“highly significant”

We verified this by testing the overlap between the TF motif-gene cis -regulations inferred by MLC as applied to the LiCAT-seq human embryonic development dataset, 38 and the cis -regulations inferred by MethCorTarget applied to the DNAme human embryonic development dataset 39 : we found a highly significant overlap, odds ratio OR = 13.3 ( 12.9 − 13.8 ) ( p < 0.001 , Fisher’s exact test).

Management method significantly affected BD and SP ( p < 0.05) but not MC, while management duration exerted highly significant effects on all three parameters ( p < 0.001) ( Figure S1 and Table S1 ).

Quantitative comparison of the total dendritic length (TDL) indicated a highly significant reduction in the dendritic tree in injured MNs (TDL of control, 10379.7 ± 1099.8 μm, n = 11; TDL following CP crush, 4718.3 ± 742.3 μm, n = 11; P < 0.001, paired Student's t test; Fig. 10 C and E ).

Results Highly significant (p < 0,001) correlations were found between CD117 immunostaining patterns and histological grade, cell proliferation markers (Ki67, AgNORs) and tumoral necrosis.

However, there was a highly significant difference in the total scores according to the presence or absence of AOS (p < 0.001), and while the inter-rater reliability for some individual items was low, the inter-rater reliability for the total score was high at an excellent range.

Procedural access routes As detailed in Table 2 , there was a highly significant difference in the type of vascular access used across the three device cohorts ( p < 0.001).

However, PCT levels demonstrated a highly significant decrease over time ( p < 0.001).

Furthermore, the individual slopes relating autoMAPSE to MAP were highly significant ( P < 0.001) and markedly heterogeneous (both positive and negative), suggesting that ventriculoarterial coupling differs substantially in different individual patients.

A highly significant extreme overall genetic differentiation was found among samples ( F ST = 0.716; p<0.001).

We found that 95.2% of all truncating variants were associated with severe phenotype; this association was highly significant ( p < 0.001).

This difference was highly significant (bootstrapping test confirming more similar fixation maps within than between fixation classes, p < .001).

A highly significant association was observed between pregnancy-risk status and teratogenic medication use (χ2(1)=12.89, p<0.001).

Overall, it appeared that more synaptic input to GRPR cells was derived from excitatory interneurons that primary afferents, and this effect was highly significant ( p < 0.001).

Highly significant interactions ( p ≤ 0.001) were found among the tested rootstocks and locations regarding vegetative growth parameters, except for the trunk diameter index.

ΔR 2 ranged from 0.508 (for ITS) to 0.759 (for PU), with all F‐change statistics highly significant (p < 0.001), indicating these constructs explain an additional 50.8 to 75.9% of variance over and above controls.

Studies comparing the highest versus lowest quartiles of UPFs intake ( n = 3) ( 16 , 17 , 23 ) yielded a highly significant and consistent result (ES = 1.23, 95% CI: 1.14–1.32, p < 0.001).

For E P and E , one-way ANOVA revealed highly significant differences ( F = 40.59 and F = 19.13, respectively; both p < 0.001).

Moreover, even though all three experiments were carried out under the same greenhouse conditions, ANOVAs showed highly significant differences ( p < 0.001) between the replications.

The results showed Giardia infection in all examined regions of Serbia, with an overall prevalence of 6.1 %, and highly significant (p = 0.001) differences among regions (3.2-14.2 %).

Of these genes, six were identified as having highly significant matrix scores for the presence of an HRE (p < 0.001) ( Fig. 2 ).

There was a highly significant progressive increase in mitochondrial mass from culture days 1 through 6 ( Figure 3A ) [One way ANOVA: F(4, 15) = 136.76, p<0.001].

However, training demonstrated a highly significant effect ( P < .001), as practitioners who received training scored higher (mean = 70.91, SD = 3.335) compared to those without training (mean = 62.72, SD = 2.963).

Linear regression indicated that both PFOA concentration and culture time are highly significant predictors for both α and M ( p < 0.001 for all).

The percentage of degenerated fibers showed a highly significant decrease in this group (7.74 ± 0.66, p <0.001) compared with the FEN group.

In contrast, grouping factors including species and treatment explained as much as 74.79% of the variation in fungal communities, with a highly significant effect ( R 2 = 0.7479, p = 0.001).