After discovering that the RIF group showed a trend toward an increased risk of adverse obstetric and neonatal outcomes, we then performed multivariate logistic regression analysis to further investigate the association between RIF and these perinatal outcomes, respectively ( Table 2 ).
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Food intake showed a trend of reduction throughout the study, but it was only statistically significant during Week 8 and 12 in both groups (p < 0.05).
An additional patient showed a trend of lower oxygen saturations during a telemedicine visit, prompting evaluation and hospital admission.
While DLK1 levels were suppressed in naive CD4 + T cells, qRT-PCR, ELISA, and flow assays showed a trend toward Th1 subtypes ( Figures 4C–E ).
Another preclinical imaging study using [ 11 C]DED in APP ArcSwe mice showed a trend of increasing tracer binding in APP ArcSwe mice compared with age-matched wildtype mice, but there was large intragroup variation ( Olsen et al., 2018 ).
(2015) showed a trend towards better speech understanding as well as a significant improvement in sound quality after one month of use with an EPS strategy that also extended the clinical electrode-frequency allocation down to two octaves.
Although the data in Table 4 showed a trend where higher SPO 2 /FiO 2 ratio cut-off values were associated with lower ICU admission, this trend was not statistically significant.
Between the four groups, these virulence factors showed a trend of increasing abundance as the disease progressed.
Specifically, the mean drop in EF score showed a trend towards being reduced in the immediate (5.7) and early (6.6) therapy groups compared to late therapy (8.6) group for all nerve sparing groups, though this did not reach statistical significance ( p = 0.097).
The incidence of intraoperative complications showed a trend towards fewer complications in the prehabilitation group (40% of patients in the control group vs. 14.3% in the prehabilitation group).
Patients who received IC were younger, with more frequent t -AML or neo-AML, higher BM blast cells percentage, and more favorable cytogenetics, and they showed a trend to have more NPM1 mutations.
Idasanutlin treatment showed a trend toward improvement in patient-reported outcomes, with a ≥50% reduction in symptom burden per MPN-SAF TSS experienced by 43% of patients at week 32.
Increased Tregs either showed a trend toward association or were significantly associated with poor response and inferior OS, especially in frontline patients (supplemental Figure 5).
In fact, a previous nonrandomized trial showed a trend to reduce the incidence of VAP in the lateral–horizontal position group compared to the semi-recumbent position group, and no serious adverse events occurred in patients positioned in lateral–horizontal decubitus; nevertheless, this study was not conclusive, which may be due to its small sample size.
Although prior treatment with ACT did not affect clinical outcome in this study, it showed a trend toward decreasing sequelae, which was not seen with mortality.
In a previous meta‐analysis, olanzapine showed a trend in the treatment of AN, but due to the limited sample size, the conclusion was blurred.(Dold et al, 2015 ; Rosager et al., 2021 ) In adolescents, although olanzapine as adjuvant treatment showed a trend to improving BMI, due to the limited number of participants enrolled, there was no significant difference.
Although to a lesser extent, IgA clones showed a trend similar to IgG ( Fig. 4B ).
In comparison to the quantification of culturable cells, the pre-incubation with either Ce/De/Di/Ly or subtilisin A also showed a trend toward enhancing C. albicans killing by the antimicrobials.
In the cultured human tonsil cells, the TNF-α response to CpG showed a trend of dose-dependent manner as measured by ELISA without statistical significance (Fig.
The ALBI scores at the time of treatment, 1, 3, and 5 years were -2.56±0.38, -2.67±0.38, -2.83±0.42, and -2.82±0.51 (p = 0.006), respectively, and liver function showed a trend toward improvement.
In addition, gene set enrichment using the Molecular Signature Database HALLMARK_WNT_BETA_CATENIN_SIGNALING showed a trend similar to the β-catenin signaling gene set cataloged in DAVID (fig.
Anti-SAE DM was associated with elderly patients and a low CK level and showed a trend for DM skin lesions, muscle weakness, dysphagia, and concurrent malignancy, albeit not significantly, which may be at least partly due to the limited number of patients in this study.
The ND group showed a trend for increasing levels between 3 and 12 months, while the GFD group showed increasing levels only between 6 and 12 months. 3.4.
Additionally, high expressions of CD133 and CD44V8-10 tended to be associated with the non-response pattern to cisplatin, while the high expressions of ALDH1A1, EpCAM, CD133, CD44V6, and CD44V8-10 showed a trend to be positively correlated with the non-response pattern to gemcitabine significance which was not reached ( Table 3 ).
First, the confirmatory study showed a trend towards excess death despite multiple trial design features that were biased in favor of the melflufen arm.