“may be significant”

However, in some cases, there may be significant degeneration around the sex-limited allele (Y or W) in the ancestral sex-determining region because recessive deleterious mutations and/or deletions accumulate in the surrounding nonrecombining regions [ 99 – 102 ].

Furthermore, there may be significant variations in drought tolerance among the cultivars [ 42 ].

In Italy as well, varicella direct hospitalization costs may be significant, ranging from EUR 558.44 to EUR 42,608.00 [ 6 ].

Through the analysis of extreme watermelon seed size, we found that there may be significant differences in seed size among different species of watermelon.

However, the collective number of patients seen across most of the United States may be significant, with different institutions having slightly different practices.

The hazard ratios (HRs) of these seven prognostic NSGs are shown in Figure 2B , indicating that AGAP3 , RUVBL1 , and LRFN4 may be significant risk factors for CRC, while TRAP1 and NME1 may be significant protective factors for CRC.

These signals and their receptors may be significant factors in the susceptibility to, or severity of, anaphylaxis in allergic individuals [ 14 ].

Regarding judgements of facial emotional expressions, surprise is an ambiguous emotion (e.g., Kim et al., 2003 ) and, therefore, we expected that there may be significant differences across the binge drinking spectrum in terms of how they are interpreted.

Cost per unit, including platform and auxiliary equipment, such as a ground station, may be significant (500–1,000,000 AUD), but in the appropriate circumstances, subsequent operation may be less expensive than manned aircraft operations or satellite based approaches. 3.2.3.

However, even if a single localized generator contributes minimally to the recorded electrical activity, the resultant effect of many correlated neurons distributed over a large region of space may be significant.

These data on quercetin LM conjugates may be significant for enhancing the biological effects such as the antioxidant properties of quercetin and its conjugated derivatives in the body.

They may be significant in the pathogenesis of neuropathic pain.

Another related issue is that even when a study disaggregates gays/lesbians from bisexuals, men and women may be aggregated into a single group, and gender/sex is typically used as an adjustment variable in these studies [ 33 – 35 ], which can lead to misestimations since there may be significant gender/sex differences within a given sexual orientation (e.g. gay men vs. lesbians).

However, it should be noted that there may be significant overlap in function and in many cases the relative contributions of each cell type (and sub-types) in the responses to cryptococci are not known.

In some cases, there may be significant bone loss around the knee.

This would suggest that the most aggressive forms of MG (Mesenchymal) may be significant targets for virotherapy based on their STAT3 expression [ 19 ].

Geographic location is important as differences in BTM may be significant although moderate.

This suggests that there may be significant differences in biological characteristics, clinical manifestations, treatment response, and prognosis.

However, there may be significant linkage disequilibrium (LD) between adjacent markers in dense SNP marker sets, which can lead to false positive results [ 3 ].

The use of six alternative solvents was investigated (PhMe, CH 2 Cl 2 , CHCl 3 , THF, 1,4-dioxane and DMF), (see the Supporting Information for details) however, only the use of DMF provided any conversion to the product, indicating that solvent polarity may be significant for the success of this transformation.

In contrast, the isolates evaluated herein grew at 30°C lower than expected proposing that there may be significant intraespecific variation.

Limitations The length of time used to study drug interactions, especially for the newer COVID-19 medications, may be too short to observe longer-term interactions that may be significant.

Neuroactive ligand-receptor interaction and purine metabolism were common pathways of total, ‘add’ and ‘miss’ dysregulated genes enrichment analysis; thus, it was inferred that the two pathways may be significant terms in HCC development.

It may be significant, however, that mortality from 43 to 60% was reported in two studies in which smolts were exposed to reproductive steroids and subsequently given a sea water challenge (89,91).

A number of studies have previously estimated the time to perform remote and in-person device checks, yielding a wide range of time estimates, suggesting that there may be significant clinic-to-clinic variability [ 14 , 31 - 33 ].