“showed a trend”

However, PD samples showed a trend toward increased CD8 T cells, eosinophils, and elevated neutrophils (p ​= ​0.030, t ​= ​2.28, 95 ​% CI [0.018, 0.001]).

The results showed a trend for the cat and chicken, but were statistically significant for the cow fibrils exposed to EGCG ( Fig. 5 C–F).

Compared with the intratumoral and 6-mm peritumoral radiomics signatures, the DL signature showed a trend of improved discriminative performance, with a C-index of 0.74 (95% CI: 0.70-0.77) in the training set and 0.66 (95% CI: 0.58–0.73) in the test set.

Although the vtc2-4 vtc3-3 double mutants showed a trend toward further reduced NPQ values, the difference was not statistically significant compared with vtc2-4 single mutants.

Kaplan–Meier survival curves ( Figure 9 ) showed a trend toward improved survival in the High/Medium AHR group; however, the difference did not reach statistical significance (log-rank p = 0.276).

Throughout drug intervention, the CON group rats exhibited sustained and stable weight gain compared to the MOD group, and rats in the other treatment groups also showed a trend of slow weight increase.

Fecal continence also showed a trend toward improvement, although it did not reach statistical significance ( p = 0.184).

Results concerning outcome at discharge showed a trend of persistence of symptoms or signs compatible with g -HAT slightly higher in fexinidazole cohort than in pentamidine/NECT cohort (20.0% vs. 6.2%): this observation did not reach statistical significance ( p = 0.230) and still study population is too small to draw consistent conclusions.

While urinary NfL showed a trend toward additional predictive value for 3-month outcome, this effect was stronger and statistically significant for serum NfL.

Clinical severity, as measured by the NIHSS and mRS, showed a trend toward higher scores in the AIS group compared to the CIS group, although these differences did not reach statistical significance (NIHSS: p = 0.053; mRS: p = 0.060).

The study also showed a trend toward lower tau PET signal and less brain volume loss [ 81 ].

The study also showed a trend towards decreasing reproductive rate with age for those with non‐optimal birth characteristics [ 1 ].

The GFAP slope was associated with a higher risk (HR, 1.51; 95% CI, 1.02-2.23) and showed a trend toward further improvement to 0.81 (95% CI, 0.73-0.88).

In primary human CD34 + cells from patients with AML, lower overall basal levels of TET2 expression were observed compared to heathy donor (HD) control CD34 + cells, and those with the lowest levels showed a trend toward stronger upregulation and differentiation potential in response to ATRA treatment, as seen in the most responsive human AML cell lines ( Figures 5G , 5H , and S7H – S7K ).

Fellow eyes showed a trend toward reduction from 214.07 ± 18.93 μm to 210.07 ± 12.04 μm, though this did not reach statistical significance ( p = 0.097).

Compared to March, there were significantly more observations in April and May, while June showed a trend toward higher observations than March (Table 4 ).

Compared to the 5% Vehicle group, MNO-863 5% CFS (cell-free supernatant) showed a trend towards increasing GLP-1 expression.

In contrast, the ASMR and ASDR of HSI-associated gastric cancer in both sexes, men and women in Mongolia showed a trend of first increasing and then decreasing ( Fig 3A – F ).

In contrast, FSFF showed a trend with gradual degradation acceleration toward the end of testing.

Nissl staining showed a trend towards a higher number of normal neurons in serpinf1 −/− treated with CEF.

The overall variation trend of the 20 lipid species observed during the gastric digestion phase indicated that T‐MFG closely resembled HM, whereas S‐MFG showed a trend comparable to Con. 2.3.3.

Within the limitations of this study, both materials proved clinically viable for full-arch implant rehabilitation; however, monolithic zirconia showed a trend toward superior biological and mechanical outcomes.

However, patients harboring AR mutations showed a trend toward improved OS compared to those with wild‐type AR , although the difference did not reach statistical significance (Figure 5A ; p = 0.0728).

Several agents, including nintedanib and hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHi), also showed a trend toward protective effects (RR: 0.59, [95% CI: 0.32–1.09] and RR: 0.67, [95% CI: 0.34–1.29], respectively). 4 Discussion In this study, we used an integrative approach to identify potential therapeutic agents for migraine by leveraging genetic, perturbagen, and real-world claims databases.

In line with the in-silico predictions, RANKL protein levels showed a trend toward downregulation compared to negative controls (Fig. 7 B; Supplementary Fig.