Interestingly, we found a highly significant ( P < 0.001) increase in nuclear CUG-foci frequency in DM1 fibroblasts derived from two different patients (DM1 and DM1′) upon knockdown of DDX6 (foci elevated from 4.4 ± 0.28 and 7.9 ± 0.34 foci per cell respectively, to 7.1 ± 0.48 and 9.7 ± 0.37 per cell, respectively) (Figure 2A and quantified in Figure 2D ).
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Table 3 shows that the association between year of the study and PHQ scores was highly significant ( P < 0.001).
The difference in the overall scores of resiquimod-induced and control wounds was highly significant, with p < 0.001.
Apart from deviating from a standard neutral model, some loci pairs (1813, 1955) had positive LD (D′) results with highly significant ( p < 0.001) χ 2 values of 19.7 and 12.7 among Homa Bay and Kisumu sequences, respectively ( Supplementary Table S1 ).
In a pairwise comparison (independent samples t -test), the between-group difference of the MCS for HM and PCM was significant ( P =0.02) and highly significant for the differences between HM and carers, PCM and doctors, PCM and carers, and doctors and carers ( P <0.001).
Results: There was a highly significant increase in a protein expression of PDFG-B in all cases of acute and chronic venous thrombosis compared to the control group with P < 0.001; furthermore, it was more specific than DD for the detection of DVT (specificity 95% and 90%, respectively).
However, the overall response was highly significant (Z = 7.839, P < 0.001).
There was a highly significant effect of a positive history of seizures on the CDR-SB towards abnormal over disease duration (history of seizures*disease duration: F = 18.66; p < 0.001) (Fig. 2 ).
The results showed highly significant effects for the covariate familiarity, F (1) = 58.84, p < .001, as well as the factor metaphoricity , F (1) = 12.188, p < .001.
The result was highly significant with a P < 0.001.
This correlation is highly significant ( p < 0.001) as gauged by a permutation test ( see Materials and Methods ).
All patients with acute infarction on the presenting CT scan had poor outcome in our study, and hence, this factor was highly significant as a predictor of poor outcome (OR could not be calculated, P < 0.001).
This CTT difference between both the groups is highly significant ( P < 0.001).
For each of the 1000 sub-sampled trials, the divide between freshwater, marine, and terrestrial environments was highly significant and explains much of the variation (ANOSIM ranges: p = 0.001 to 0.005 and R = 0.65 to 0.60).
macrocarpa individuals, the hierarchical nuclear genetic differentiation between the two species based on this clustering pattern was the strongest and highly significant ( F CT = 0.288, P < 0.001).
The difference in the percentages of sand flies entering the two types of treated bednets was highly significant (c 2 = 114.9, p <0.001).
In adjusted analyses, the model was found to be highly significant ( p < 0.001).
The relationship between tree size and hollow presence was highly significant in our model (Wald statistic = 388.1; P <0.001).
However, when analyzed on cluster level, principal component analysis (PCA) revealed highly significant segregation of the immune profiles before and after hookworm infection (Fig. 2B , PERMANOVA P < 0.001).
Differences were considered significant at P < 0.05(*) or highly significant at P < 0.001 (**).
The expression profile of TLRs in neck of femur and OA cartilage revealed a highly significant ( P < 0.001) downregulation of TLR2 and upregulation of TLR3.
0.5 mM) resulted in a highly significant increase (P<0.001) compared to the solvent-only control (n = 10, SEM = 0.20, d.f. = 45, CV = 19%) ( Fig. 3a ).
3.3 Regulation of NMDA and AMPA receptors in the hippocampus Flavonoid intervention induced highly significant increases in the levels of the NR2B subunit ( F 2,17 = 10.843, p < 0.001), for both the 8.7 mg dose ( p < 0.05) and the 17.4 mg dose ( p < 0.001).
A highly significant correlation was observed with TPC (R 2 = 0.9312 ***, p < 0.001) and moderate correlation with TFC (R 2 = 0.8158 **, p < 0.01) ( Table 4 ). 2.4.3.
After adjustment for age and sex, highly significant results remained ( P <0.001) (data not shown).