14 Interestingly, the significantly higher risk of all-cause death at LTF associated with PPI was confined to studies enrolling patients at high preoperative risk of mortality (≥8%, according to the STS-PROM score), while it was of borderline significance in those enrolling patients at medium or low risk.
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“of borderline significance”
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Outcomes Overall, the pooled risk estimate for both ischaemic stroke and composite effectiveness outcomes were of borderline significance (ischaemic stroke: seven studies, 0.86 (95% CI 0.75–0.99), Figure 2 ; composite effectiveness outcomes: nine studies, 0.93 (95% CI 0.85–1.01), Figure 3 ) between DOACs and VKA.
In the case of borderline significance, normal distribution was assessed based on inspection of frequency histograms.
Differences in terms of repeated AldAR and aggregated AldAR levels were of borderline significance.
While demographic and environmental variables were equally distributed, higher (of borderline significance) prevalence of pre-existing ill-health was detected in the intervention group for health status, aids for walking and taking mental health-related medication; this was overcome in the analysis by adjusting for these unequally distributed confounders.
Baseline GFR ( p = 0.065), u-AER ( p = 0.070) and HbA 1c ( p = 0.077) were all of borderline significance.
When the model was adjusted for the benchmark biomarker NT‐proBNP, CERT2 was no longer independently related to CV‐death and it's relation with MACE was of borderline significance, while a strong association for Ln‐transformed NT‐proBNP could be observed: 1.95 (1.69–2.26) and 1.76 (1.55–2.00), respectively for CV death and MACE.
51 However, after adjusting for intakes of Ca and potassium, all these inverse associations not only disappeared but also became positive associations, which were significant for total stroke in women with an HR (95% CI) of 1.81 (1.12 to 2.94) for the highest quintile intake versus the lowest (p for trend, 0.015) and of borderline significance for ischaemic stroke in women (p for trend, 0.081).
More than 5 interrupted RT sessions and large GTV volume (> 50 cm3) were the only statistically significant factors while not receiving all planned concurrent chemotherapy cycles was of borderline significance.
Although there was a difference of borderline significance in dynamics of creatinine concentration changes in time after KTx between Group 1 and 2 ( Figure 8 B), the decrease of creatinine concentration in group 1 was more intense (rANOVA, p = 0.055003).
In these models, older age and the presence of hypertension, urolithiasis, a past history of hydronephrosis and post-operative hydronephrosis were indicated to be independent and significant factors associated with the presence of CKD, whereas the presence of pre-operative hydronephrosis was of borderline significance.
Recent studies suggest that the association of the TGFBR1*6A allele with colon cancer is either weak (OR: 1.2; 95% CI: 1.01–1.43) [ 7 ] or of borderline significance (OR: 1.13; 95% CI: 0.98–1.30) [ 10 ].
In contrast, female survivors of non-CNS tumours had a smaller chance, of borderline significance, of completing upper secondary school than males (RR: 0.83, 95% CI: 0.68–1.01) and were more likely to complete short- and medium-cycle higher education than long-cycle higher education.
However, low levels of happiness the previous day remained of borderline significance after adjusting for neighbourhood perceptions of crime, neighbourhood perceptions of quality, and for both crime and quality.
Thus, VIPI is hardly suitable as a broad preventive measure, especially because we found a tendency, even if just of borderline significance, for parents with good interactional competence and few depressive symptoms to have better outcomes with TAU.
Thus, the levels of IgG3 with specificity for MSP2 3D7, and of IgG1 with specificity for GLURP were both shown to be significantly higher in the AC versus UMA groups, while a similar trend, but of borderline significance, was found for IgG3 directed to the FC27 allele of MSP2.
Associations with EBF at six months Among the probable confounders considered, only birth attendant, and early initiation of breastfeeding were found to have strong evidence of association with EBF, while household size and prenatal care provider were of borderline significance (Table 4 ).
Anemia within three years prior to HAART (p = 0.07), and CD4+ = 51-200 cells/mm 3 (p = 0.06) were of borderline significance.
In the presence of LPS the IMiDs had different effects on the OCR:ECAR ratio; lenalidomide caused a highly significant increase ( Figure 2 F) whereas pomalidomide caused an increase of borderline significance ( Figure 2 G).
Adults with disabilities were more likely than peers without disabilities to be divorced/separated, although this difference was only of borderline significance (OR 2.0, 95% CI 1.0–4.2).
Multiple logistic regression identified younger age and single ventricle anatomy in Group 1 and anemia in Group 2 as significant predictors of an inaccurate LF-VO2; critical illness was of borderline significance in both groups.
When analyzed as percentage of CD11c + cells expressing PD‐L1, the results were of borderline significance (Figure S4 ).
For respiratory cancers, increased risk was associated with only one threshold of ozone, and this result was of borderline significance.
Furthermore, the improvement of glycemic control in the second study was of borderline significance, warranting caution when interpreting the conclusion based on these two studies.
Among patients qualified for nephron-sparing surgery due to CT examination results infiltration of the calyx and renal pelvis was not detected in the majority of cases ( p = 0.00), opposite to radical procedures, where infiltration of the calyces is much more common ( p = 0.02) as well as renal pelvis infiltration ( p = 0.05) (although in the case of renal pelvis infiltration it was of borderline significance) ( Fig. 6 ).