“likely to be significant”

The decision to utilize one or two plates is most likely to be significant for patients near their skeletal maturity and ultimately needs to be balanced with the cost of an additional plate.

Furthermore, at the continental scale, links between aboveground and belowground communities have a greater chance of being observed given that differences in plant traits and attributes are likely to be significant (Delgado‐Baquerizo et al ., 2018a ).

The panel highlighted that the consequences of CNS relapse, and its treatment, are likely to be significant and underrecognized.

Although further work is required to fully understand the complex cellular mechanisms of ICG uptake in tumour cells, there is likely to be significant variability depending on the cancer type, locality, grade, size, and vascularity.

Hypertension (OR: 13.5, p ≤ 0.05) and dyslipidaemia (OR: 11.8, p ≤ 0.018) were significantly less in RVHD patients and were more likely to be significant predictors for developing CAD (Table 4 ).

(1) coding regions-variants in coding regions are more likely to be significant.

While there are many factors determining whether a gene is activated or deactivated, it seems likely to be significant if the probability of a transcription factor is high for a branch of the phylogenetic tree and lower for the remaining species, or vice versa.

Discussion The most common neuroimaging finding in children with partial epilepsy from Indiais single enhancing lesions (SEL) with perifocal density suggestive of edema( 3 , 4 ).Wadia et al reported that 26.1% of Indian patients with focal seizures had enhancing ring or disc lesions visible in CT scans ( 5 ).The etiological spectrum of SEL in Indiaseems to be different from that described in the Western literature with infections like NCC and tuberculomas likely to be significant causes of ring-enhancing lesions.

As the inconsistency among different experimental data is still an unresolved issue, the uncertainty of EOS determined by experimental data is likely to be significant at high pressures and high temperatures. 3.4.

( 2002 ) who confirm the lowest coefficient of variation for M-LVID d (7.74%) among all the analyzed M-mode parameters; a low coefficient of variation was also found for M-LVID s (10.43%), so the authors suggest that for these parameters a change of over 10% is likely to be significant (Dukes-McEwan et al. 2002 ).

Favorable changes in risk behaviors were generally higher and more likely to be significant for individuals in the intervention group than for individuals in the control group.

Mutations in FAT1 are likely to be significant biomarkers in NSCLC, identifying groups of patients who do not respond well to ICIs and providing important scientific evidence for the development of personalized and precise immunotherapeutic regimens [ 81 ].

There are likely to be significant differences between the clinical research environment and typical health service settings, ranging from amenities (e.g. refreshments, available seating) to staffing (e.g. ratio of staff to clients, workload, salary) to time spent at the facility (e.g. waiting in general waiting rooms).

With regard to social factors, aspects such as the availability of sexual material (e.g., early exposure to pornography via digital media), negative attitudes towards sexual behaviour and simultaneous high-frequency behaviour or strong urges are likely to be significant.

We assessed the robustness parameter estimates, and whether there was likely to be significant differences between CT MAX evolution depending on nesting behaviour by conducting a bootstrap analysis with 1000 simulations as per Moen et al. 95 .

Thus, while surviving viral infection can reduce fecundity, this is only likely to be significant after the population peak.

This is due to the fact that as the sample size increases, the distribution of random errors becomes more stable, and the relationship between variables is more likely to be significant.

In addition, for increased survival times and an improved performance status, studies at the molecular biological level, including resistance mechanisms and targeted therapy (for example, antiangiogenic biologicals or trastuzumab in patients positive for HER-2), are likely to be significant issues in the future.

A difficult question for future studies is how does NOD2 function as an immune tolerance checkpoint, either in the context of Crohn’s disease or immune reactions to cancer? In the context of the findings here, how does lower NOD2 signaling increase tumor infiltration with effector CD8 T cells and the therapeutic immune response to anti-PD-1? The role of NOD2 in sensing the large commensal population of gut bacteria seems likely to be significant, since germ free mice treated with anti-PD1 mount a poor immune response to MC38 tumor cells that is restored by a defined gut bacterial mixture, with the restored response dependent upon CD8 T cells ( 64 ).

Intrapair correlation was consistently greater for MZ than for DZ pairs for both the inner and outer ratios, indicating that genetic factors are likely to be significant (MZ pairs share all of their genes whereas DZ pairs share approximately half; the shared environment, however, is assumed to be similar for both MZ and DZ pairs).

In our dataset - in which 96 hits were derived from a screen of 10,000 protocols - a triple hit from the same protocol would occur randomly once in every thousand repetitions of the experiment and therefore its occurrence in our screen is likely to be significant (i.e. indicate a highly effective protocol).

However, no attempt was made to estimate the social and economic consequences of AMR in Kazakhstan, even though they are likely to be significant.

The choice of cognitive task is likely to be significant in ensuring the reliability of the DTE.

Missing and incomplete data At each step there is likely to be significant loss-to-follow-up in this population.

This is particularly important as the burden of dual sensory impairment (hearing and sight loss) in symptomatic cCMV is unclear but likely to be significant.