“may be significant”

The reported values thus assume a consistent electrostatic effect of Q A – (c550 bandshift) across all PsbA variants but the shifts induced by Q A – may be significant for the absolute differences of E m (Pheo D1 – /Pheo D1 ).

Although not essential for the action of ACh alone, the role of CaMKII as well as AMPK and CaMKK may be significant under the potentiating action of ANP, and perhaps even more so in response to CCK and BK with their modulatory effects on PFL(3) via Ca 2+ -influx pathways.

In addition, there may be significant differences in the methods of CA for patients with non-paroxysmal AF, which may also affect the risk of recurrence.

The presence of tricuspid regurgitation and/or mitral regurgitation was not considered, and these factors may be significant when studying isovolumetric contraction.

The distinction between resident and circulating innate immune cell populations is becoming increasingly important in understanding key inflammatory mechanisms present in asthma, because recent studies have indicated that there may be significant functional differences in these cell populations ( 16 ).

Furthermore, studies suggest that preadipocytes and ASCs may be significant sources of proinflammatory mediators, such as CCL2 [ 12 ].

Together these data suggest that mitochondrial targeting of viral proteins may be significant through multiple pathways that aid in viral infection.

The role of eukaryotic microorganisms in shaping skin lipid mediators and hence skin physiology may be significant, not only because skin resident fungi have been shown to be able to produce lipid mediators per se but also as certain fungi, such as Malassezia , are known to be causatively linked to inflammatory skin disorders [ 36 ] such as pityriasis versicolor; seborrheic dermatitis; atopic dermatitis; and psoriasis, a chronic immune-mediated disease [ 37 , 38 , 39 ].

However, large amounts of oral health data concerning persons with intellectual disabilities are scarce, although these data may be significant for the evaluation of existing policies [ 12 ].

Systemic chemotherapy is the most often used treatment for breast cancer metastases; however, local treatment may be significant if the case is appropriately selected.

Many patients will continue to purchase DHEA (or equivalents) which are available “over the counter” (OTC) as nutritional supplements, and physicians should caution their patients that there may be significant variation in the actual DHEA content of these OTC preparations [ 75 ].

This may reflect the fact that deprived communities in Glasgow are even poorer than the most deprived fifth of areas across the country; our study communities were in the most deprived 15% of neighbourhoods at the commencement of our study, indicating that there may be significant differences in the experience of poverty between neighbourhoods, even at the lower end of the deprivation spectrum.

This suggests that lateral gene transfers in fungi may be significant enough to make reconstruction of the species phylogeny difficult.

It may be significant that large thymocytes are proliferating ( 38 ), as are WEHI 7.1 thymoma cells, and this status correlated with a modest amount of Mult1 expression and Mult1 induction after heat shock ( Fig. 6 B, C ).

coli , mortality may be significant ( Halvorson, 2009 ).

25 , 26 These may be significant contributors to YKL-40 with SAP.

Our preliminary data suggests that tumour hardness and texture may be significant factors in predicting treatment response, with greater drug dissemination in soft to intermediate textured tumours.

Even a small benefit may be significant due to the safety profile and cost-effectiveness of this class of drugs.

Indeed, our results suggest that (i) MG II may be significant contributors of 2G-GDGTs ( Figure 3 and Table 1 ) and (ii) 2G-GDGT cyclization degree is only weakly impacted by temperature.

In large hospitals, there may be significant discrepancies between different wards and departments.

In sum, the phase of the self-regulatory process (performance-monitoring versus goal-selection), the level of specificity (global self-esteem versus specific qualities), and the amount of autonomy (externally controlled versus self-development) may be significant moderators of the effects of self-enhancing interventions on students’ efforts.

The capacity for biofilm formation at lower temperatures, such as 4°C, may be significant for the bacteria’s ability to persist on seafood surfaces over extended periods [ 18 ].

Secondly, disease modification trials typically have long durations (years) and there may be significant competition for eligible patients carrying a specific genotype.

Last, selection bias may be significant, as we included subjects referred from our sleep center.

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].