With Affymetrix microarray technology, differential expression values greater than 1.7 are likely to be significant, based on internal quality control data.
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Thus, travel distance, cost, and the time involved are likely to be significant barriers to using a beach or river for physical activity for residents of disadvantaged areas.
Neither are chromosomal features likely to be significant factors.
Given that fold change is a component of the p-values generated by Agilent and Rosetta data analysis software, the overall effect of fold change on data correlation is likely to be significant as shown in Figure 4 .
These conserved microsatellites occurring among three or more homologous genes provides greater evidence that these CNMS are likely to be significant in gene regulation.
Transfer of genetic testing to diagnostic laboratories may make genetic testing more widely available but the costs of analysis are likely to be significant and may prevent accessibility to confirmatory genetic testing in many situations.
Risk compensation may be especially important for MC because avoiding the sexual dissatisfactions of condom use and the desire to have more sex partners are likely to be significant motivations for men to seek circumcision [ 7 ].
This is likely to be significant as social traits are thought to be important in determining both the virulence and persistence of pathogenic microbial infections [29] , [30] , [31] .
We speculate that the interesting patterns are those that fail to track patterns of A+T-richness; for example, repeat sequences in non-coding regions enriched for G and C are the ones more likely to be functional and understanding the components of codon bias that is not related to A+T-richness is more likely to be significant.
Nevertheless the trial has stopped and it is still likely to be significant.
First, we recognise that other enzymes of the aspartyl, cysteine and serine proteinase families and their specific inhibitors are also likely to be significant participants in ECM remodelling during cancer progression.
As the tumours in our study all regressed on chemotherapy, these studies all suggest that there are likely to be significant errors in the clinical measurements that will not lessen as the tumours shrink.
While it has been suggested that, for myocardial (37) and muscle (23) capillaries, the aggregate filtration coefficient for endothelial cells for water may be comparable with or even greater than that for the "small pores" (32), the contribu- tion of the permeability to water of the podocyte plasmalemma hardly seems likely to be significant for glomerular filtration, since the glomerulus has a hydraulic conductivity 40 500 times greater (11, 14) than that of muscle capillaries.
Therefore, we feel that while the mean lengths we have determined for the different c~-actinin isoforms may not necessarily repre- sent their absolute values, the relative length differences are likely to be significant since they are based upon common preparation and evaluation protocols.
The involvement of phosphoinositides in the activation of actin assembly sites is likely to be significant for the spatial and temporal regulation of actin dynamics, because many signaling pathways are mediated through the lipid kinases that control the level and distribution of specific phospholipids (for review see Carpenter and Cantley, 1996 ).
Key correlates of sociality A variety of factors likely to be significant in the evolution of aphid soldiers have been identified.
Any synthetic effects involving the ARK1 or the PRK1 genes are likely to be significant since ark1 Δ and prk1 Δ single-mutant cells are very similar to wild-type cells in terms of appearance and growth.
A reasonable a priori conclusion is that the headgroup interactions with MPs are likely to be significant.
Together, these observations suggest that regardless of neurotransmitter phenotype, synapses are likely to be significant sites of agrin action.
The forces exerted on dynactin at centrosomes are likely to be significant since they involve large numbers of motor molecules operating on the entire microtubule cytoskeleton.
This is likely to be significant for the activation of the lipase as mutations in SLP-76 which block its ability to bind PLCγ1 lead to reduced TCR-induced PLCγ1 phosphorylation ( 42 ).
First, it suggests that the unexpected results we obtained for the function of ILK in Drosophila are likely to be significant for the functions of the ILK family as a whole.
This predicted site is likely to be significant considering the important role Nrl plays in rod photoreceptor differentiation [ 2 ].
Thus, in revising the MMT model, it was logical to examine the effects of a light-evoked decrease in [Na+]i upon the rods' Na''/ K+ pump.' The MMT model did not account for diffusion of K+ through the extracel- lular space, but such diffusion is likely to be significant.
<< K., the second term is likely to be significant since PH can be >> PK.