Barely Significant
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moderately significant

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P<0.11p>0.11

Listed by Hankins, posted since · Hankins (2013) · Otte et al. (2022)

In the literature

33 MIP, MEP, and PFT values (FVC, FEV1) showed a moderately significant relationship, which is consistent with previous research that found a strong correlation between MRPs and FVC and FEV1. 25 , 33 MIP, MEP, and FEV1, FVC in COPD patients showed a highly significant correlation with a positive linear trend. 26 MIP and MEP had a moderate relationship (r= 0.27, p=0.01) with MVV, which is consistent with a study by Pradeep Kumar et al, who found the highest correlation between MVV and MRPs. 26 Because these two factors are linked, respiratory muscle endurance measured by MVV may have a direct impact on respiratory muscle strength measured by MIP and MEP.
The effect of famotidine was more pronounced than melatonin. Conclusion Melatonin, despite its potent antioxidant property, does not significantly affect radiation induced apoptosis in leukocytes derived from normal individuals; however, it has a moderately significant protective effect on in leukocytes derived from BC patients.
Follow-Up of Moderately Significant SNPs To possibly identify SNPs with genuine but weak associations to warfarin dose, we excluded VKORC1 , CYP2C9 , CYP4F2 and identified 40 other GWAS loci for follow-up genotyping exhibiting multivariate regression p-values below 0.0002, and selected 40 SNPs representing these loci for genotyping.
In the most significant HLA-DRA-DQA1 region, conditioning on HLA-DRB1 Leu67 ( P = 1.14 × 10 −29 , OR = 1.3) and HLA-DQA1 His129 ( P = 1.56 × 10 −13 , OR = 1.19) removed the effect of DQA1*01:02 ( P = 7.04 × 10 −22 , OR = 0.75, conditional P value is 0.54), DQA1*03:01 ( P = 3.99 × 10 −10 , OR = 1.27, conditional P value is 0.36), and rs3135359 ( P = 8.82 × 10 −21 , OR = 1.21, conditional P value is 0.06); however, the effect of rs2894257 ( P = 8.16 × 10 −36 , OR = 1.36, conditional P value is 1.2 × 10 −7 ) remained moderately significant.
Eddy (2008) introduced a mechanism for estimating E -values from pHMM Forward scores based on a parameterized exponential distribution, and empirical studies in that paper suggest that HMMER3 E -value estimates are reasonably accurate for search against randomly generated sequences, at least in the range of moderately significant scores.
These data indicate that assessing symptoms in response to all identified E-ACEs helps crystalize the overall developmental burden of adversity experienced by JJI girls, with moderately significant correlations between PTSD symptoms and cumulative/lifespan symptoms supporting a SCITALS adversity measurement approach.