Fourth, more recent experimental evidence indicates that focal inactivations of dorsal or ventral mEC each produce place field expansion, and neither generated increased firing at locations outside the main place field – in fact, that data showed a trend towards a decrease in the number of firing fields exhibited by each place cell following focal inactivations (Figure S7 in Ormond et al., 2015).
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In the literature
Although no statistical significance was found, higher lycopene intake showed a trend to reduce the incidence of PCa.
In consistent with a previous study including both obese and nonobese subjects, 11 LDL and non-HDL-C only showed a trend of association with VFA without statistical significance in our study.
In terms of metastatic distribution, only the abdomen/pelvis metastasis ( P = 0.001) presented with a significantly higher SUVmax, and the positive LN group ( P = 0.058) showed a trend toward higher SUVmax.
In apparent contrast with the fMRI results, the low ES group tended to discriminate the neutral stimuli less from the affective stimuli; they showed a trend toward significance in rating the neutral stimulus more often as either pleasant or unpleasant.
Reduced FA in projections from the right ventral dentate to the thalamus correlated with more severe communication impairments in ASD, while reduced FA in projections from the right dorsal dentate to the thalamus showed a trend-level correlation with daily living skills (Jeong et al., 2012 ).
For example, Wnt10b ligand was detected in 33/44 (75%) osteosarcoma cases and showed a trend towards association with reduced overall survival [310] .
5 , 6 A double-blind, double-dummy, crossover, randomized study carried out by Cazzola et al 7 to explore the acute effects of adding salmeterol to tiotropium in patients with stable COPD showed that the addition of salmeterol to tiotropium elicited a significantly faster onset of action and showed a trend for a greater maximum bronchodilation than single drugs alone.
Conclusions These findings suggest that the pattern of circulating FGF21 does not differ significantly between T2DM and NC,although T2DM patients showed a trend toward higher fasting FGF21 than healthy subjects.
ATP7B mRNA and protein levels modulation, instead, showed a trend similar in both cell lines (Fig. 5 ).
In the present study, left IPC showed a trend of this relationship for PVA sequences, but the correlation failed to reach significance ( P = 0.065).
For this reason, we have included in our interpretation those tracts that showed a trend towards significant disconnection.
Comparisons of levels of tryptophan metabolites between medicated and drug-naïve patients showed a trend towards lower levels of KA and HAA in non-medicated patients in preliminary analyses.
There were no serious adverse events recorded and the treatment group showed a trend toward improved cardiac function.
Percentage of time spent in target range (70–140 mg/dL) showed a trend toward an increase from baseline to end-of-treatment and a trend toward a decrease post-treatment, but this post-treatment decrease in time in target was significant only for the MDI subgroup.
In the present study, although the p-IκB:IκB ratios between AEBS- and vehicle-treated group were not significant, AEBS showed a trend to attenuated NF-κB signaling.
29 Combining the data for 5 months from Hanlon et al with Price et al gave a non-significant decrease, and pooling both with the other two studies showed a trend towards lower cholesterol but this was not significant (p=0.069, I 2 =69.9%; figure 2 ).
The ΔlpfA1 mutant did not have significant reduction in the in vivo colonization model, but showed a trend of lower bacterial recovery from the feces, ceca, and large intestine.
The APAs on the other hand showed a trend towards full recovery.
To our surprise, proteasomal gene expression was rather increased than decreased: the standard catalytic subunits showed a trend towards increased mRNA and protein expression, which was, however, mostly not significant.
Confirming previous results, numbers of circulating naïve B cells were lower in the aged [ 25 ] while numbers of some of the other subsets only showed a trend towards an age-related decline.
CD44v10 showed a trend for enhanced expression in aggressive Ewing sarcoma cells, although not significantly.
The GNF4877-treated mice showed a trend towards improved glucose control demonstrating functionality of the transplanted islets ( Fig. 2l ).
Finally to add to the controversy of the impact of off-pump in neurocognitive function was a report of a long term follow up [ 41 ] on the subject; Patients undergoing off-pump coronary artery bypass showed better attention, performing better at tracking and mentally manipulating information, demonstrated better cognitive reasoning and also showed a trend toward better verbal learning.
No other comparison showed statistical significant, even though exposed wild-type males showed a trend of an increase over control that did not reach significance ( Fig 7A ).