“nearly significant”

Among the remaining sensitivity analyses, the reduction in LDL-C:HDL-C was significant or nearly significant, except for when strata in which the baseline LDL-C level was optimal were pooled; when strata in which some or all subjects were taking lipid-lowering medications were pooled; and when strata from lower quality studies were pooled.

At 18 months, the A+/T−/N+ group declined (extra decline in MMSE at 18 months = − 3.21 (CI −5.71, − 0.72)), while the A+/T−/N− group approached a nearly significant decline as well (Supplementary Table 7 ).

Despite the sample size, we identified two loci significantly associated with sleep apnea phenotypes in AAs and a third nearly significant association.

There is also a SNP at approximately 71.6 Mbp (which is not in strong LD with the 5 SNPs having significant ADELLE p-values) that is nearly significant using ADELLE, but for which there is also no single expression trait whose p-value is even as small as 9.01e-6.

The baseline BMI was 34 kg/m 2 , both groups were titrated to 0.5 units/kg glargine, and fasting glucose fell similarly from ∼165 to 120 mg/dL; however, there was a nearly significant difference in A1C decrease from 8.0 to 7.3% with placebo and from 7.9 to 6.5% with exenatide, with similar frequency of hypoglycemia and with weight increasing by 4 kg with placebo but no weight change with exenatide.

At week eight, melatonin was associated with significantly less weight gain (mean difference [MD] 3.2 kg, p =0.023), increase in waist circumference (MD 2.83 cm, p =0.041) and TG concentration (MD 62 mg/dl, p =0.090 [nearly significant]) than the placebo.

The mode of exercise also did not yield a significant in-between subgroup significance as the result showed (Hedges' g = −0.89, 95% CI −1.37 to −0.40) for “Swimming,” (Hedges' g = −0.26, 95% CI −0.61 to −0.09) for “Treadmill running” and (Hedges' g = −0.16, 95% CI −0.65 to 0.33, Q-between = 5.44, df = 2, p = 0.07) for “Voluntary wheel running.” Through the fact that this difference was nearly significant, the type of exercise was able to explain 17% of the difference between the subgroups ( R 2 = 0.17).

Nearly significant were differences in knowledge of frequency of screening and not knowing if screening might be painful.

The frequency distribution of the SV alleles showed nearly significant differences (Wilcoxon test, P adj = 0.0678) between the prolific and non-prolific sheep and significant differences (Wilcoxon test, P adj = 0.0429) between the prolific and non-prolific goat populations (Fig. 6 E, F, Additional file 2 : Tables S32 and S33).

Further adjustment for 2-h glucose concentrations resulted in a nearly significant positive trend for all adenomas in asso- ciation with IGF-I.

A nearly significant trend suggested that these patients had a lower rate of recurrence and more prolonged overall, relapse-free, and metastasis-free survival [ 59 ].

In addition, we observed a nearly significant decrease in the Higham score during the WBC period compared to the control period, suggesting a beneficial effect of intense cold exposure on menstrual flow and its management.

The tendency difference for correct/non-correct NOAA series is nearly significant (95%) while uncertainties are all provided for the 2 σ interval.

Nonetheless, in the EXSCEL trial, once-weekly exenatide demonstrated a significant 12% reduction in all-cause mortality and nearly significant decreases in three-point MACE.

ChIP analysis revealed significant and nearly significant hypomethylation of H19 -DMR region II in eutopic and ectopic samples, compared to the control group respectively.

52 , 53 This phenomenon of humoral immunity divergence was also observed in the validation cohorts, where we found genes upregulated by patients with an NKG2A + bias in the chikungunya cohort to display significant overlap with antibody-associated genes and nearly significant overlap for the other COVID-19 cohort ( Figure 2 G).

Overall, the stone-crushers had better pulmonary function than the taxi-drivers, this being significant for FVC and nearly significant for FEV1 and MEF25 ( Table 5 ).

In the present study, the highest Arg level (110% of Lys content) increased the plasma concentrations of caspase-3; a numerical (nearly significant) increase was also noted in the plasma concentrations of caspase-8.

No significant or nearly significant associations with any of the dependent behavioral variables investigated were observed for any of the other personality traits (accuracy: all p 's > .2; RTs: all p 's > .7). 3.1.2.

10 We do note for discussions sake that we observed a nearly significant relationship for % Asain at the block group level, though the relationship did not meet the standard 95% level of confidence.

P < 0.05 was considered statistically significant and 0.05 < P < 0.1 was considered nearly significant.

In linear dose-response analyses, ALA intake was unrelated to T2D risk ( Table 1 ), but a nearly significant nonlinear dose–response association with decreased T2D risk was found for ALA intakes ≤560 mg/d, with an RR of 0.95 (95% CI: 0.90, 1.00).

Patients, in contrast, had only one consultation, with or without images; the only difference between these sets was a nearly significant difference in favour of using images for confidence in the treatment plan.

One limitation of our study is the small sample size particularly affecting some statistical results that are nearly significant.

The nearly significant correlation between circulating intermediate monocyte frequencies and plasma IFABP levels in the relatively small number of macaques in our study validates the interrelation between gut barrier disruption and chronic innate immune activation during prolonged ART.