A recent retrospective, non-randomised case series to evaluate the safety and efficacy of patients treated topically with ‘Benozzi’s method’ for presbyopia (ie, pilocarpine and diclofenac preservative-free eye-drops) from January 2011 to June 2018, showed a trend towards near vision spectacle independence. 59 Based on data from 910 participants (aged 40–59 years), baseline uncorrected near visual acuity (UNVA) over the 8-year period (as measured by Jaeger scale) improved from 4.74 (SD 1.53) to 1.36 (SD 0.48), while binocular uncorrected distance visual acuity remained stable (baseline 0.00 (SD 0.01) logMAR, 8 years 0.03 (SD 0.04) logMAR.
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gambiae complex species showed a trend towards exophagy that was not observed in Odiennekourani.
10 Over the 11 years observed in this study, 14 out of the 23 variables analyzed for completeness showed a trend to improve the quality of filling out forms: a result considered quite positive, possibly attributed to the creation of more referral centers for the care of people in situations of sexual violence, the training of professionals and their greater familiarity with the notification form.
Of note, PMN DTR mice conditioned with CC1 -deficient neutrophils showed a trend toward higher (albeit not significant) serum transaminase release because of putative proinflammatory phenotype.
Additionally, from the perspective of the spatial pattern, the ES supply in the QTP showed a trend of gradual increase from northwest to southeast ( Figure 4 ).
Nevertheless, the results indicated that alexithymia still showed a trend toward the “diagnosis” score of the YFAS-F.
Moreover, tiagabine showed a trend of higher seizure susceptibility in flies expressing the WT hGAT-1.
According to pathological stages, KIF11 expression showed a trend variation along with the disease progression in ACC, BLCA, LIHC, LUAD, SKCM, BRCA, KIRC, KIRP, LUSC, and UCEC ( Figure 3(a) ).
The variation in the CH 3 OH concentration of the discharged solution showed a trend in response to that of the exhausted CH 4 concentration, although the response was slightly delayed.
Among Europeans, HIV tDNA also showed a trend with a SNP in OSBP (oxysterol-binding protein, required for the replication of viruses such as hepatitis C and Zika [ 70 ] and has been associated with HIV-1 infection of monocyte-derived macrophages from highly-exposed seronegative individuals [ 71 ], q = 0.14).
Mandible displacement showed a trend of group H > TB > V > MA.
However, etiology of cirrhosis (p = 0.09) and the country where the study was performed (p = 0.07) also showed a trend towards different diagnostic performance between groups.
Median total insulin exposure (AUC 0–300 ) showed a trend to decline by 22% (CBX, n.s. ) and 26% (Control, n.s. ), respectively, from days 0 to 7; when both infusion sets were analyzed together, this decline over 7 days was significant ( P = 0.023).
In our study, the unexercised young mice consuming the FAS diet exhibited increased muscle TNF-α, whereas the exercised mice showed a trend of increased muscle TNF-α.
The present study also showed a trend toward a seasonal increase in SAH during winter and spring but with no significant relationships with mean atmospheric pressure or temperature.
During the early years of the HIV pandemic, the virus adapted its codon usage to that of human cells, but, by the end of the 20th century, the codon usage of HIV-1 showed a trend of diverging away from human codon usage patterns, indicating the degeneration of genetic information [ 19 ].
Pooled analysis showed a trend towards an association between older age and increased delirium risk in hospitalized older adults with COVID-19, however the association was not statistically significant; mean difference 4.45 (95% CI: 0.85–8.05; p = 0.016). 3.3.
LPS showed a trend toward increasing Csf1r mRNA levels in microglia while lumateperone tended to reduce this response (LPS = 0.5022, LPS+Luma = −0.04456; one-way ANOVA F (2,29) = 0.9725, p = 0.39; Fig. 5 C ).
In all drug-treated cortical cultures, the number of crossings proximal to the soma (< 100 μm) showed a trend for reduction as compared to controls, whereas the number of crossings of distal neurites (> 100 μm) showed a strong trend for an increase in branching as compared to controls (Fig. 3L-O ).
Serum FGF23 levels were markedly upregulated after repeated doses with both the TIW and QD regimens compared with baseline levels on day 1, and showed a trend towards dose dependency.
We found that ATG9A, YTHDF3, EHD1, and ABHD5 were significantly downregulated in PD samples when compared to healthy, while AP2B1 showed a trend towards decreased expression (Fig. 7a–f ).
As can be seen, SPPORT ( 17 ) and GETUG-AFU 16 ( 16 ) also showed a trend of prolonged OS, though it was not statistically significant.
[ 43 ] found that the proportion of residents' positive emotion toward mandatory waste separation policy showed a trend of decreasing first and then increasing.
Interestingly, Akt1 showed a trend similar to that of Pik3c2a, while eNOS mRNA was significantly downregulated in the PHT group and increased with RS treatment.
found both dexibuprofen 200 mg and 300 mg showed a trend towards superiority for sum of pain intensity difference and total pain relief. 40 Furthermore, Liao L et al. included 311 URTI children with body temperature higher than 38.5°C.