Barely Significant
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“showed a trend”

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showed a trendP = 0.0601.2× alpha
4 In addition, in the ClarIDHy study, treatment with ivosidenib showed a trend for improved overall survival (OS) compared with placebo (HR = 0.69; 95% CI 0.44–1.10; P = 0.060; median OS 10.8 months versus 9.7 months, respectively), which was considered significant after adjusting for patient crossover from placebo to ivosidenib using the rank-preserving structural failure ti
did not reach statistical significancep = 0.061.2× alphaplainly factual
showed a trendp = 0.061.2× alpha
Assessment of hepatic triglyceride levels confirmed that HFD-fed mice had significantly higher liver triglycerides compared to Chow-fed mice ( Fig 4B ) (p < 0.01) but HCD-fed mice only showed a trend towards higher liver triglyceride content, which did not reach statistical significance (p = 0.06).