“may be significant”

The lymphocyte apoptosis which accompanies neutrophil apoptosis may be significant in pathogenesis of IMD by disrupting the T-B lymphocyte activation and interaction required for generation of bactericidal antibody. 6 7 We have obtained preliminary confirmation of virus-associated lymphocyte apoptosis using flow cytometric assessment of annexin-V binding 30 in IM, which showed enhanced binding by CD4, CD19, and especially CD8, but not natural killer lymphocytes (Smith H, unpublished).

In the light of this theory, the appearance of CD4 + CD8 + double-positive cells in the peripheral blood of some patients after thymectomy may be significant.

There may be significant variability of presentation within families [ 317 ], and 10–20% of renal cases will be accompanied by involvement of other organs, mostly eyes, brain, liver and skeletal system [ 18 ].

As the expected depth for ONSD measurement is anywhere from 2.4 to 2.9 cm, this divergence may be significant.

Additionally, we hypothesize there may be significant cognitive benefits such as increased focus and executive function ( Carelli et al., 2017 ; Angelakis et al., 2007 ), to provide therapeutic effect for those with cognitive impairments, Attention-Deficit/Hyperactivity Disorder ( Lim et al., 2012 ) or Post-Traumatic Stress Disorder ( van der Kolk et al., 2016 ) that the Encephalophone might provide.

It is proposed that these gene blocks may be significant for mammary gland development and maintenance and progression of lactation across human, rat, and mouse.

Since Ras is an upstream target of ERK, the inhibition of Ras/Raf/MEK/ERK pathway by EGCG may be significant to inhibit angiogenesis.

Alterations in this gene can disrupt proper protein folding and membrane localization, impairing its function as a transmembrane receptor, which may be significant in the context of cancer ( 23 , 24 ).

While our cohort did not cite concerns in the ‘private’ domain, there may be significant bother in this domain and it warrants further evaluation with specific questions directed towards this area.

The amino acid sequence composition and molecular characteristics of the peptides may be significant factors contributing to the observed differences in ACE1 inhibition activity ( Yang et al., 2020 ).

This level of uncertainty may be significant, as previous studies have shown that typical minimum clearance ranges from 11 to 15 mm 32 .

The distortion may be significant and have an energy dependence, as spot size and shape vary as a function of gantry angle ( 194 , 195 ), and energy ( 196 ).

This observation suggests that in a larger cohort the trend observed may be significant.

Additionally, increased daily wheelchair use time, higher SCI level, and lower pain domain scores may be significant risk factors for developing overuse syndromes.

This contrasts with our current study in which Oxy CPP causes redistribution of GluN1 and GluA1 in CA3 spines, which may be significant in regards to increasing excitability and synaptic neuroplasticity.

Glial scars and myelin debris in the surrounding environment may be significant inhibitors of axonal regeneration, but their role and switching mechanisms in early neural repair post-ICH remain unclear.

Therefore, increasing long-range correlations in neuronal firing induced by sinusoidal stimulation may be significant for suppressing pathological firing patterns and achieving therapeutic effects.

Therefore, it’s possible that only one type of interaction effect may be significant.

Immunotherapy has offered a second line of treatment; however, only approximately 20% of patients respond, and molecular subtyping of tumors indicates there may be significant overlap in those patients that respond to cisplatin and those patients that respond to immunotherapy.

This tick-killing effect may be significant, as it could interrupt B. burgdorferi transmission during this time.

This article is available from https://www.cureus.com/articles/368443-patterns-of-ear-morbidities-among-pediatric-age-group-a-tertiary-care-hospital-based-study Objective : To determine the prevalence of specific pediatric ear morbidities and assess their association with age and sex, while hypothesizing that there may be significant differences across demographic groups for pediatric ear morbidities.

When the network increases in size, the difference between the average hop count and the sink node in the two structures may be significant.

Although most studies of the effects of CAW have focused on DCS and DON, other health effects may be significant.

The χ 2 test was statistically significant, but it is well known that the test may be significant in large samples even though the magnitudes of model-data discrepancies are slight.

This may be significant for the operational interpretation of results, considering that African Anopheles typically bite at night.