Similarly, mean SU reductions were significantly higher for SEL-212 vs pegloticase (−7.32 and −4.89 mg/dl, respectively; P = 0.0185) in participants with tophi during months 3 and 6 combined, but narrowly missed achieving significance in those without tophi ( Supplementary Table S6 , available at Rheumatology online).
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“narrowly missed achieving significance”
Sighted at
p=0.055
In the literature
Moreover, all statistically significant associations remained unchanged, apart from the risk of new-onset HF (HR, 0.757; 95% Cl, 0.570–1.005), which narrowly missed achieving significance.