Barely Significant
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may be significant

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In the literature

6 , 7 Existing evidence reports that increasing age, obesity, and reduced ECOG physical performance status may be significant contributors to incidences of reduced RDI. 7 , 8 Exercise has been identified as a compelling supportive therapy that could help maximize RDI and reduce chemotherapy‐related toxicities. 9 , 10 In addition to improvements in physical and patient‐reported outcomes, exercise has the
Exercise during chemotherapy: Friend or foe?
Cancer Med · 2023 · PMC10225227
A) Inhibiting caspase-dependent apoptosis may cause cells to die by necrosis or Caspase-independent apoptosis [ 77 ], B) The activity of Caspase may be significant in cytoskeletal remodelling as well as other physiological activities [ 78 ] that could be inhibited, C) Caspase inhibitors may cause defective cells to survive, leading to survival but with little functional value.
During the literature search, we also identified from the literature sources that there may be significant regional differences in the application of telerehabilitation, and therefore, there is a need to promote telerehabilitation globally, especially outside of East Asia and Europe.
Additional analysis of oscillatory solute dispersion within PVS indicates that advection rather than dispersion is likely the primary transport mechanism for dissolved compounds greater than 66 kDa in the long (> 2 mm) perivascular segments identified here, although dispersion may be significant for smaller compounds in shorter perivascular segments.