“highly significant”

Log of likelihood ratio contrasted by the χ 2 test demonstrated that the model was highly significant (χ 2 = 21.02; degrees of freedom [df] = 4; P < 0.001).

This observation was highly significant compared to the expected number of interactions with neighboring genes in a randomized network that preserves node degrees ( P < 0.001; empiric P -value).

Smooth term analysis indicated that temporal trends were highly significant in the polluted site (Ambient, polluted: edf = 5.777, p < 0.001; Warmed, polluted: edf = 5.818, p < 0.001), but were non‐significant in the non‐polluted site (SI Table S16 ). 3.2.4 Green Microalgae Concentration For green microalgae, only the June data provided sufficient variation to fit a GLM; on all subsequent sampling dates, concentrations were essentially zero.

There were also highly significant correlations demonstrated between MSS and NED colonoscopy comfort score ( P < .001), polyp detection rate ( P < .001), and cecal intubation rate ( P < .001).

Within-group analysis further confirmed that the improvement in the PVA-HA group was highly significant at every follow-up visit compared with their own baseline ( P < .001).

At 24 h, all four cell lines showed NIS expression and iodide uptake at MOI 1, with a highly significant difference (two-way ANOVA P <0.001) compared with cells treated with the competitive inhibitor of iodide uptake (potassium perchlorate) ( Figure 2c ).

Molecular mapping of QTLs associated with seed-Fe and Zn concentrations A highly significant difference (P < 0.001) of seed-Fe (51.3 ± 5.0, 40.3–67.0 ppm with 81% H 2 ) and Zn (36.0 ± 3.8, 27.9–48.5 ppm with 83% H 2 ) concentrations in two parental accessions and 277 individuals of a RIL mapping population [ICC 4958 (Fe: 43.0 ± 2.9 and Zn: 30.2 ± 2.5 ppm) × ICC 8261 (Fe: 64.8 ± 3.3 and Zn: 42.0 ± 2.7 ppm)] across two years based on ANOVA was observed ( Table S3 , Fig. 3A,B ).

Significant postoperative improvements were observed in range of motion (from 73.2 degrees preoperatively to 104.3 degrees postoperatively), OKS (from 14.3 to 29.2), and KSS (from 48.2 to 74.9), all of which were highly significant (p < 0.001).

The highly significant p value (p < 0.001) further supports the conclusion that surgical treatment results in substantially faster resolution of trigger thumb than conservative management.

Reproducibility of the measurement was highly significant for interobserver variability (intraclass correlation coefficient [ICC]=0.918, p <0.001).

The difference in behavioural skills between episodes was highly significant, with participants rating their abilities in taking medication lower for the non-adherent episode ( p < .001; d = 0.91, large effect).

We included seven HIV-1 integration site data sets for this analysis: two derived from this study (data sets of the same cell type combined; n = 1,484) and one other MDM data set (n = 754) and four other CD4 + T cell data sets (n = 4,613) obtained elsewhere 14 , 18 , 31 , 32 , 33 ( Table 2 ), By comparing the frequencies of HIV-1-hosting genes linked to clonal expansion of latently HIV-1-infected CD4 + T cells in gene hotspots and genes with single HIV-1 integration events, we observed a highly significant increase of genes linked to clonal expansion of latently HIV-1-infected CD4 + T cells in gene hotspots in CD4 + T cells (2.5×, p < 0.001), but not in MDMs ( Fig. 5b ), showing again that the repertoires of genes accessible to HIV-1 for integration in the two cell types were distinct.

Inter-rater reliability yielded highly significant correlations ( p < 0.001).

Regional GDP has a positive and highly significant impact (0.1687, p < 0.001), indicating that higher regional economic performance increases rental prices, reflecting the influence of economic conditions on housing demand.

GraphPad Prism version 8.0 (CA, USA) was used for the analysis, and significant differences were assessed using one-way ANOVA followed by Tukey’s post-hoc test (significant at p < 0.05, very significant p < 0.01, and highly significant p < 0.001).

The model demonstrated exceptional fit with a pseudo R 2 of 0.450 and a highly significant likelihood ratio test ( P < 0.001), indicating that the model explains 45% of the variance in TBP diagnosis.

This difference was highly significant (GLMM F 1,-398 = 15.42, p<0.001), but there was no influence of emotion type (F 1,-397.3 = 3.23, p = 0.07), familiarity (F 1,-397.3 = 1.03, p = 0.31) or area of interest (F 1,-397.3 = 3.68, p = 0.3).

Improved semantic accuracy: All models showed a highly significant improvement in verb semantic accuracy (Semantic Accuracy-V) and comprehensive semantic accuracy (Semantic Accuracy-C) ( p < 0.001).

Quantitative analysis revealed highly significant differences in spermidine levels between OIPN and CONT groups across all nutritional strata: in the whole cohort ( Figure 3F , p < 0.001), the malnutrition group ( Figure 3G , p < 0.001), and the well-nourished group ( Figure 3H , p < 0.001).

Stent assisted coiling resulted in a highly significant increase of the inflow angle α from a mean value (SEM) of 119° (±6.5°) pretreatment to 130° (±6.6°) posttreatment (P ≤ .001).

Similarly, comparisons against LightGBM (our strongest non-neural baseline at 0.841 accuracy) demonstrate highly significant advantages ( p < 0.001, 95% CI: [0.046, 0.056]), validating claims that multi-modal fusion provides meaningful benefits beyond optimized gradient boosting approaches.

We found highly significant correlations of both SCPs with full-scale IQ ( r = 0.286, left, p < 0.001; r = 0.242, right, p = 0.001), again in contrast with every other tract (Benjamini–Hochberg corrected; Supplementary Table S3 ), confirming the critical role of the cerebellum in cognition ( Broussard, 2013 ).

The difference in number of isolated pancreatic islets between genotypes was statistically highly significant (WT 303 ± 7.3, Wfs1HZ 176 ± 14 and Wfs1KO 80 ± 7.5, P < 0.001) (Fig. 1 ).

Another result to highlight is the highly significant difference between cases and controls regarding the mean number of risk alleles at the 14 selected adenoma susceptibility loci (p<0.001).

1C ; Supplementary Table 1 ), and most correlations are highly significant ( p < 0.001), justifying metric use in real-data comparisons.