Barely Significant
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showed a trend

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a trend toward significanceP = 0.0501.0× alpha
showed a trendP = 0.0501.0× alpha
Baseline SCORE2 had a marginal statistical significance (hazard ratio [HR] 1.17, 95% CI 1.00–1.36, P = 0.048), whereas SCORE showed a trend toward significance for CVD events (HR 1.26, 95% CI 0.99–1.60, P = 0.050).
showed a trendP = .051.0× alpha
Mortality Compared to the control group, FCM administration showed a trend towards reduced risk of all-cause death (RR: 0.86, 95% CI: 0.74–1.00, P = .05, Figure 4A ) (absolute risk difference 16 (95% CI 29 to 0) fewer per 1000 patients; moderate certainty) and CV death (RR: 0.86, 95% CI: 0.72–1.02, P = .09, Figure 4B ) (absolute risk difference 12 (95% CI 24 fewer to 2 more) per 1000 patients; moderate certainty) at 1-year follow-up.
showed a trendP = 0.051.0× alpha
The reduction in HbA1c levels was also more significant in the Tai Chi group (9 studies; MD = −1.28%; 95%CI: −2.06 to −0.51) compared to conventional therapies, and Tai Chi showed a trend towards statistical significance in decreasing HbA1c levels (5 studies; MD = −0.24%; 95%CI: −0.49 to 0.00, P = 0.05) compared to the aerobic exercise group.
showed a trendP = 0.0501.0× alpha
Overall, the results did not reveal statistically significant associations in any of the tested models, with the marginal exception of SNP rs743572 ( CYP17A1 ) under the dominant model, which showed a trend toward association (OR = 1.56; 95% CI: 1.00–2.45; P = 0.050), despite moderate heterogeneity ( I 2 = 55.6%).