“showed a trend”

However, they showed a trend for increased prevalence of postinfectious fatigue, in line with our findings of a highest frequency and HR for this outcome symptom.

Conclusions This trial did not meet the primary efficacy endpoints, yet reparixin showed a trend toward limiting disease progression as an add-on therapy in COVID-19 severe pneumonia and was well tolerated.

HIF-2α showed a trend towards downregulation by CSE but the effect was not as pronounced as for HIF-1α (Fig. 2D ).

The measurement of OH-proline showed a trend toward higher values in mice treated with higher bleomycin doses.

However, for omalizumab, a recent meta-analysis in pediatric patients showed a trend but no statistical significance towards better therapeutic response with higher IgE baseline levels (WMD 50.30, 95% CI: − 5.91 to − 106.51) [ 98 ], therefore making the role for IgE as a biomarker for prediction of treatment response uncertain.

When dividing FLI into quartiles, the top quartile had a 1.684 times risk for the prevalent IHD than the bottom quartile, and the risk for prevalent IHD showed a trend towards a more significant risk across the quartiles ( P for trend = 0.002).

Overall, the rates of respiratory infections showed a trend of decline during the years of the global COVID-19 pandemic (2020–2022), probably associated with reduced transmission with the implementation of containment directives such as lockdowns, various social distancing measures, and extensive utilisation of face masks [ 9 , 10 ].

After 7 days iECs cultured in hyperglycemic conditions showed a trend of less migration but no significant difference. iECs in chronic hyperglycemia and euglycemia showed a modest but not statistically significant increase in metabolic activity and increased DNA content from day 2 to day 4. iECs in acute hyperglycemia conditions showed increased metabolic activity and decreased DNA content from day 2 to day 4.

Expression levels of ten model genes showed a trend of increase with the risk score from low to high (Fig. 4 C).

The factor misallocation between the three major industries in the three provinces in the northeast of China was serious at first, and then showed a trend of improvement year by year, and as of 2019, the factor misallocation in the three northeastern provinces has all dropped to between 10% and 20%.

In the Discussion, two messages regarding incorrect classifications and their associated results have been removed as follows: - Page 18, line 22 to 25: “Class II obesity showed a trend toward higher treatment requirements and medical complications, with an odds ratio of 2.9 (p-value 0.222) and 9.8 (p-value 0.090), respectively.

In addition, monocytes recovered from the 9-day culture showed a trend of reduced HLA-DR expression ( Fig 5D ) compared to monocytes cultured without vIL-6 (PBS).

Nevertheless, there was some significant difference in the summer maize experiment, the plant height showed a trend of increasing first and then decreasing with the growth of PFM volume, and the variation range of the PFM groups was −3.3%–5.5% compared with the control groups ( R 2 = −0.74 and −0.56, p > 0.05).

Localization of metastatic sites in dependence to the location of the primary tumor showed a trend toward increased infradiaphragmatic lymph node metastases and peritoneal metastases for subcardial primary tumors.

Our study also showed a trend toward better DFS in patients with any CTAs positive for MAGE-A4, NY-ESO-1, KK-LC-1 and PRAME.

Compared with the 2-week PBOO group, the urodynamic indexes and 12 h urine volume in the 3-week PBOO group showed a trend of further development to the OAB stage.

An 11-year large population-based descriptive study in Taiwan showed a trend of uterine suspension with uterine preservation during the latter years [ 9 ], and the uterus preservation is always considered when there is no pathological finding of uterus [ 4 , 11 ].

Indeed, after stratifying the analysis of the skin microbiome following treatment based on body site, we observed that the abundance of genera associated with disease or lack thereof and significantly altered after balneotherapy showed a trend towards the non-disease condition on the elbows, as for the decreasing Ornithinimicrobium and Mesorhizobium .

The sensitivity analysis results with a reference age of 75 years showed a trend similar to that of the main subgroup analysis (Supplementary Table S4 online).

The results of this study showed a trend indicating that most studies focused on cardiovascular diseases, ،while endocrine and metabolic diseases were the least researched topics.

Some studies showed a trend toward male predominance, although female predominance has also been reported [ 8 ].

HAQ, disease activity (DAS28), and the presence of rheumatoid factor (RF) showed a trend in association with higher CAC; however, statistical significance was not reached.

[ 11 ] found that the relationship between serum betaine and the risk of pancreatic cancer was not linear but showed a trend of first decreasing and then increasing, which is consistent with our study.

While not significantly different from CTL, the RES cohort notably showed a trend toward a higher rate of both state and trait anxiety (30% and 21%, respectively) and stress (86% vs. 67% in CTL).

Although most studies showed a trend toward hyperopia, the change in spherical equivalent was not statistically significant.