In contrast to the increased co-expression of TIGIT and CD39 in all γδ T cells in AML and MM, the clustering of CD39 on Vδ1 in comparison to the corresponding Vδ2 γδ T cell subset was only nearly significant in MM, and not significant in AML.
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“nearly significant”
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p=0.0579p=0.06
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On the other hand, end-of-treatment FDG-PET seems to have some predictive value based on the available studies, with five studies reporting a significant and one study reporting a nearly significant association with PFS and three studies reporting a significant relationship between end-of-treatment FDG-PET status and OS.
By incorporating the diagnoses of TOF and those with either VSD, AVSD, or DORV as separate groups into a model with variables that were identified by univariate analysis as significant or nearly significant, TOF was found to be the only independent risk factor for CS‐AKI in our cohort, and preoperative diuretic use was not found to either increase or decrease the risk for CS‐AKI.
At the highest dose of 350 mg twice daily, treatment with 20E demonstrated a nearly significant improvement in gait speed, supported by evidence of a dose–response effect.
Although ECMO support after HTx is relatively high in our service, it could be explained by the following reasons: a significant increase in the age of the recipients and the percentage of recipients aged more than 60 years; the higher number of patients bridged with VADs, which in our experience more often require postoperative ECMO; despite the nonsignificant increase in the median age of the donors, the percentage of donors aged more than 60 years increased significantly; a nearly significant increase in the ischemic time; and finally an improvement in the global management of ECMO, resulting in a more liberal use of this technique.
P -values below 0.05 were regarded as significant, and those ranging from 0.05 to 0.1 were regarded as nearly significant.
Further analysis stratified by smoking status showed significant (or nearly significant) inverse associations between the “fruit-vegetable-cereal” and the “salad-sauce-pasta/grain” patterns with MBD among current smokers only (β −0.30, p -value 0.02; and β −0.27, p -value 0.06, respectively) ( Supplementary Table S1 ).
The subgroup analysis, performed in survivors and non-survivors, showed a nearly significant older age of non-survivors’ group, with a significant higher incidence in the sub-group of patients aged more than 75 y (71% non-survivors).
The nearly significant difference between the age of the FXS and control group may be a limitation of the study.
Another option might be to increase the production of endogenous TIMP1 by boosting serum MMP7 levels, as we revealed a nearly significant cross-correlation between MMP7 and TIMP1.
Nearly significant increases of mIns were found in the hippocampal of the 10-month-old 5xFAD mice, which reached a statistical significance at 14 months of age, compared to WT.
mRSS at week 48 decreased by 6.1 points in the faSScinate trial, vs a nearly significant change compared with the placebo group (4.4).
Patients with high CSS scores were found to have low DMFT category and better oral care status and these associations were nearly significant.
Patients who participated in PR before (Previous PR) seemed to find PA more enjoyable than those who never enrolled in PR, although the results were only nearly significant.
However, mice on NAF did have statistically elevated levels of liver TNF-α and nearly significant levels of IL-6, but no difference in IL-12p40 or IL-10 ( Figure 1(h) ).
However, an interesting, persistent, positive and nearly significant correlation was observed between the Niño 3 area index and DF during the summer months, and this relationship deserves further investigation.
There was a significant association between life satisfaction and ability to work or study, and the association to living with a partner was nearly significant.
No other intraoperative findings, other than the acetabular rim fractures themselves, demonstrated significant or nearly significant differences between groups ( Table II ).
At the same time, immunofluorescence staining also revealed a statistically significant increase in periostin expression of basal keratinocytes in the lesional and previously-lesional healed epidermis, and it was nearly significant in the non-lesional skin in contrast to healthy skin (Fig. 2 b,c) based on relative fluorescence intensity (RFI).
Low baseline BP and the minimal decrease in BP which was observed between the two phases of treatment could contribute to a nearly significant change in the mean DBP and DOPP, which would not result in higher ABP.
EC was significantly associated with CVD mortality at lag 1 day in the warm season and was nearly significant in the cold season also at lag day 1.
Additionally, male sex (OR = 4.45) was nearly significant, suggesting potential associations that warrant further investigation in a larger survey.
The combination of ezetimibe therapy and ABCG2 variant was significant and nearly significant in this group, respectively.
However, we observed a nearly significant decrease in median daily step count over the latter half of the year (months 7-12).
With regards to cortical measures, in a sample of first-degree relatives of SCZ, SZA, and BD patients with cluster A personality disorders, nearly significant hypogyria was seen in the PCC and in the bilateral caudal ACC compared with HCs [ 126 ].