“highly significant”

This difference was highly significant (corrected p -value < 0.001) in 15 of 17 patients (88%) for both cumulants and less significant (corrected p -value < 0.01) in the other 2 patients.

The differences were highly significant for non-migrated cells as well as for PMN after random migration and stimulation with fMLP (all p < 0.001, see Table 1 ).

For Engagement, the U statistic was 2034.00 with a Z-score of − 3.97 and a highly significant p -value ( p < 0.001), below the critical value (Ucrit = 2580).

Statistical significance thresholds were established as follows: * P<0.05 (significant), ** P<0.01 (highly significant), and *** P<0.001 (extremely significant).

Comparing the Kaplan-Meier survival curves, only rCBV and rCTH in the enhancing tumor and rCTH in a combined region consisting of enhancing tumor and edema are associated with TTP and OS, where predicting OS by means of rCTH is highly significant (p < 0.001).

LPS stimulation as well as incubation with lambda-carrageenan resulted in highly significant induction of TNF-α transcription compared to unstimulated control (p < 0.001 for LPS stimulation and lambda-carrageenan).

The ANOVA result remained highly significant ( p < 0.001) when considering the valence dimension as well.

In standard (atropine sulfate), reduction in mean distance travelled by charcoal meal was highly significant ( P < 0.001) as compared to control and % inhibition of motility was 59.86.

Highly significant associations were found between duration of acne, post-acne hyperpigmentation, and grade of acne with DLQI scores (all p<0.001), showing that longer duration, hyperpigmentation, and higher grades of acne significantly worsened QoL.

The striking difference between the groups (Figure 2 and Table 2 ) is the lower accuracy of high-PRVS participants, and this effect is highly significant [low-PRVS = 97.3, high-PRVS = 94.1, F (1, 26) = 16.010, p < 0.001, η 2 p = 0.381].

Similarly, those without PGx training have an OR = 0.257 (95% CI: 0.134–0.490, p < 0.001), meaning they are significantly less likely to have good knowledge compared to those with training (highly significant, p < 0.001).

The effect of variety on acrylamide formation was highly significant ( p < 0.001).

The standard statistical significance levels associated to p values were adopted: significant (p < 0.05), very significant (p < 0.01), and highly significant (p < 0.001).

The control group also has denser connections that are typically of higher significance compared to the rifampicin group; however, all correlations are highly significant in this network ( r>0.65, p<0.001 ).

A Kruskal–Wallis test among genotypes indicated a highly significant difference (χ 2 3 = 47.87, corrected p<0.001), as did Wilcoxon rank sum tests between WT and lox2/3 , and WT and lox2/3 x TPS10 (W 24,12 = 0, W 24,11 = 0 and corrected p - values<0.001, Figure 1C , Figure 1—source data 3 ).

Furthermore, a highly significant (P < 0.001) over-expression of AGR3 protein in G1 and G2 breast tumours compared to normal breast tissues ( Fig. 2G ) was detectable as well.

In the “Out-of-sample validation” section, the text “we obtained digitised maps of AADT” has been amended to “we obtained digitised maps of AADT (work day averages)”; the text “27 and 87 empirical AADT values” has been amended to “28 and 87 empirical AADT values”; the text “highly significant ( p < 0.001) and positive (0.60 and 0.70, respectively)” has been amended to “highly significant ( p < 0.005) and positive (0.55 and 0.70, respectively)”; the text “The percentage of observations that fell within the 90% prediction interval was 85.2%” has been amended to “The percentage of observations that fell within the 90% prediction interval was 89.3%”; and the text “These percentage dropped to 63.3% and 77.4%” has been amended to “These percentage dropped to 63.6% and 77.4%”.

Thus, PCI showed a highly significant association with the length of stay, with a p-value <0.001.

Furthermore, Language exhibited a highly significant statistical association (χ2 (1) = 25.50, p < 0.001), with the English group demonstrating significantly lower productivity than the Chinese group (β = −1.034, SE = 0.205, p < 0.001).

Results The response of the bacterial assemblages to environmental factors The combined effect of elevation, cushion habitat, and soil physico-chemical parameters on composition of bacterial assemblages derived from CE-SSCP profiles explained 55.2% of the total data variation in Nubra, which was highly significant (db-RDA, P < 0.001).

Finally, the seasonal moving-average component (MA(12)) is highly significant (coefficient = − 0.821, p < 0.001), with a tight confidence interval from − 1.056 to − 0.586, entirely below zero.

Over two experiments of 10 mice in each experiment (total of 20 mice and 40 oviducts assessed), we consistently observed a highly significant reduction in the rate of hydrosalpinx (Table 1 , P < 0.001, chi-square analysis with Yates correction), when compared to historical controls and a slight but statistically significant drop in the rate of hydrosalpinx in the BALB/c susceptible strain ( P < 0.04).

For ethanol–water mixtures, Δt2 significantly decreases with increasing temperature across most concentrations, with several comparisons showing highly significant p -values ( p < 0.001).

The superiority of the two-factor model over the single-factor model was further supported by a lower Akaike Information Criterion (AIC) value for the two-factor model (AIC = 4376.1) as compared to the single-factor model (AIC = 4712.9) as well as a highly significant model comparison (Δχ 2 (1) = 1238.8, p < .001).

On multivariate analysis, previous stroke/transient ischaemic attack/thromboembolism was a predictor of higher risk of stroke, death and the composite of ‘stroke and death’, while VKA treatment was a highly significant predictor of a lower risk for death (adjusted HR 0.46, 95% CI 0.28 to 0.74, p<0.001) and the combined end point of death or stroke (adjusted HR 0.64, 95% CI 0.43 to 0.96, p=0.003).