Compared with the control group, six DEGs showed a trend of first increasing and then decreasing, including Mn-PEPCK1 , Mn-PEPCK3 , Mn-PEPCK4 , Mn-HK , Mn-TPI , and L-lactate dehydrogenase ( Mn-LDH ) ( Figure 7 B–G).
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isolates to each antibiotic class by sample day and treatment showed a trend towards increasing resistance to macrolides in the tylosin group and the combination tylosin/DFM group ( Figure 4 ).
In this cohort of initially treatment-naïve patients, the number of EMT-CTCs prior to treatment showed a trend towards poorer survival.
At higher concentrations, the measured sodium and chloride concentrations showed a trend towards higher values than the calculated concentration.
The results showed a trend towards an increase in BRCA1 expression moving from patients with a “high/high” pattern (H-score = 10) to those with a “low/low” pattern (H-score = 70).
The per-protocol analysis, i.e., adherence to the proposed discharge of low-risk patients, demonstrated a higher risk reduction for MACE favoring the Copeptin group with an HR of 0.47 that showed a trend for statistical significance suggesting higher benefits with protocol adherence and thus corroborating the usefulness of DMS with either cTn or hs-cTnT for risk stratification and guidance of safe early discharge.
Notably, alcohol-fed Nlrp6 -deficient mice showed a trend towards reduced Muc2 expression compared to alcohol-fed WT mice ( Figure 2 c), consistent with a slightly reduced mucus layer in the colon ( Figure 2 b).
However, study data showed a trend towards chemotherapy alone in progression free survival (11 vs. 5.8 months) and overall survival (20 vs. 13.5 months) [ 105 ].
The CG genotype also showed a trend towards a poor outcome, although the comparison to the CC referent genotype was not statistically significant [ 61 ].
The estimates showed a trend towards an increased rate throughout the entire follow-up period ( Table 4 ).
Interestingly, higher doses showed a trend towards better outcomes in this study [ 21 ].
Classification of patients according to the presence of active US synovitis showed a trend to higher clinical disease activity in patients with US synovitis, especially PhGA and 28SJC ( Table 4 ).
When looking at obesity related traits, the G allele showed a trend to lower waist-hip ratio with and without adjusting for BMI when inherited maternally and increased ratio when inherited paternally in both Botnia and HTB.
The subgroup analysis showed a statistically significant difference regarding the adjacent segment ratio between both age groups ( p < 0.05); the differences in degeneration ratio and instability ratio were not significantly different between the two age groups but showed a trend towards a difference ( p -values 0.071 and 0.114, respectively) ( Table 1 ).
At 20 °C and 80% of relative humidity, the fatty acid content of the rice samples showed a trend of first increasing and then decreasing.
The annual average precipitation was 126.22 × 10 8 m 3 , and the precipitation showed a trend of fluctuating increase with a rate of 0.51 × 10 8 m 3 /y, in which precipitation increased sharply in the 1970s to 1980s. 3.2.
Pre-TKR subjects showed a trend of higher mid-stance EKAM (related to knee OA severity) with no clearly defined double peak ( Fig 3D ).
However, ClPRX06 showed a trend of first increasing and then decreasing in the three periods of the two different materials.
A pilot randomized controlled trial looked at adjunctive psychosocial intervention following hospital discharge; participants randomized to enhanced assessment and monitoring showed a trend for increased treatment adherence over time [ 11 ].
FMD after hypoxic breathing showed a trend to increase, therefore suggesting that the influence of hypoxia-triggered microparticle formation is limited in our setting and, possibly, a greater influence of inspired NO.
At the level of the ankle, histological analysis also confirmed a significant reduction of inflammation for the anti-IL17A therapy ( p = 0.047) compared to the vehicle control, while dual blockade and anti-TNF therapies only showed a trend of reduced inflammation ( Figure 2 d), which did not reach significance.
However, though all mean counts for both groups were within the normal physiological ranges, RCRC patients showed a trend towards low circulating lymphocytes.
Newer retrospective data also suggested a similar pattern for gastric and GEJ cancer[ 23 , 24 ], while results from the prospective trials cited below showed a trend for improved outcomes in patients achieving complete response in preoperative therapy.
This also increased the upstream expression of COX-2, which showed a trend increase with the increase in ALA treatment concentrations.
113 , 114 Additionally, although most reports showed a trend or reported increased mtDNA deletion levels in PD, others did not. 109 , 115 Notably, mtDNA deletion levels have been reported to be significantly lower in the cerebellum than in other brain regions. 112 , 116 One of the most recent studies found that patients with PD tended to exhibit deletion levels greater than 60% in the substantia nigra, while markedly lower levels were found in the frontal cortex, cerebellum and putamen.