similarly, levofloxacin resistance was observed in all EEC isolates (100%, n = 53) but in 81.0% ( n = 34) of APEC isolates, showing a highly significant difference ( p =0.000731).

Overall, the interaction between MeAnSpring and MAT levels was also highly significant (LR Chisq = 14.4, P -value = 7.4e−4), suggesting DOY is dependent on the interaction between the interannual spring variation (e.g. anomalies) and the local historical temperatures from 1895 to 2022.

In the case of TNF stimulation, dasatinib caused a modest but statistically significant ( P = .013, n = 9) inhibition at as little as a 50nM concentration, whereas in case of C5a stimulation, a robust and highly significant ( P = .00074; n = 6) inhibition was achieved by 100nM dasatinib.

The statistical difference in endosome diameter between FUSwt and FUS501 was highly significant ( P -value=0.00074), but only a tendency between wild-type and FUS501 ( P -value=0.098) ( Fig. 4 B).

The overlap of ECACC-6 with Nf1 -Mouse-12 was highly significant ( P = 7.5 × 10 -4 ) as well as the overlap between two human groups ( P = 1.2 × 10 -3 ).

The association between this variant and ACR levels also remained highly significant in the replication study ( p -value = 0.000751).