Comparison with our cohort shows a highly significant shift in subtype (p < 0.001 by Chi-square) Comparison of CD4 counts at presentation between CRF01_AE and B showed a significantly lower count (233 cells/mm3 vs 350 cells/mm3, p = 0.03 by T-test) despite no difference in age (p = 0.15), and self-reported time to acquisition (p = 0.66).
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The overall composite mean target difference between P1 and P2 was highly significant p < 0.001 EGDT substantially reduced time to antibiotics (1hr 55 mins in P1 vs 1hr 13 mins in P2 p < 0.001), IV fluids and blood were more frequently given to shocked patients; airway placement in coma was more likely.
The Pearson’s correlations between the kappa scores and number of genes harbored in the enriched modules were − 0.947, − 0.983, and − 0.914 for Control_MIH, Control_Fresh, and Control_SPH respectively, and were highly significant (P < 0.001).
All approaches gave a highly significant effect of BMD on fracture incidence ( Table 5 ) ( p -values of < 0.001 ).
The majority of correlations showed highly significant p-values ( p < 0.001), supporting the robustness of the findings.
23 Statistical significance was defined as P ≤ .05 (highly significant if P ≤ .001).
Collaboration demonstrated highly significant and positive associations with its subscales: Cooperation (r = 0.780, p < .001), Partnership (r = 0.710, p < 0.001), and Coordination (r = 0.704, p < 0.001).
The correlation between the number of nematodes inserted and the number of nematodes detected by BSPIM was highly significant (linear regression R 2 = 0.9903; Spearman rank-order correlation p < 0.001, n = 5; Fig. 4b ).
Spearman correlation test showed that there was a close and highly significant relationship between serum level of B1R with histological staining of B1R in stroke patients (r=0.54, P<0.001) ( Fig. 4A ), TIA (r=0.81, P<0.001) and asymptomatic patients (r=0.61, P<0.001), suggesting of a notable correlation between changes in serum B1R level and changes in plaques in the progression of atherosclerotic plaques.
The effect of claim type on the knowledge-updating index was highly significant, F (1, 28) = 15.85, MSE = 0.17, p < .001, η 2 = .36.
The Chi-squared test showed a highly significant difference across ethnic groups (χ 2 =123.165; P≤0.001).
When the earliest cohort (1981) was compared with the post‐collapse cohorts (2006–2008), a sharp increase in genetic differentiation was evident ( F ST = 0.042–0.072; all pairwise comparisons highly significant, P < 0.001; Fig. 3 C).
Similar results were obtained with the Aster framework: The interaction between population and planting habitat was highly significant (χ 2 = 1239, df = 14, P < 0.001) in the full model, and population terms were significant in separate models by planting habitat (χ 2 = 1757, df = 14, P < 0.001 and χ 2 = 986.7, df = 14, P < 0.001 in the roadside and scrub, respectively).
Among derived ratios, PLR showed a highly significant difference between groups (149.72 ± 75.93 vs 78.03 ± 28.95, P = .001), and the effect size was large (Cohen’s d = 1.35, 95% CI: 0.76–1.94), indicating a strong discriminatory potential.
The likelihood ratio test was highly significant ( P < 0.001), confirming the overall model fit.
The species‐wide heterozygote deficit was highly significant ( P < 0.001), but low ( F IS = 0.05 for M. sieversii , F IS = 0.06 for M. orientalis ).
The blue module exhibited a highly significant positive correlation with ASA ( P < 0.001) and significant correlations with Pro and H 2 O 2 , while the turquoise module showed significant negative correlations with ASA and H 2 O 2 ( P < 0.001) and Pro ( P < 0.01).
Notably, Table 1 shows that tube voltage and tube current–time product exhibited highly significant differences between veterinarians and keepers (both P <.001), whereas the difference in Hp(10) was modest ( P = .006).
In ANCOVAs controlling for trait anxiety, group differences in λ remained highly significant in models that included ( F 2,57 = 7.5, p = 0.001) and omitted ( F 2,70 = 9.0, p < 0.001) study site as a factor.
On comparing the three levels for intra-group comparison, there was a statistically highly significant (P-value ≤ 0.001) difference, primarily due to the difference between the 1 mm level (highest mean reduction) and the 5 mm level (lowest mean reduction).
Both interventions led to highly significant improvements in all domains of subjective well-being (emotional, psychological, and social) and the Total Subjective Well-being score from baseline ( p < 0.001).
24 In this study, a considerable placebo effect was observed for pain, daily activity scores, and overall WOMAC scores, and although improvement relative to baseline was highly significant ( P < .001– P < .03), the difference to placebo did not reach significance level in any case.
Both word count and average sentence length differed significantly across sentiment categories (Kruskal–Wallis H -tests, p < 0.001), with Dunn's post-hoc tests revealing that all pairwise comparisons between Negative, Neutral, and Positive posts were highly significant ( p < 0.001).
Notably, a highly significant association was found between HPV status and surgical intervention ( p < 0.001).
ADC showed a strong and highly significant inverse correlation to microvascular density (CD31, ρ = −0.80; p < 0.001) but no significant correlation to proliferation (Ki-67, ρ = −0.42; p = 0.061). ∆TTL and ∆ADC showed strong and significant inverse correlations (ρ = −0.75; p = 0.002).