“marginally significant”

The samples were split into two sets in order to save DNA and reduced genotyping costs: the first set ( n = 2,270 cases and 2,280 controls) was genotyped for all SNPs, and the second set ( n = 2,203 cases and 2,280 controls) were then tested for those SNPs that showed marginally significant associations in set 1 ( p -heterogeneity or p -trend < 0.1).

A broader composite outcome that added heart failure and transient ischemic attack yielded a marginally significant p value when comparing naproxen with placebo.

Fruit and vegetable intake was a marginally significant mediator of the relationship between education and high risk adiposity for women.

When the two year period of susceptibility for series A children was split into 'pre-natal' and 'post-natal' years highly significant ex- cesses of space-time interaction links were evident for each. Those occurring post-natally were slightly more marked. The analyses for younger series A cases (II - IV) show excess space-time linkages which are marginally significant Table II Analysis I.

.5) an = Number of animals at termination of study, bND = normal-Diet, percentage of total energy: 45%, 35%, 25%, 'mean (standard deviation), dp = 0.01, significant difference between the tumour volumes of all high caloric groups versus the respective low caloric groups, cp = 0.04, fP = 0.06, marginally significant difference between the tumour numbers of all high caloric groups versus the respective low caloric groups, gtime of dietary change, hweeks after dietary change, 'termination of experiment.

Peramelia showed a marginally significant correlation with phylogeny in all three topologies when size was included, but in none when size was removed.

A meta-analysis of case-control studies for heterogeneity from different groups may be marginally significant.

To our knowledge, however, such trend has not been reported in the literature to date, so we do tend to ascribe these marginally significant findings to random variation.

An overall com- parison stratifying for prognostic groups yields a marginally significant advantage rves for patients random to maintenance therapy (x2 = 432, P= ive maintenance therapy 0X04).

Examination of the total data revealed marginally significant differences between the "primary" and "secondary" groups, but significantly more pulmonary metastases in the "source" than in the "secondary" groups of animals.

We do not want to stress the marginally significant interaction with chewing of tobacco, as some false significant results might be expected with such a large number of tests for interaction.

There were also marginally significant differences in mean serum potassium and bicarbonate levels in those with and without hypophosphatemia ( Table 1 ).

Age effects were marginally significant for two genes, but not after Bonferroni correction, and furthermore would not have altered the significance of MFS status even if included.

The mice given marrow 5 days after irradiation showed an insignificant number of donor cells on the 12th day and developed only a marginally significant percentage of donor type cells by day 15 (10 days after marrow injection).

Although both Gad structural genes map to Chr 2 (16), they are positioned proximal to I11 in areas in which all markers typed to date havebeen NOD derived. Thus, NOD and NOR mice must be presumed to share the same Gad genes. Other PotentialRegions ConferringWeak Resistancein NOR. Presence of a weaker (and recessive or poorly penetrant) resistance gene on the more distal segment of Chr 4 was suggested by a marginally significant segregation distortion associated with the D4MitI1 and the naturiuretic peptide precursor A (Nppa, formerlyPnd) markers.

Because this difference is marginally significant, the authors note it may be due to chance.

However, among never smokers there was a marginally significant, negative association between urinary cadmium and total testosterone (p-trend = 0.06) and among current smokers there was a marginally significant, positive association between urinary cadmium and free testosterone concentrations (p-trend = 0.09).

We did not find evidence to suggest differences in pregnancy history or labor and delivery characteristics between cases and the sub-cohort with the exception of a marginally significant decreased risk for AML associated with less than adequate prenatal care (HR = 0.57, 95% CI 0.33–1.0) and an increased AML risk associated with maternal gestational weight gain of 30 or more pounds (HR = 2.59, 95% CI 1.27–5.31) based on few cases.

On the other hand, the modified NPI classification showed a marginally significant increase in the HRs of tumour recurrence in the intermediate-high, and high-risk groups, but failed to significantly increase the HRs of tumour death in these groups.

While the study in Finnish smokers found no association (Glynn et al, 1996), the US physi- cians' study found a marginally significant increased risk in men with a severe depletion in plasma folate levels (Ma et al, 1997).

Subjects with a cholecystectomy at least 20 years prior to the diagnosis of pancreatic cancer experienced a 70% increased risk, which was marginally significant.

There was no evidence, among parous women, that increasing parity was associ- ated with risk of mucinous tumours. Relative to a first birth before age 25, a first birth at a later age was associated with a significant (60%) reduced risk of serous borderline tumours, and a marginally significant (40%) decreased risk of endometrioid/clear cell tumours; increasing age at first birth was significantly associated with a decreased risk of these tumour types (Table 6).

We observed significantly positive association between the consumption of rice and stomach cancer mortality in men, and the association was marginally significant in women.

The marginally significant (one-marker subset) SNPs are rs2476601 ( PTPN2 2), and rs237025 and rs577001 (both at the locus of SUMO4 ).

The initial population is constructed by choosing a predefined n major and minor SNP pairs, where a major SNP is randomly selected from a list of marginally significant SNPs detected by the first type of ANOVA models and a minor SNP is randomly selected from a list of marginally non-significant SNPs.