“showed a trend”

Expression of the rate-limiting enzyme of fructose metabolism Khkc also showed a trend to be increased in HSD-fed mice ( Figure 4E ).

In their study, SMA type III patients showed a trend of lower IQ scores.

In the TCGA-LUAD training, TCGA-LUAD testing, and TCGA-LUAD sets, the high-risk group showed a trend of higher sensitivity to standard chemotherapy drugs (Cisplatin, Docetaxel, Etoposide, Gemcitabine, Paclitaxel, and Vinorelbine) (Fig. 3 B and Additional file 4: Figure S3 B, S3 C).

ICs and SASP biomarkers comparison between males and females within SC and C groups For both SC and C groups, adjusted GLM models showed a trend to lower ICs levels in males compared to females, but no significant differences were found for the SC group; E-Cadherin (aAMR = 0.44; q-value = 0.005) and Siglec-9 (aAMR = 0.48; q = 0.005) were significant for C group (Additional file 8 ).

4 ); however, E171 and ZnO NPs showed a trend to increased TNF-α expression.

Compared with the specimen with the thickness of 4 mm, the ultimate bearing capacity of the specimen with the t = 5 mm, 6 mm, 7 mm, and 8 mm increased by 1.0%, 1.7%, 2.8%, and 3.5% respectively, while the ductility showed a trend of gradual reduction, and degraded by 1.8%, 3.0%, 4.6%, and 5.8% respectively.

MX1 expression showed a trend of higher levels of expression in Delta-infected animals but differences were not statistically significant ( S3C Fig ).

The turmeric group showed a trend toward decreasing TEWL among participants with higher sebum concentrations, while the supplement group showed a statistically significant decrease in TEWL.

Although the results of the present study were difficult to compare with recent data due to differences in disease and GCS regimens, it showed a trend to be smaller compared to previous studies despite the fact that the HPA axis was evaluated by LDST.

Similar to the findings from the ER analysis from the original NDA, the ER analysis using PR-diarrhea assessed by PRO-CTCAE showed a trend of increasing probability of diarrhea (LWS ≥ 3) frequency with increasing steady state exposure (AUCs) (Fig. 2 B).

In another clinical trial conducted in children with high-risk or first-relapsed B-ALL, even patients with MRD less than 0.01% showed a trend of benefiting from blinatumomab when compared with traditional chemotherapy, indicating that deeper MRD must be eradicated to prevent relapse 9 .

To evaluate whether the continuous baseline variables showed a trend across the subject subgroups ordered by disease severity, linear regression (for normally distributed variables) or the Jonckheere-Terpstra test (for non-parametric comparisons) were conducted.

Compared with the young group, the elderly showed a trend of increase in glycolysis which was consistent with gene expression results, and GC reached significance in glycolysis level ( P < 0.05; Fig. 2 C).

In our study, children with TP53 mutations showed a trend of adverse outcomes after CAR-T cell therapy, but without reaching a significant level; hence, further research is needed.

Accuracy on the final two trials, when the aid was removed, showed a trend toward increased accuracy in the transparency condition, but it was not significant ( p = 0.11).

One year after surgery, there were no cardiac events such as arrhythmia or embolism, and cardiac function and MR showed a trend toward improvement.

dorsalis showed a trend of expansion for 1,044 genes in 238 gene families, including odorant-binding proteins (OBPs), chemosensory proteins (CSPs), olfactory receptors (ORs), gustatory receptors (GRs), cytochrome P450, carboxyl/cholinesterase (CCEs), and glutathione-S-transferase (GST).

A reduction in ctDNA fraction or tumour volume showed a trend for better PSA PFS or OS ( Supplementary Fig. 1 ). 3.3. ctDNA molecular profiles Commonly altered genes and pathways in baseline samples ( n = 31) are summarised in Figure 1 and included AR (65%), TP53 (23%), RB1 (26%), TMPRSS2-ERG (42%), PI3K pathway genes (42%), WNT pathway genes (35%), and DNA repair genes (58%).

LIPUS treatment significantly inhibited the infiltration of leukocytes and neutrophils in the heart and showed a trend to decrease monocytes in the DOX‐LIPUS group (Figure 5a–d ).

24 , 25 The mean ratio of [iCa] : [TCa] showed a trend toward higher values after‐ compared to before calving, and displayed a considerable degree of variation with a maximum interquartile range from 47% to 64%.

Compared with the model group, the CAROL group showed a trend of returning to normal, suggesting potential reversal of alcohol-induced metabolic disorder by CAROL treatment.

Three of the 16 studies reporting HRs from multivariate analyses showed a trend for association between elevated Lp(a) levels and MACE vs low Lp(a) levels; however, the association was not significant ( Fig 2A ) [ 22 , 24 , 30 ].

TB treatment initiation and completion data were available for Kyrgyzstan, Nigeria, and Tanzania and showed a trend comparable to the TB notification trend: declining for Kyrgyzstan, slightly increasing for Nigeria, and fluctuating for Tanzania.

As the number of cases increases, we expect to confirm significant changes in other questionnaire domains that showed a trend toward improvement in this study.

Different from WYA, the content of Lactobacillus in WYC showed a trend of increasing first, reaching a peak (34.7%) on the 20th day, and then showing a trend of decreasing.